Croomine (BioDeep_00000237488)

   


代谢物信息卡片


Spiro(furan-2(5H),9-(9H)pyrrolo(1,2-a)azepin)-5-one, decahydro-4-methyl-3-(tetrahydro-4-methyl-5-oxo-2-furanyl)-, (3S-(3alpha(2R*,4R*),9alpha(S*),9aalpha))-

化学式: C18H27NO4 (321.1939982)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC(C2CCC3N2CCCCC32CC(C)C(=O)O2)OC1=O
InChI: InChI=1S/C18H27NO4/c1-11-9-14(22-16(11)20)13-5-6-15-18(7-3-4-8-19(13)15)10-12(2)17(21)23-18/h11-15H,3-10H2,1-2H3/t11-,12+,13-,14-,15-,18-/m0/s1

描述信息

A natural product found particularly in Stemona tuberosa and Stemona phyllantha.

同义名列表

8 个代谢物同义名

Croomine; Spiro(furan-2(5H),9-(9H)pyrrolo(1,2-a)azepin)-5-one, decahydro-4-methyl-3-(tetrahydro-4-methyl-5-oxo-2-furanyl)-, (3S-(3alpha(2R*,4R*),9alpha(S*),9aalpha))-; (3S,3R,9S,9aS)-3-[(2S,4S)-5-keto-4-methyl-tetrahydrofuran-2-yl]-3-methyl-spiro[1,2,3,5,6,7,8,9a-octahydropyrrolo[1,2-a]azepine-9,5-tetrahydrofuran]-2-one; (3S,3R,9S,9aS)-3-methyl-3-[(2S,4S)-4-methyl-5-oxo-tetrahydrofuran-2-yl]spiro[1,2,3,5,6,7,8,9a-octahydropyrrolo[1,2-a]azepine-9,5-tetrahydrofuran]-2-one; (3S,3R,9S,9aS)-3-methyl-3-[(2S,4S)-4-methyl-5-oxo-2-tetrahydrofuranyl]-2-spiro[1,2,3,5,6,7,8,9a-octahydropyrrolo[1,2-a]azepine-9,5-tetrahydrofuran]one; (3S,3R,9S,9aS)-3-methyl-3-[(2S,4S)-4-methyl-5-oxo-oxolan-2-yl]spiro[1,2,3,5,6,7,8,9a-octahydropyrrolo[1,2-a]azepine-9,5-oxolane]-2-one; (3S,3R,9S,9aS)-3-methyl-3-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]spiro[1,2,3,5,6,7,8,9a-octahydropyrrolo[1,2-a]azepine-9,5-oxolane]-2-one; 71239-66-2



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jing-ni Liao, Shan-ding Qin, Xiao-sheng Qu, Kui Lin, Dao-Ping Huang, Feng-xin Li, Lan-lan Fan. [Comparative study of four alkaloids contents and antitussive activities of Stemona tuberosa from different habitats of Guangxi Province]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2014 Nov; 37(11):1956-60. doi: ". [PMID: 26027114]
  • Hui Sun, Wei Dong, Aihua Zhang, Weiming Wang, Xijun Wang. Ultra-performance liquid-chromatography with tandem mass spectrometry performing pharmacokinetic and biodistribution studies of croomine, neotuberostemonine and tuberostemonine alkaloids absorbed in the rat plasma after oral administration of Stemonae Radix. Fitoterapia. 2012 Dec; 83(8):1699-705. doi: 10.1016/j.fitote.2012.09.027. [PMID: 23041522]
  • Yan-Tong Xu, Pang-Chui Shaw, Ren-Wang Jiang, Po-Ming Hon, Yiu-Man Chan, Paul Pui-Hay But. Antitussive and central respiratory depressant effects of Stemona tuberosa. Journal of ethnopharmacology. 2010 Apr; 128(3):679-84. doi: 10.1016/j.jep.2010.02.018. [PMID: 20219659]
  • Harald Greger, Johann Schinnerl, Srunya Vajrodaya, Lothar Brecker, Otmar Hofer. Pandanus alkaloids in Stemonaceae: finding of a plausible biogenetic origin of Stemona alkaloids. Journal of natural products. 2009 Sep; 72(9):1708-11. doi: 10.1021/np900294c. [PMID: 19725518]
  • Song-Lin Li, Ren-Wang Jiang, Po-Ming Hon, Ling Cheng, Hong-Xi Xu, Harald Greger, Paul Pui-Hay But, Pang-Chui Shaw. Quality evaluation of Radix Stemonae through simultaneous quantification of bioactive alkaloids by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors. Biomedical chromatography : BMC. 2007 Oct; 21(10):1088-94. doi: 10.1002/bmc.862. [PMID: 17583876]
  • Johann Schinnerl, Brigitte Brem, Paul Pui-Hay But, Srunya Vajrodaya, Otmar Hofer, Harald Greger. Pyrrolo- and pyridoazepine alkaloids as chemical markers in Stemona species. Phytochemistry. 2007 May; 68(10):1417-27. doi: 10.1016/j.phytochem.2007.03.002. [PMID: 17449078]
  • Yan-Tong Xu, Po-Ming Hon, Ren-Wang Jiang, Ling Cheng, Sheng-Hong Li, Yiu-Pong Chan, Hong-Xi Xu, Pang-Chui Shaw, Paul Pui-Hay But. Antitussive effects of Stemona tuberosa with different chemical profiles. Journal of ethnopharmacology. 2006 Nov; 108(1):46-53. doi: 10.1016/j.jep.2006.04.022. [PMID: 16750339]