(E)-3-(2-Hydroxyphenyl)-2-propenal (BioDeep_00000023498)

 

Secondary id: BioDeep_00000871760

human metabolite Endogenous natural product


代谢物信息卡片


(2E)-3-(2-hydroxyphenyl)prop-2-enal

化学式: C9H8O2 (148.0524268)
中文名称: 3-(2-羟基苯基)-2-丙烯醛, 2-羟基肉桂醛
谱图信息: 最多检出来源 Bos taurus(endogenous) 50%

分子结构信息

SMILES: C1=CC=C(C(=C1)C=CC=O)O
InChI: InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+

描述信息

(E)-3-(2-Hydroxyphenyl)-2-propenal is found in herbs and spices. (E)-3-(2-Hydroxyphenyl)-2-propenal is a constituent of the bark of Cinnamomum cassia (Chinese cinnamon)

同义名列表

4 个代谢物同义名

(2E)-3-(2-hydroxyphenyl)prop-2-enal; (E)-3-(2-Hydroxyphenyl)-2-propenal; o-Hydroxycinnamaldehyde; 2-Hydroxycinnamaldehyde



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Min Ai Lee, Hyen Joo Park, Hwa-Jin Chung, Won Kyung Kim, Sang Kook Lee. Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling. Journal of natural products. 2013 Jul; 76(7):1278-84. doi: 10.1021/np400216m. [PMID: 23855266]
  • Jung-Yeon Kwon, Su-Hyung Hong, Sun-Dong Park, Sang-Gun Ahn, Jung-Hoon Yoon, Byoung-Mog Kwon, Soo-A Kim. 2'-Benzoyloxycinnamaldehyde inhibits nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells via regulation of AP-1 pathway. European journal of pharmacology. 2012 Dec; 696(1-3):179-86. doi: 10.1016/j.ejphar.2012.09.027. [PMID: 23036374]
  • Jian Zhang, Xu Zhang, Juan Liu, Rong Li, Biao Shen. Isolation of a thermophilic bacterium, Geobacillus sp. SH-1, capable of degrading aliphatic hydrocarbons and naphthalene simultaneously, and identification of its naphthalene degrading pathway. Bioresource technology. 2012 Nov; 124(?):83-9. doi: 10.1016/j.biortech.2012.08.044. [PMID: 22985850]
  • Heehong Hwang, Hyejin Jeon, Jiyeon Ock, Su Hyung Hong, Young-Min Han, Byoung-Mog Kwon, Won-Ha Lee, Myung-Shik Lee, Kyoungho Suk. 2'-Hydroxycinnamaldehyde targets low-density lipoprotein receptor-related protein-1 to inhibit lipopolysaccharide-induced microglial activation. Journal of neuroimmunology. 2011 Jan; 230(1-2):52-64. doi: 10.1016/j.jneuroim.2010.08.021. [PMID: 20933287]
  • Zhao-Li Zhou, Zhi-Guo Luo, Bing Yu, Yi Jiang, Yi Chen, Jian-Ming Feng, Mei Dai, Lin-Jiang Tong, Zheng Li, Yuan-Chao Li, Jian Ding, Ze-Hong Miao. Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide. Molecular cancer. 2010 Oct; 9(?):268. doi: 10.1186/1476-4598-9-268. [PMID: 20932347]
  • Sun Young Kim, Yean Kyoung Koo, Ja Yong Koo, Tran Minh Ngoc, Sam Sik Kang, KiHwan Bae, Yeong Sik Kim, Hye Sook Yun-Choi. Platelet anti-aggregation activities of compounds from Cinnamomum cassia. Journal of medicinal food. 2010 Oct; 13(5):1069-74. doi: 10.1089/jmf.2009.1365. [PMID: 20828311]
  • Tran Minh Ngoc, IkSoo Lee, Do Thi Ha, Hongjin Kim, ByungSun Min, KiHwan Bae. Tyrosinase-inhibitory constituents from the twigs of Cinnamomum cassia. Journal of natural products. 2009 Jun; 72(6):1205-8. doi: 10.1021/np900031q. [PMID: 19555125]
  • Kiho Lee, Byoung-Mog Kwon, Kangjeon Kim, Jekyung Ryu, Soo Jin Oh, Kye Sook Lee, Mu-Gil Kwon, Song-Kyu Park, Jong Soon Kang, Chang Woo Lee, Hwan Mook Kim. Plasma pharmacokinetics and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2009 Mar; 39(3):255-65. doi: 10.1080/00498250802650069. [PMID: 19280524]
  • Jung Ok Ban, Ju Hoon Oh, Tae Myoung Kim, Dae Joong Kim, Heon-Sang Jeong, Sang Bae Han, Jin Tae Hong. Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB. Arthritis research & therapy. 2009; 11(5):R145. doi: 10.1186/ar2819. [PMID: 19788760]
  • J Choi, K T Lee, H Ka, W T Jung, H J Jung, H J Park. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Archives of pharmacal research. 2001 Oct; 24(5):418-23. doi: 10.1007/bf02975187. [PMID: 11693543]