Hyoscine_butylbromide (BioDeep_00000230974)

 

Secondary id: BioDeep_00000230234, BioDeep_00000395816

PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


3-OXA-9-AZONIATRICYCLO(3.3.1.0 SUP(2,4))NONANE, 9-BUTYL-7-((2S)-3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-9-METHYL-, BROMIDE (1:1),(1.ALPHA.,2.BETA.,4.BETA.,5.ALPHA.,7.BETA.)-

化学式: C21H30NO4+.Br- (439.13580800000005)
中文名称: 丁溴酸东莨菪碱, 丁溴东莨菪碱
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 4.35%

分子结构信息

SMILES: CCCC[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)C.[Br-]
InChI: 1H/q+1

描述信息

Butylscopolamine bromide is an organic bromide salt of butylscopolamine. It is an antispasmodic drug which can relieve painful stomach cramps (including those linked with irritable bowel syndrome), bladder and menstrual cramps. It has a role as a muscarinic antagonist and an antispasmodic drug. It is an organic bromide salt and a quaternary ammonium salt. It contains a butylscopolamine.
Butylscopolamine Bromide is an orally available bromide salt form of butylscopolamine, a quaternary ammonium derivative of the alkaloid scopolamine, with anticholinergic property. Upon oral administration, hyoscine butylbromide binds to and blocks muscarinic receptors located on postganglionic parasympathetic nerve endings and on smooth muscle cells. This blocks the activity of acetylcholine (Ach) and causes its antispasmodic effect in the gastrointestinal (GI), urinary, uterine, and biliary tracts. This agent may also facilitate radiologic visualization of the GI tract.
Antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestinal, urinary, uterine, and biliary tracts, and to facilitate radiologic visualization of the gastrointestinal tract.
C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent

同义名列表

92 个代谢物同义名

3-OXA-9-AZONIATRICYCLO(3.3.1.0 SUP(2,4))NONANE, 9-BUTYL-7-((2S)-3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-9-METHYL-, BROMIDE (1:1),(1.ALPHA.,2.BETA.,4.BETA.,5.ALPHA.,7.BETA.)-; 3-Oxa-9-azoniatricyclo(3.3.1.02,4)nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-; (1R,2R,4S,5S,7R)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0,2,4]nonan-9-ium bromide; (1R,2R,4S,5S,7S)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide; (2R,4S,5S,7s)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0(2,4)]nonane bromide; [(1S,2S,4R,5R)-9-butyl-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate;bromide; 1-alpha-H,5-alpha-H-Tropanium, 8-butyl-6-beta,7-beta-epoxy-3-alpha-hydroxy-, bromide, (-)-tropate; Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide; Hyoscine butylbromide, European Pharmacopoeia (EP) Reference Standard; Hyoscine butylbromide, British Pharmacopoeia (BP) Reference Standard; (-)-Scopolamine N-butyl bromide, >=98\\% (TLC), powder; BUTYLSCOPOLAMINE BROMIDE [GREEN BOOK]; HYOSCINE BUTYLBROMIDE [EP MONOGRAPH]; N-BUTYLSCOPOLAMMONIUM BROMIDE [MI]; (-)-SCOPOLAMINE N-BUTYL BROMIDE; HYOSCINE BUTYLBROMIDE [WHO-DD]; Butylscopolamine bromide [JAN]; (-)-Scopolamine-N-butylbromide; (-)-N-Butylscopolamine bromide; SCOPOLAMINE BUTYLBROMIDE [JAN]; Hyoscin-N-butylbromid [German]; Bromide, N-Butylscopolammonium; N Butylscopolammonium Bromide; N-Butylscopolammonium bromide; HYOSCINE BUTYLBROMIDE [MART.]; N-Butylscopolaminium bromide; Bromide, Butylscopolammonium; Scopolamine N-n-butylbromide; (-)-Scopolamine Butylbromide; Scopolamine N-butyl bromide; Butylscopolammonium Bromide; N-Butylscopolamine bromide; Scopolamine (butylbromide); scopolamine n-butylbromide; Scopolamine butyl bromide; Scopolamine bromobutylate; N-Butylhyoscinium bromide; Hyoscine-N-butyl bromide; Scopolamine butylbromide; N-Butylbromide, Hyoscine; Butylscopolamine bromide; Scopolamine butobromide; Hyoscine N Butylbromide; N-Butylhyoscine bromide; Scopolaminebutylbromide; Hyoscine N-Butylbromide; Hyoscin-N-butyl bromide; Hyoscine butyl bromide; Hyoscine butylbromide; Hyoscin-N-butylbromid; Hyoscine butobromide; hyoscin butobromide; Hyoscinbutylbromide; Butylscopolamine; UNII-0GH9JX37C8; butylscopolamin; Tox21_112031_1; Butylhyoscine; Tox21_112031; Buscolysine; Scopolamine; Buscolamin; 0GH9JX37C8; Buscolysin; Buskolamin; Buscapine; Buscogast; Spasler-P; HybroCare; Buscapina; Scopinal; Scobutyl; Hyocimax; Stilbron; Scopolan; Amisepan; Monospan; Sporamin; Scoburen; Butylmin; Tirantil; Scobutil; Sparicon; Buscopan; Joscine; Donopon; Antipan; Scobron; Stibron; Spasmin; Buscol; Scobro



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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