Ginsenoside C (BioDeep_00000230743)
Main id: BioDeep_00000305092
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C53H90O22 (1078.5923)
中文名称: 人参皂苷 Rb2, 人参皂甙 Rb2, 人参皂苷Rb2
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C[C@H](O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)[C@@H](O)[C@H](O)[C@@H](CO)O2)C(C)(C)[C@]2([H])CC[C@@]3(C)[C@]4(C)CC[C@@]([C@](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)O5)(C)CC/C=C(\C)/C)([H])[C@@]4([H])[C@H](O)C[C@]3([H])[C@@]12C
InChI: InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1
描述信息
Ginsenoside Rb2 is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent. It is a 12beta-hydroxy steroid, a beta-D-glucoside, a disaccharide derivative, a ginsenoside and a tetracyclic triterpenoid. It derives from a hydride of a dammarane.
Ginsenoside Rb2 is a natural product found in Panax vietnamensis, Panax ginseng, and other organisms with data available.
See also: Asian Ginseng (part of); Panax notoginseng root (part of).
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D009676 - Noxae > D000963 - Antimetabolites
D000970 - Antineoplastic Agents
Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects.
Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects.
同义名列表
18 个代谢物同义名
.BETA.-D-GLUCOPYRANOSIDE, (3.BETA.,12.BETA.)-20-((6-O-.ALPHA.-L-ARABINOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-12-HYDROXYDAMMAR-24-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANOSYL-; beta-D-Glucopyranoside, (3-beta,12-beta)-20-((6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-; (3beta,12beta)-20-((6-O-(alpha-L-arabinopyranosyl)-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside; (3beta,12beta)-20-{[6-O-(alpha-L-arabinopyranosyl)-beta-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside; beta-D-GLUCOPYRANOSIDE, (3beta,12beta)-20-((6-O-alpha-L-ARABINOPYRANOSYL-beta-D-GLUCOPYRANOSYL)OXY)-12-HYDROXYDAMMAR-24-EN-3-YL 2-O-beta-D-GLUCOPYRANOSYL-; (3beta,12beta)-20-[(6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside; 20-(alpha-L-arabinopyranosyl-(1->2)-beta-D glucopyranosyloxy)-3beta-(beta-D-glucopyranosyl-(1->2)-beta-D glucopyranosyloxy)dammar-24-en-12beta-ol; 20-((6-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside; 20-[alpha-L-arabinopyranosyl-(1->2)-beta-D glucopyranosyloxy]-3beta-[beta-D-glucopyranosyl-(1->2)-beta-D glucopyranosyloxy]dammar-24-en-12beta-ol; GINSENOSIDE RB2 (CONSTITUENT OF AMERICAN GINSENG, ASIAN GINSENG, AND TIENCHI GINSENG) [DSC]; GINSENOSIDE RB2 (CONSTITUENT OF AMERICAN GINSENG, ASIAN GINSENG, AND TIENCHI GINSENG); Ginsenoside Rb2, analytical standard; (20S)-ginsenoside Rb2; ginsenoside Rb2; Ginsenoside-Rb2; GinsenosideRb2; Ginsenoside C; gingenoside C
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:77152
- PubChem: 6917976
- DrugBank: DB06748
- ChEMBL: CHEMBL449303
- LipidMAPS: LMPR0106080016
- MeSH: ginsenoside Rb2
- ChemIDplus: 0011021139
- CAS: 11021-13-9
- medchemexpress: HY-N0040
- LOTUS: LTS0199787
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
27 个相关的物种来源信息
- 13340 - Aralia: LTS0199787
- 82095 - Aralia elata: 10.1248/CPB.48.838
- 82095 - Aralia elata: LTS0199787
- 4050 - Araliaceae: LTS0199787
- 3650 - Cucurbitaceae: LTS0199787
- 2759 - Eukaryota: LTS0199787
- 182083 - Gynostemma: LTS0199787
- 555433 - Gynostemma yixingense: 10.1016/J.FITOTE.2009.09.009
- 555433 - Gynostemma yixingense: LTS0199787
- 3398 - Magnoliopsida: LTS0199787
- 4053 - Panax: LTS0199787
- 4054 - Panax ginseng: 10.1080/10286020.2010.508035
- 4054 - Panax ginseng: 10.1248/CPB.57.1412
- 4054 - Panax ginseng: 10.5012/BKCS.2010.31.5.1381
- 4054 - Panax ginseng: LTS0199787
- 4054 - Panax ginseng C. A. Mey.: -
- 4054 - Panax ginseng C.A.Mey.: -
- 44586 - Panax notoginseng: 10.1016/S0031-9422(99)00364-7
- 44586 - Panax notoginseng: 10.1021/NP030015L
- 44586 - Panax notoginseng: 10.1248/CPB.31.3205
- 44586 - Panax notoginseng: LTS0199787
- 106132 - Panax vietnamensis: 10.1021/NP000393F
- 106132 - Panax vietnamensis: LTS0199787
- 33090 - Plants: -
- 35493 - Streptophyta: LTS0199787
- 58023 - Tracheophyta: LTS0199787
- 33090 - Viridiplantae: LTS0199787
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yanhuai Ma, Jianliang Li, Jiale Mai, Huizhi Guo, Lingli Ding, Jinglan Li, Jiacong Xiao, Miao Li, Weihua Fang, Shuncong Zhang, Liangliang Xu, Haibin Wang. Ginsenoside Rb2 exhibits therapeutic value for male osteoporosis in orchiectomy mice by suppressing osteoclastogenesis and modulating NF-κB/MAPK signaling pathways.
Food & function.
2024 Feb; 15(3):1583-1597. doi:
10.1039/d3fo04334g
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Biomedical chromatography : BMC.
2021 Nov; 35(11):e5191. doi:
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Food & function.
2021 Jul; 12(13):5793-5805. doi:
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Molecular medicine reports.
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Frontiers of medicine.
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Journal of microbiology and biotechnology.
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Acta pharmacologica Sinica.
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Bioorganic & medicinal chemistry letters.
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Journal of agricultural and food chemistry.
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
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Journal of natural medicines.
2014 Apr; 68(2):395-401. doi:
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Journal of chromatography. A.
2014 Jan; 1325(?):121-8. doi:
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The American journal of Chinese medicine.
2014; 42(1):173-87. doi:
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Journal of biotechnology.
2013 Aug; 167(1):33-40. doi:
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Journal of pharmaceutical and biomedical analysis.
2012 May; 64-65(?):94-7. doi:
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Journal of medicinal food.
2012 Apr; 15(4):350-9. doi:
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Archives of pharmacal research.
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BMB reports.
2009 Apr; 42(4):194-9. doi:
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Journal of pharmaceutical and biomedical analysis.
2004 Apr; 35(1):207-12. doi:
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Acta pharmacologica Sinica.
2003 Feb; 24(2):102-8. doi:
"
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Planta medica.
2002 Jun; 68(6):497-500. doi:
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The American journal of Chinese medicine.
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The Journal of biological chemistry.
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