Bacopasaponin C (BioDeep_00000230684)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-[[(1S,2R,5R,7S,10R,11R,14R,15S,16S,17R,20R)-16-hydroxy-2,6,6,10,16-pentamethyl-17-(2-methylprop-1-enyl)-19,21-dioxahexacyclo[18.2.1.01,14.02,11.05,10.015,20]tricosan-7-yl]oxy]oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

化学式: C46H74O17 (898.4925754000001)
中文名称: (-)-假马齿苋皂苷 C, 假马齿苋皂苷C, (-)-假马齿苋皂苷 C
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CC1COC23CC4(CO2)C(C3C1(C)O)CCC5C4(CCC6C5(CCC(C6(C)C)OC7C(C(C(CO7)O)OC8C(C(C(C(O8)CO)O)O)O)OC9C(C(C(O9)CO)O)O)C)C)C
InChI: InChI=1S/C46H74O17/c1-21(2)14-22-17-57-46-19-45(20-58-46)23(37(46)44(22,7)55)8-9-28-42(5)12-11-29(41(3,4)27(42)10-13-43(28,45)6)61-40-36(63-38-33(53)31(51)26(16-48)60-38)35(24(49)18-56-40)62-39-34(54)32(52)30(50)25(15-47)59-39/h14,22-40,47-55H,8-13,15-20H2,1-7H3/t22-,23-,24+,25-,26+,27+,28-,29+,30-,31+,32+,33-,34-,35+,36-,37+,38+,39+,40+,42+,43-,44+,45+,46-/m1/s1

描述信息

Bascopasaponin C is a natural product found in Bacopa monnieri with data available.
Bacopasaponin C is an indigenous glycoside isolated from Bacopa monniera, with antitumor and anti-leishmanial activities[1][2].

同义名列表

9 个代谢物同义名

(2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-[[(1S,2R,5R,7S,10R,11R,14R,15S,16S,17R,20R)-16-hydroxy-2,6,6,10,16-pentamethyl-17-(2-methylprop-1-enyl)-19,21-dioxahexacyclo[18.2.1.01,14.02,11.05,10.015,20]tricosan-7-yl]oxy]oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; Bascopasaponin C (constituent of bacopa) [DSC]; Bascopasaponin C, (-)-; 3-Glu-Rha-jujobogenin; (-)-Bacopasaponin C; Bascopasaponin C; UNII-26FG38011G; Bacopasaponin C; 26FG38011G



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Chananya Huangteerakul, Hsu Mon Aung, Thitipa Thosapornvichai, Marisa Duangkaew, Amornrat Naranuntarat Jensen, Suchada Sukrong, Kornkanok Ingkaninan, Laran T Jensen. Chemical-Genetic Interactions of Bacopa monnieri Constituents in Cells Deficient for the DNA Repair Endonuclease RAD1 Appear Linked to Vacuolar Disruption. Molecules (Basel, Switzerland). 2021 Feb; 26(5):. doi: 10.3390/molecules26051207. [PMID: 33668176]
  • Rajbir Singh, Ramakrishna Rachumallu, Manisha Bhateria, Jagadeesh Panduri, Rabi Sankar Bhatta. In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity. Xenobiotica; the fate of foreign compounds in biological systems. 2015; 45(8):741-9. doi: 10.3109/00498254.2015.1017752. [PMID: 25869246]
  • Mundkinajeddu Deepak, Agarwal Amit. 'Bacoside B'--the need remains for establishing identity. Fitoterapia. 2013 Jun; 87(?):7-10. doi: 10.1016/j.fitote.2013.03.011. [PMID: 23506783]
  • Sukanya Majumdar, Saraswati Garai, Sumita Jha. Use of the cryptogein gene to stimulate the accumulation of Bacopa saponins in transgenic Bacopa monnieri plants. Plant cell reports. 2012 Oct; 31(10):1899-909. doi: 10.1007/s00299-012-1303-3. [PMID: 22733208]
  • Khalid Rauf, Fazal Subhan, Robert D E Sewell. A Bacoside containing Bacopa monnieri extract reduces both morphine hyperactivity plus the elevated striatal dopamine and serotonin turnover. Phytotherapy research : PTR. 2012 May; 26(5):758-63. doi: 10.1002/ptr.3631. [PMID: 22105846]
  • Ling Peng, Yun Zhou, De Yun Kong, Wei Dong Zhang. Antitumor activities of dammarane triterpene saponins from Bacopa monniera. Phytotherapy research : PTR. 2010 Jun; 24(6):864-8. doi: 10.1002/ptr.3034. [PMID: 19960417]
  • Papolu Bhargava Sriramachandra Murthy, Valivarti Raghava Raju, Tummala Ramakrisana, Mangu Srinivasa Chakravarthy, Katta Vijay Kumar, Sukala Kannababu, Gottumukkala Venkata Subbaraju. Estimation of twelve bacopa saponins in Bacopa monnieri extracts and formulations by high-performance liquid chromatography. Chemical & pharmaceutical bulletin. 2006 Jun; 54(6):907-11. doi: 10.1248/cpb.54.907. [PMID: 16755069]
  • J Sinha, B Raay, N Das, S Medda, S Garai, S B Mahato, M K Basu. Bacopasaponin C: critical evaluation of anti-leishmanial properties in various delivery modes. Drug delivery. 2002 Jan; 9(1):55-62. doi: 10.1080/107175402753413181. [PMID: 11839209]
  • R Pawar, C Gopalakrishnan, K K Bhutani. Dammarane triterpene saponin from Bacopa monniera as the superoxide inhibitor in polymorphonuclear cells. Planta medica. 2001 Nov; 67(8):752-4. doi: 10.1055/s-2001-18351. [PMID: 11731921]