Calceolarioside (BioDeep_00000230868)
Secondary id: BioDeep_00000230321, BioDeep_00000859413
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C23H26O11 (478.14750460000005)
中文名称: 木通苯乙醇苷B, 木通苯乙醇苷 B
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 95%
分子结构信息
SMILES: C1=CC(=C(C=C1CCOC2C(C(C(C(O2)CO)OC(=O)C=CC3=CC(=C(C=C3)O)O)O)O)O)O
InChI: InChI=1S/C23H26O11/c24-11-18-22(34-19(29)6-3-12-1-4-14(25)16(27)9-12)20(30)21(31)23(33-18)32-8-7-13-2-5-15(26)17(28)10-13/h1-6,9-10,18,20-28,30-31H,7-8,11H2/b6-3+/t18-,20-,21-,22-,23-/m1/s1
描述信息
Calceolarioside A is a hydroxycinnamic acid.
Calceolarioside A is a natural product found in Plantago coronopus, Cassinopsis madagascariensis, and other organisms with data available.
Calceolarioside B is a natural product isolated from Akebia quinata leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM [1].
Calceolarioside B is a natural product isolated from Akebia quinata leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM [1].
同义名列表
10 个代谢物同义名
[(2R,3S,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; [(2R,3S,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; beta-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-; beta-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)-; Calceolarioside A, >=95\\% (LC/MS-ELSD); Calceolarioside B; Calceolarioside A; Calceolarioside; MEGxp0_000507; ACon1_000369
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:177500
- ChEBI: CHEBI:68345
- PubChem: 5273567
- PubChem: 5273566
- ChEMBL: CHEMBL518414
- ChEMBL: CHEMBL481635
- MeSH: calceolarioside A
- ChemIDplus: 0084744285
- chemspider: 57486822
- CAS: 105471-98-5
- CAS: 84744-28-5
- medchemexpress: HY-N0539
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Iva D Stoykova, Ivanka K Koycheva, Biser K Binev, Liliya V Mihaylova, Maria Y Benina, Kalina I Alipieva, Milen I Georgiev. Myconoside and Calceolarioside E Restrain UV-Induced Skin Photoaging by Activating NRF2-Mediated Defense Mechanisms.
International journal of molecular sciences.
2024 Feb; 25(4):. doi:
10.3390/ijms25042441. [PMID: 38397118] - Vanessa Winiewski, Mariana Mesquita Fonseca, Marcos José Salvador, Eduardo Lemos de Sá, Maria Élida Alves Stefanello. Three new naphthoquinones from the tubers of Sinningia mauroana.
Natural product research.
2023 Jan; 37(2):263-268. doi:
10.1080/14786419.2021.1969564. [PMID: 34498959] - Stefano Pieretti, Anella Saviano, Adriano Mollica, Azzurra Stefanucci, Anna Maria Aloisi, Marcello Nicoletti. Calceolarioside A, a Phenylpropanoid Glycoside from Calceolaria spp., Displays Antinociceptive and Anti-Inflammatory Properties.
Molecules (Basel, Switzerland).
2022 Mar; 27(7):. doi:
10.3390/molecules27072183. [PMID: 35408584] - Şevki Adem, Volkan Eyupoglu, Iqra Sarfraz, Azhar Rasul, Ameer Fawad Zahoor, Muhammad Ali, Mohnad Abdalla, Ibrahim M Ibrahim, Abdo A Elfiky. Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 May; 85(?):153310. doi:
10.1016/j.phymed.2020.153310. [PMID: 32948420] - Kristiana M Amirova, Petya A Dimitrova, Andrey S Marchev, Slaveya V Krustanova, Svetlana D Simova, Kalina I Alipieva, Milen I Georgiev. Biotechnologically-Produced Myconoside and Calceolarioside E Induce Nrf2 Expression in Neutrophils.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041759. [PMID: 33578811] - Yujuan Chen, Gang Xue, Feizhou Liu, Xiuling Gong. Immunosuppressive effect of extracts from leaves of Fraxinus Mandshurica Rupr.
Bioengineered.
2017 May; 8(3):212-216. doi:
10.1080/21655979.2016.1221023. [PMID: 27533742] - Rohit K Mishra, Vani Mishra, Anand Pandey, Amit K Tiwari, Himanshu Pandey, Shivesh Sharma, Avinash C Pandey, Anupam Dikshit. Exploration of anti-Malassezia potential of Nyctanthes arbor-tristis L. and their application to combat the infection caused by Mala s1 a novel allergen.
BMC complementary and alternative medicine.
2016 Mar; 16(?):114. doi:
10.1186/s12906-016-1092-2. [PMID: 27036961] - Jian-Hong Yang, Tamara P Kondratyuk, Katherine C Jermihov, Laura E Marler, Xi Qiu, Yongsoo Choi, Hongmei Cao, Rui Yu, Megan Sturdy, Rong Huang, Ying Liu, Li-Qin Wang, Andrew D Mesecar, Richard B van Breemen, John M Pezzuto, Harry H S Fong, Ye-Gao Chen, Hong-Jie Zhang. Bioactive compounds from the fern Lepisorus contortus.
Journal of natural products.
2011 Feb; 74(2):129-36. doi:
10.1021/np100373f. [PMID: 21261296] - Avijit Poddar, Anindita Banerjee, Srijani Ghanta, Sharmila Chattopadhyay. In vivo efficacy of calceolarioside A against experimental visceral leishmaniasis.
Planta medica.
2008 Apr; 74(5):503-8. doi:
10.1055/s-2008-1034373. [PMID: 18543147] - Hui-Min Gao, Zhi-Min Wang, Li Qu, Xue-Tao Fu, Lin Li. [Determination of calceolarioside B in Caulis Akebiae by RP-HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Mar; 32(6):476-8. doi:
". [PMID: 17552147] - Hyoung Ja Kim, Yeon Gyu Yu, Hokoon Park, Yong Sup Lee. HIV gp41 binding phenolic components from Fraxinus sieboldiana var. angustata.
Planta medica.
2002 Nov; 68(11):1034-6. doi:
10.1055/s-2002-35665. [PMID: 12451497] - . .
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