Skimmin (BioDeep_00000230900)

 

Secondary id: BioDeep_00000183856

natural product PANOMIX_OTCML-2023


代谢物信息卡片


7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one

化学式: C15H16O8 (324.0845136)
中文名称: 茵芋苷, 茵芋苷
谱图信息: 最多检出来源 Viridiplantae(plant) 8.05%

分子结构信息

SMILES: C1=CC(=CC2=C1C=CC(=O)O2)OC3C(C(C(C(O3)CO)O)O)O
InChI: InChI=1S/C15H16O8/c16-6-10-12(18)13(19)14(20)15(23-10)21-8-3-1-7-2-4-11(17)22-9(7)5-8/h1-5,10,12-16,18-20H,6H2/t10-,12-,13+,14-,15-/m1/s1

描述信息

Skimmin is a member of coumarins and a glycoside.
Skimmin is a natural product found in Artemisia ordosica, Astragalus brachycarpus, and other organisms with data available.
Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].
Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].

同义名列表

20 个代谢物同义名

7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one; 7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-2H-chromen-2-one; 7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one; 7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one; 2H-1-Benzopyran-2-one, 7-(.beta.-D-glucopyranosyloxy)-; 2H-1-Benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-; UMBELLIFERONE 7-O-.BETA.-D-GLUCOPYRANOSIDE; Coumarin, 7-(beta-D-glucopyranosyloxy)-; Glucopyranoside, umbelliferone, beta-D-; Umbelliferone, beta-D-glucopyranoside; COUMARIN 7-O-.BETA.-D-GLUCOSIDE; 7-Hydroxycoumarin-7-glucoside; 7-Hydroxycoumarin glucoside; Skimmin, >=90\\% (LC/MS-UV); UMBELLIFERONE GLUCOSIDE; SKIMMIN, (-)-; SKIMMIN [MI]; Skimmine; Skimmin; SKIMIN



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yan Lou, Hongyu Wu, Jinqi Zheng, Xiaoying He, Zhe Wu, Xiaoyang Lu, Yunqing Qiu. Determination and pharmacokinetic study of skimmin by UHPLC-MS/MS in rat plasma. Journal of pharmaceutical and biomedical analysis. 2020 Feb; 179(?):112969. doi: 10.1016/j.jpba.2019.112969. [PMID: 31767228]
  • Yu-jie Wang, Rong Tan, Li-shi Zhou, Rui Gu, Yi Zhang. [Phenylpropanoids from Saussureae hieracioides]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Jan; 38(1):101-3. doi: . [PMID: 26214878]
  • Rong Tan, Yu-Jie Wang, Yu-Xin Zhang, Li-Shi Zhou, Er Tan, A Ping, Yi Zhang. [Determination of skimmin, scopolin and umbelliferone in Tibetan medicine Saussurea hieracioides by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2014 Mar; 39(6):1054-7. doi: . [PMID: 24956850]
  • Sen Zhang, Jingzhi Yang, Hongyan Li, Yan Li, Yue Liu, Dongming Zhang, Furong Zhang, Wanqi Zhou, Xiaoguang Chen. Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats. European journal of pharmacology. 2012 Oct; 692(1-3):78-83. doi: 10.1016/j.ejphar.2012.05.017. [PMID: 22664227]
  • Wei-Quan Chen, Zhi-Jun Song, Han-Hong Xu. A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii. Bioorganic & medicinal chemistry letters. 2012 Sep; 22(18):5819-22. doi: 10.1016/j.bmcl.2012.07.089. [PMID: 22901896]
  • Jian Xu, Yu-Mei Zhang, Ke-Li Chen, Ning-Hua Tan, Yi-Mei Liu. [A new monoterpenoid glucoside from the twigs of Chamaecyparis obtusa var. breviramea f. crippsii]. Yao xue xue bao = Acta pharmaceutica Sinica. 2012 Sep; 47(9):1179-82. doi: ". [PMID: 23227547]
  • Prince Firdoos Iqbal, Abdul Roouf Bhat, Amir Azam. Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives. European journal of medicinal chemistry. 2009 May; 44(5):2252-9. doi: 10.1016/j.ejmech.2008.06.003. [PMID: 18675491]
  • G Taguchi, T Yazawa, N Hayashida, M Okazaki. Molecular cloning and heterologous expression of novel glucosyltransferases from tobacco cultured cells that have broad substrate specificity and are induced by salicylic acid and auxin. European journal of biochemistry. 2001 Jul; 268(14):4086-94. doi: 10.1046/j.1432-1327.2001.02325.x. [PMID: 11454003]