Platycodin D2 (BioDeep_00000230780)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


platycodigenin 3-O-(glucopyranosyl-(1-3)-glucopyranosyl)-28-O-(apiofuranosyl-(1-3)-xylopyranosyl-(1-4)-rhamnopyranosyl-(1-2)-arabinopyranoside)

化学式: C63H102O33 (1386.6303042)
中文名称: 桔梗皂苷 D2, 桔梗皂苷D2
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(C(C(O1)OC2C(C(COC2OC(=O)C34CCC(CC3C5=CCC6C(C5(CC4O)C)(CCC7C6(CC(C(C7(CO)CO)OC8C(C(C(C(O8)CO)O)OC9C(C(C(C(O9)CO)O)O)O)O)O)C)C)(C)C)O)O)O)O)OC1C(C(C(CO1)O)OC1C(C(CO1)(CO)O)O)O
InChI: InChI=1S/C63H102O33/c1-24-44(91-50-42(80)45(29(71)19-85-50)92-55-48(82)62(84,22-68)23-87-55)39(77)41(79)51(88-24)94-47-35(73)28(70)18-86-54(47)96-56(83)63-12-11-57(2,3)13-26(63)25-7-8-32-58(4)14-27(69)49(61(20-66,21-67)33(58)9-10-59(32,5)60(25,6)15-34(63)72)95-53-43(81)46(37(75)31(17-65)90-53)93-52-40(78)38(76)36(74)30(16-64)89-52/h7,24,26-55,64-82,84H,8-23H2,1-6H3/t24-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35-,36+,37+,38-,39-,40+,41+,42+,43+,44-,45-,46-,47+,48-,49-,50-,51-,52-,53-,54-,55-,58+,59+,60+,62+,63+/m0/s1

描述信息

Platycodin D2 is a triterpenoid saponin. It has a role as a metabolite.
Platycodin D2 is a natural product found in Platycodon grandiflorus with data available.
A natural product found in Platycodon grandiflorum.
Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity[1].
Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity[1].

同义名列表

3 个代谢物同义名

platycodigenin 3-O-(glucopyranosyl-(1-3)-glucopyranosyl)-28-O-(apiofuranosyl-(1-3)-xylopyranosyl-(1-4)-rhamnopyranosyl-(1-2)-arabinopyranoside); Platycodin D2; PlatycodinD2



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mu-Yang Huang, Xiao-Ming Jiang, Yu-Lian Xu, Luo-Wei Yuan, Yu-Chi Chen, Guozhen Cui, Run-Yue Huang, Bo Liu, Yitao Wang, Xiuping Chen, Jin-Jian Lu. Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Sep; 131(?):110537. doi: 10.1016/j.fct.2019.05.045. [PMID: 31150782]
  • Jong-Woo Kim, Sang Jin Park, Jong Hwan Lim, Jae Won Yang, Jung Cheul Shin, Sang Wook Lee, Joo Won Suh, Soon B Hwang. Triterpenoid Saponins Isolated from Platycodon grandiflorum Inhibit Hepatitis C Virus Replication. Evidence-based complementary and alternative medicine : eCAM. 2013; 2013(?):560417. doi: 10.1155/2013/560417. [PMID: 24489585]
  • Yeon Hee Choi, Dae Seok Yoo, Mi-Ran Cha, Chun Whan Choi, Young Sup Kim, Sang-Un Choi, Kang Ro Lee, Shi Yong Ryu. Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells. Journal of natural products. 2010 Nov; 73(11):1863-7. doi: 10.1021/np100496p. [PMID: 20939516]
  • Yong Xie, Shu-Wang He, Hong-Xiang Sun, Duo Li. Platycodin D2 improves specific cellular and humoral responses to hepatitis B surface antigen in mice. Chemistry & biodiversity. 2010 Jan; 7(1):178-85. doi: 10.1002/cbdv.200900002. [PMID: 20087984]
  • Yong Xie, Wen Deng, Hongxiang Sun, Duo Li. Platycodin D2 is a potential less hemolytic saponin adjuvant eliciting Th1 and Th2 immune responses. International immunopharmacology. 2008 Aug; 8(8):1143-50. doi: 10.1016/j.intimp.2008.04.006. [PMID: 18550019]