Kopsinine (BioDeep_00000231744)

natural product

代谢物信息卡片

Kopsinine

化学式: C21H26N2O2 (338.1994)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 90.91%

分子结构信息

SMILES: COC(=O)C1CC23CCCN4C2C5(C1(CC3)NC6=CC=CC=C65)CC4
InChI: InChI=1S/C21H26N2O2/c1-25-17(24)15-13-19-7-4-11-23-12-10-20(18(19)23)14-5-2-3-6-16(14)22-21(15,20)9-8-19/h2-3,5-6,15,18,22H,4,7-13H2,1H3

描述信息

A natural product found in Kopsia grandifolia.
Annotation level-1

同义名列表

1 个代谢物同义名

Kopsinine

数据库引用编号

21 个数据库交叉引用编号

ChEBI: CHEBI:68094
PubChem: 7069830
ChEMBL: CHEMBL4790316
KNApSAcK: C00024454
CAS: 559-51-3
MoNA: PR310591
MoNA: RIKENPlaSMA000234
MoNA: RIKENPlaSMA000229
MoNA: RIKENPlaSMA000224
MoNA: RIKENPlaSMA000219
MoNA: RIKENPlaSMA000214
MoNA: RIKENPlaSMA000209
MoNA: RIKENPlaSMA000204
MoNA: RIKENPlaSMA000199
MoNA: RIKENPlaSMA000194
MoNA: RIKENPlaSMA000189
MoNA: RIKENPlaSMA000184
MoNA: RIKENPlaSMA000179
PMhub: MS000013954
MetaboLights: MTBLC68094
LOTUS: LTS0050462

分类词条

Aspidosperma type

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

38 个相关的物种来源信息

4056 - Apocynaceae: LTS0050462
2759 - Eukaryota: LTS0050462
141570 - Hunteria: LTS0050462
141571 - Hunteria umbellata: 10.1016/0031-9422(80)83012-3
141571 - Hunteria umbellata: LTS0050462
1220079 - Hunteria zeylanica: 10.1016/S0031-9422(00)95285-3
1220079 - Hunteria zeylanica: LTS0050462
21101 - Kopsia: 10.1021/NP200008G
21101 - Kopsia: LTS0050462
453901 - Kopsia arborea: 10.1002/HLCA.200690053
453901 - Kopsia arborea: 10.1016/J.PHYTOCHEM.2004.03.027
453901 - Kopsia arborea: 10.1021/NP0702234
453901 - Kopsia arborea: 10.1021/NP200008G
453901 - Kopsia arborea: 10.1071/CH9550129
453901 - Kopsia arborea: LTS0050462
453902 - Kopsia flavida: 10.1071/CH9550129
453902 - Kopsia flavida: LTS0050462
28505 - Kopsia fruticosa: 10.1016/J.PHYTOCHEM.2004.03.027
28505 - Kopsia fruticosa: 10.1021/NP200008G
28505 - Kopsia fruticosa: LTS0050462
1750996 - Kopsia griffithii: 10.1016/S0031-9422(97)00513-X
1750996 - Kopsia griffithii: 10.1021/NP200008G
1750996 - Kopsia griffithii: LTS0050462
3036755 - Kopsia hainanensis: LTS0050462
2508339 - Kopsia officinalis: 10.1002/HLCA.200690053
2508339 - Kopsia officinalis: 10.1021/NP200008G
2508339 - Kopsia officinalis: LTS0050462
1037435 - Kopsia pauciflora: 10.1021/NP200008G
1037435 - Kopsia pauciflora: LTS0050462
1751000 - Kopsia singapurensis: 10.1002/HLCA.200890098
1751000 - Kopsia singapurensis: 10.1021/NP0703747
1751000 - Kopsia singapurensis: 10.1021/NP070401T
1751000 - Kopsia singapurensis: 10.1021/NP200008G
1751000 - Kopsia singapurensis: LTS0050462
3398 - Magnoliopsida: LTS0050462
35493 - Streptophyta: LTS0050462
58023 - Tracheophyta: LTS0050462
33090 - Viridiplantae: LTS0050462

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Jian Zhang, Zhi-Wen Liu, Yong Li, Cui-Jie Wei, Jing Xie, Meng-Fei Yuan, Dong-Mei Zhang, Wen-Cai Ye, Xiao-Qi Zhang. Structurally Diverse Indole Alkaloids with Vasorelaxant Activity from Melodinus hemsleyanus. Journal of natural products. 2020 08; 83(8):2313-2319. doi: 10.1021/acs.jnatprod.9b00925. [PMID: 32683864]
Min-Jia Tan, Chun Yin, Chun-Ping Tang, Chang-Qiang Ke, Ge Lin, Yang Ye. Antitussive indole alkaloids from Kopsia hainanensis. Planta medica. 2011 Jun; 77(9):939-44. doi: 10.1055/s-0030-1250631. [PMID: 21165819]
W Y Huang, G T Liu. [Mechanism of the protective action of kopsinine against hepatotoxicity of carbon tetrachloride]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. 1989 Sep; 10(5):461-4. doi: ". [PMID: 2618736]
W Y Huang, G T Liu. [Protective action of kopsinine against experimental liver injuries in mice]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. 1989 Jan; 10(1):65-8. doi: NULL. [PMID: 2816405]