Platycoside E (BioDeep_00000230789)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3-O-beta-glucopyranosyl-(1,6)-beta-glucopyranosyl-(1,6)-beta-D-glucopyranosyl-2beta,3beta,16alpha,23,24-pentahydroxyolean-12-ene-28-oic acid 28-O-beta-apiofuranosyl-(1,3)-beta-xylopyranosyl-(1,4)-alpha-rhamnopyranosyl-(1,2)-alpha-arabinopyranoside

化学式: C69H112O38 (1548.6831252000002)
中文名称: 桔梗皂苷E, 桔梗苷E
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(C(C(O1)OC2C(C(COC2OC(=O)C34CCC(CC3C5=CCC6C(C5(CC4O)C)(CCC7C6(CC(C(C7(CO)CO)OC8C(C(C(C(O8)COC9C(C(C(C(O9)COC1C(C(C(C(O1)CO)O)O)O)O)O)O)O)O)O)O)C)C)(C)C)O)O)O)O)OC1C(C(C(CO1)O)OC1C(C(CO1)(CO)O)O)O
InChI: InChI=1S/C69H112O38/c1-25-50(103-57-49(90)51(30(76)18-94-57)104-61-53(91)68(93,23-73)24-98-61)44(85)48(89)58(99-25)105-52-37(78)29(75)17-95-60(52)107-62(92)69-12-11-63(2,3)13-27(69)26-7-8-34-64(4)14-28(74)54(67(21-71,22-72)35(64)9-10-65(34,5)66(26,6)15-36(69)77)106-59-47(88)43(84)40(81)33(102-59)20-97-56-46(87)42(83)39(80)32(101-56)19-96-55-45(86)41(82)38(79)31(16-70)100-55/h7,25,27-61,70-91,93H,8-24H2,1-6H3/t25-,27-,28-,29-,30+,31+,32+,33+,34+,35+,36+,37-,38+,39+,40+,41-,42-,43-,44-,45+,46+,47+,48+,49+,50-,51-,52+,53-,54-,55+,56+,57-,58-,59-,60-,61-,64+,65+,66+,68+,69+/m0/s1

描述信息

Platycoside E is a triterpenoid saponin. It has a role as a metabolite.
Platycoside E is a natural product found in Platycodon grandiflorus with data available.
A natural product found in Platycodon grandiflorum.

同义名列表

2 个代谢物同义名

3-O-beta-glucopyranosyl-(1,6)-beta-glucopyranosyl-(1,6)-beta-D-glucopyranosyl-2beta,3beta,16alpha,23,24-pentahydroxyolean-12-ene-28-oic acid 28-O-beta-apiofuranosyl-(1,3)-beta-xylopyranosyl-(1,4)-alpha-rhamnopyranosyl-(1,2)-alpha-arabinopyranoside; Platycoside E



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Chi Zhang, Xinhong Wang, Yuanhan Zhong, Li Zhou, Jian Liang, Jinxiang Zeng, Lifen Zhou, En Yuan, Jixiao Zhu, Chong-Zhi Wang, Chun-Su Yuan. Active microbial metabolites study on antitussive and expectorant effects and metabolic mechanisms of platycosides fraction of Platycodonis Radix. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2022 Apr; 1195(?):123171. doi: 10.1016/j.jchromb.2022.123171. [PMID: 35245842]
  • Xinglong Su, Yingying Liu, Lu Han, Zhaojian Wang, Mengyang Cao, Liping Wu, Weimin Jiang, Fei Meng, Xiaohu Guo, Nianjun Yu, Shuangying Gui, Shihai Xing, Daiyin Peng. A candidate gene identified in converting platycoside E to platycodin D from Platycodon grandiflorus by transcriptome and main metabolites analysis. Scientific reports. 2021 05; 11(1):9810. doi: 10.1038/s41598-021-89294-1. [PMID: 33963244]
  • Kyung-Chul Shin, Dae Wook Kim, Hyun Sim Woo, Deok-Kun Oh, Yeong-Su Kim. Conversion of Glycosylated Platycoside E to Deapiose-Xylosylated Platycodin D by Cytolase PCL5. International journal of molecular sciences. 2020 Feb; 21(4):. doi: 10.3390/ijms21041207. [PMID: 32054089]
  • Su-Hwan Kang, Tae-Hun Kim, Kyung-Chul Shin, Yoon-Joo Ko, Deok-Kun Oh. Biotransformation of Food-Derived Saponins, Platycosides, into Deglucosylated Saponins Including Deglucosylated Platycodin D and Their Anti-Inflammatory Activities. Journal of agricultural and food chemistry. 2019 Feb; 67(5):1470-1477. doi: 10.1021/acs.jafc.8b06399. [PMID: 30652865]
  • Hyung Jin Ahn, Hyun Ju You, Myung Su Park, Tony V Johnston, Seockmo Ku, Geun Eog Ji. Biocatalysis of Platycoside E and Platycodin D3 Using Fungal Extracellular β-Glucosidase Responsible for Rapid Platycodin D Production. International journal of molecular sciences. 2018 Sep; 19(9):. doi: 10.3390/ijms19092671. [PMID: 30205574]
  • Eun-Kyung Jeong, In Jin Ha, Yeong Shik Kim, Yun-Cheol Na. Glycosylated platycosides: identification by enzymatic hydrolysis and structural determination by LC-MS/MS. Journal of separation science. 2014 Jan; 37(1-2):61-8. doi: 10.1002/jssc.201300918. [PMID: 24327461]
  • Wei Li, Li-Chun Zhao, Zi Wang, Yi-Nan Zheng, Jian Liang, Hui Wang. Response surface methodology to optimize enzymatic preparation of Deapio-Platycodin D and Platycodin D from Radix Platycodi. International journal of molecular sciences. 2012; 13(4):4089-4100. doi: 10.3390/ijms13044089. [PMID: 22605967]
  • Jung Hoon Choi, Ki-Yeon Yoo, Ok Kyu Park, Choong Hyun Lee, Moo-Ho Won, In Koo Hwang, Shi Yong Ryu, Young Sup Kim, Jae-Seon Yi, Young-Soo Bae, Il-Jun Kang. Platycodin D and 2''-O-acetyl-polygalacin D2 isolated from Platycodon grandiflorum protect ischemia/reperfusion injury in the gerbil hippocampus. Brain research. 2009 Jul; 1279(?):197-208. doi: 10.1016/j.brainres.2009.05.005. [PMID: 19433075]
  • Ling-Jun Li, Zhen-Hua Liu, Yun Chen, Jing-Kui Tian. [Chemical constituents from roots of Platycodon grandiflorum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Sep; 31(18):1506-9. doi: ". [PMID: 17144467]