Arzanol (BioDeep_00000235844)

   


代谢物信息卡片


Arzanol

化学式: C22H26O7 (402.1678446)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCc1oc(=O)c(Cc2c(O)c(CC=C(C)C)c(O)c(C(C)=O)c2O)c(O)c1C
InChI:

描述信息

同义名列表

1 个代谢物同义名

Arzanol



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Franca Piras, Valeria Sogos, Federica Pollastro, Giovanni Appendino, Antonella Rosa. Arzanol, a natural phloroglucinol α-pyrone, protects HaCaT keratinocytes against H2 O2 -induced oxidative stress, counteracting cytotoxicity, reactive oxygen species generation, apoptosis, and mitochondrial depolarization. Journal of applied toxicology : JAT. 2023 Dec; ?(?):. doi: 10.1002/jat.4570. [PMID: 38152000]
  • Haroon Khan, Kannan R R Rengasamy, Aini Pervaiz, Seyed Mohammad Nabavi, Atanas G Atanasov, Mohammad A Kamal. Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation. European journal of medicinal chemistry. 2018 Jun; 153(?):2-28. doi: 10.1016/j.ejmech.2017.12.059. [PMID: 29329790]
  • Antonella Rosa, Angela Atzeri, Mariella Nieddu, Giovanni Appendino. New insights into the antioxidant activity and cytotoxicity of arzanol and effect of methylation on its biological properties. Chemistry and physics of lipids. 2017 06; 205(?):55-64. doi: 10.1016/j.chemphyslip.2017.05.001. [PMID: 28476462]
  • Orazio Taglialatela-Scafati, Federica Pollastro, Giuseppina Chianese, Alberto Minassi, Simon Gibbons, Warunya Arunotayanun, Blessing Mabebie, Mauro Ballero, Giovanni Appendino. Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. Journal of natural products. 2013 Mar; 76(3):346-53. doi: 10.1021/np3007149. [PMID: 23265253]
  • Pankaj S Kothavade, Dnyaneshwar M Nagmoti, Vipin D Bulani, Archana R Juvekar. Arzanol, a potent mPGES-1 inhibitor: novel anti-inflammatory agent. TheScientificWorldJournal. 2013; 2013(?):986429. doi: 10.1155/2013/986429. [PMID: 24198734]
  • Julia Bauer, Andreas Koeberle, Friederike Dehm, Federica Pollastro, Giovanni Appendino, Hinnak Northoff, Antonietta Rossi, Lidia Sautebin, Oliver Werz. Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. Biochemical pharmacology. 2011 Jan; 81(2):259-68. doi: 10.1016/j.bcp.2010.09.025. [PMID: 20933508]
  • Antonella Rosa, Federica Pollastro, Angela Atzeri, Giovanni Appendino, M Paola Melis, Monica Deiana, Alessandra Incani, Debora Loru, M Assunta Dessì. Protective role of arzanol against lipid peroxidation in biological systems. Chemistry and physics of lipids. 2011 Jan; 164(1):24-32. doi: 10.1016/j.chemphyslip.2010.09.009. [PMID: 20932961]
  • Giovanni Appendino, Michela Ottino, Nieves Marquez, Federica Bianchi, Anna Giana, Mauro Ballero, Olov Sterner, Bernd L Fiebich, Eduardo Munoz. Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum. Journal of natural products. 2007 Apr; 70(4):608-12. doi: 10.1021/np060581r. [PMID: 17315926]
  • Antonella Rosa, Monica Deiana, Angela Atzeri, Giulia Corona, Alessandra Incani, M Paola Melis, Giovanni Appendino, M Assunta Dessì. Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum. Chemico-biological interactions. 2007 Jan; 165(2):117-26. doi: 10.1016/j.cbi.2006.11.006. [PMID: 17194458]