Dehydrocurvularin (BioDeep_00000231098)

   

natural product


代谢物信息卡片


11,13-dihydroxy-4-methyl-2,4,5,6,7,10-hexahydro-1H-3-benzoxacyclododecine-2,10-dione

化学式: C16H18O5 (290.1154178)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(natural_products) 67.5%

分子结构信息

SMILES: c12c(CC(=O)O[C@H](CCC/C=C/C1=O)C)cc(cc2O)O
InChI: InChI=1S/C16H18O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h4,6-7,9-10,17,19H,2-3,5,8H2,1H3

描述信息

D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins

同义名列表

6 个代谢物同义名

11,13-dihydroxy-4-methyl-2,4,5,6,7,10-hexahydro-1H-3-benzoxacyclododecine-2,10-dione; alpha,beta-Dehydrocurvularin; cis-Dehydrocurvularin; Dehydrocurvularin; trans-Dehydrocurvularin; Dehydro-curvularin



相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sucheta Singh, Surjeet Verma, Dharmendra K Yadav, Anant Kumar, Rekha Tyagi, Priyanka Gupta, Dnyaneshwar U Bawankule, Mahendra P Darokar, Santosh K Srivastava, Alok Kalra. The Bioactive Potential of Culturable Fungal Endophytes Isolated From the Leaf of Catharanthus roseus (L.) G. Don. Current topics in medicinal chemistry. 2021; 21(10):895-907. doi: 10.2174/1568026621666210426123437. [PMID: 33902419]
  • Chao Xiang, Ying Liu, Shi-Ming Liu, Ya-Fei Huang, Ling-An Kong, Huan Peng, Mao-Yan Liu, Jing Liu, De-Liang Peng, Wen-Kun Huang. αβ-Dehydrocurvularin isolated from the fungus Aspergillus welwitschiae effectively inhibited the behaviour and development of the root-knot nematode Meloidogyne graminicola in rice roots. BMC microbiology. 2020 03; 20(1):48. doi: 10.1186/s12866-020-01738-2. [PMID: 32126973]
  • Bharat P Bashyal, E M Kithsiri Wijeratne, Joseph Tillotson, A Elizabeth Arnold, Eli Chapman, A A Leslie Gunatilaka. Chlorinated Dehydrocurvularins and Alterperylenepoxide A from Alternaria sp. AST0039, a Fungal Endophyte of Astragalus lentiginosus. Journal of natural products. 2017 02; 80(2):427-433. doi: 10.1021/acs.jnatprod.6b00960. [PMID: 28139929]
  • E M Kithsiri Wijeratne, G M Kamal B Gunaherath, Vanessa M Chapla, Joseph Tillotson, Fabian de la Cruz, MinJing Kang, Jana M U'Ren, Angela R Araujo, A Elizabeth Arnold, Eli Chapman, A A Leslie Gunatilaka. Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii. Journal of natural products. 2016 Feb; 79(2):340-52. doi: 10.1021/acs.jnatprod.5b00986. [PMID: 26812276]
  • Jianwei Dong, Lixing Zhao, Le Cai, Haixian Fang, Xiuhua Chen, Zhongtao Ding. Antioxidant activities and phenolics of fermented Bletilla formosana with eight plant pathogen fungi. Journal of bioscience and bioengineering. 2014 Oct; 118(4):396-9. doi: 10.1016/j.jbiosc.2014.03.003. [PMID: 24742631]
  • Birgitte Andersen, Morten Hollensted. Metabolite production by different Ulocladium species. International journal of food microbiology. 2008 Aug; 126(1-2):172-9. doi: 10.1016/j.ijfoodmicro.2008.05.036. [PMID: 18599140]
  • Margarita Gutiérrez, Cristina Theoduloz, Jaime Rodríguez, Mauricio Lolas, Guillermo Schmeda-Hirschmann. Bioactive metabolites from the fungus Nectria galligena, the main apple canker agent in Chile. Journal of agricultural and food chemistry. 2005 Oct; 53(20):7701-8. doi: 10.1021/jf051021l. [PMID: 16190620]
  • Jixun Zhan, E M Kithsiri Wijeratne, Christopher J Seliga, Jun Zhang, Elizabeth E Pierson, Leland S Pierson, Hans D Vanetten, A A Leslie Gunatilaka. A new anthraquinone and cytotoxic curvularins of a Penicillium sp. from the rhizosphere of Fallugia paradoxa of the Sonoran desert. The Journal of antibiotics. 2004 May; 57(5):341-4. doi: 10.7164/antibiotics.57.341. [PMID: 15317106]
  • Miyako Kusano, Kazumi Nakagami, Shozo Fujioka, Tsuyoshi Kawano, Atsumi Shimada, Yasuo Kimura. Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp. Bioscience, biotechnology, and biochemistry. 2003 Jun; 67(6):1413-6. doi: 10.1271/bbb.67.1413. [PMID: 12843675]