Praeruptorin (BioDeep_00000230958)

Main id: BioDeep_00000230198

 

PANOMIX_OTCML-2023


代谢物信息卡片


2-Butenoic acid, 2-methyl-, (9R,10R)-9,10-dihydro-8,8-dimethyl-10-(3-methyl-1-oxobutoxy)-2-oxo-2H,8H-benzo[1,2-b:3,4-b]dipyran-9-yl ester, (2Z)-

化学式: C24H28O7 (428.1834938)
中文名称: 白花前胡丙素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C/C=C(C)\C(O[C@@H]1[C@H](OC(CC(C)C)=O)C2=C3C(C=CC(O3)=O)=CC=C2OC1(C)C)=O
InChI: InChI=1S/C24H28O7/c1-7-14(4)23(27)30-22-21(29-18(26)12-13(2)3)19-16(31-24(22,5)6)10-8-15-9-11-17(25)28-20(15)19/h7-11,13,21-22H,12H2,1-6H3/b14-7-/t21-,22-/m1/s1

描述信息

Praeruptorin C is a natural product found in Musineon divaricatum with data available.
Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.7[1].
Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.7[1].

同义名列表

8 个代谢物同义名

2-Butenoic acid, 2-methyl-, (9R,10R)-9,10-dihydro-8,8-dimethyl-10-(3-methyl-1-oxobutoxy)-2-oxo-2H,8H-benzo[1,2-b:3,4-b]dipyran-9-yl ester, (2Z)-; [(9R,10R)-8,8-dimethyl-10-(3-methylbutanoyloxy)-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate; 2-methyl-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3,4-b)dipyran-9-ol ester of 2-butenolc acid; praeruptorine C; Praeruptorin C; Praeruptorin-C; Wulongensin A; Praeruptorin



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Meng Chen, Ruimiao Chang, Liying Xu, Yayun Huang, Hongfen Zhang, Anjia Chen. Simultaneous separation and determination of praeruptorin A, B and C by micellar electrokinetic chromatography using sodium dodecyl sulphate and sodium cholate as mixed micelles. Phytochemical analysis : PCA. 2018 Sep; 29(5):425-431. doi: 10.1002/pca.2746. [PMID: 29392793]
  • Lu Wang, Jing Wang, Le Yang, Shi-Meng Zhou, Shao-Yu Guan, Liu-Kun Yang, Qi-Xin Shi, Ming-Gao Zhao, Qi Yang. Effect of Praeruptorin C on 3-nitropropionic acid induced Huntington's disease-like symptoms in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Feb; 86(?):81-87. doi: 10.1016/j.biopha.2016.11.111. [PMID: 27939523]
  • Wang Wenjie, Lu Houqing, Sun Liming, Zhong Ping, Sun Gengyun. Effects of praeruptorin C on blood pressure and expression of phospholamban in spontaneously hypertensive rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Feb; 21(3):195-8. doi: 10.1016/j.phymed.2013.08.028. [PMID: 24075213]
  • Xu-Nian Zhou, Hui-Chang Bi, Jing Jin, Rong-Rong Deng, Meng-Jia Ying, Yong-Tao Wang, Min Huang. [Induction of UGT1A1 expression by praeruptorin A and praeruptorin C through hCAR pathway]. Yao xue xue bao = Acta pharmaceutica Sinica. 2013 May; 48(5):794-8. doi: ". [PMID: 23888707]
  • Peng-Jiu Yu, Hong Jin, Jun-Yan Zhang, Guang-Fa Wang, Jing-Rong Li, Zheng-Guang Zhu, Yuan-Xin Tian, Shao-Yu Wu, Wei Xu, Jia-Jie Zhang, Shu-Guang Wu. Pyranocoumarins isolated from Peucedanum praeruptorum Dunn suppress lipopolysaccharide-induced inflammatory response in murine macrophages through inhibition of NF-κB and STAT3 activation. Inflammation. 2012 Jun; 35(3):967-77. doi: 10.1007/s10753-011-9400-y. [PMID: 22083490]
  • En-Hui Wei, Man-Ren Rao, Xiu-Ying Chen, Le-Ming Fan, Qi Chen. Inhibitory effects of praeruptorin C on cattle aortic smooth muscle cell proliferation. Acta pharmacologica Sinica. 2002 Feb; 23(2):129-32. doi: NULL. [PMID: 11866872]
  • N C Zhao, W B Jin, X H Zhang, F L Guan, Y B Sun, H Adachi, T Okuyama. Relaxant effects of pyranocoumarin compounds isolated from a Chinese medical plant, Bai-Hua Qian-Hu, on isolated rabbit tracheas and pulmonary arteries. Biological & pharmaceutical bulletin. 1999 Sep; 22(9):984-7. doi: 10.1248/bpb.22.984. [PMID: 10513627]
  • X Wu, C Z Shi, X D Wu. [Effects of praeruptorin-C on cytosolic free calcium in cultured rat heart cells]. Yao xue xue bao = Acta pharmaceutica Sinica. 1993; 28(10):728-31. doi: ". [PMID: 7516604]