Punicalin (BioDeep_00000230624)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C34H22O22 (782.0602712)
中文名称: 石榴皮鞣素, 安石榴林
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 7.46%
分子结构信息
SMILES: C1C2C(C(C(C(O2)O)O)O)OC(=O)C3=CC(=C(C(=C3C4=C(C(=C5C6=C4C(=O)OC7=C(C(=C(C8=C(C(=C(C=C8C(=O)O1)O)O)O)C(=C67)C(=O)O5)O)O)O)O)O)O)O
InChI: InChI=1S/C34H22O22/c35-6-1-4-9(19(39)17(6)37)11-15-13-14-16(33(50)56-28(13)23(43)21(11)41)12(22(42)24(44)29(14)55-32(15)49)10-5(2-7(36)18(38)20(10)40)31(48)54-27-8(3-52-30(4)47)53-34(51)26(46)25(27)45/h1-2,8,25-27,34-46,51H,3H2/t8-,25-,26-,27-,34?/m1/s1
描述信息
Punicalin is a tannin.
Constituent of pomegranate (Punica granatum) peel. Punicalin is found in fruits and pomegranate.
Punicalin is a hydrolyzable tannin isolated from Punica granatum L. or the leaves of Terminalia catappa L.. Punicalin is a anti-hepatitis B virus (HBV) agent and has anti-inflammatory activity[1][2].
Punicalin is a hydrolyzable tannin isolated from Punica granatum L. or the leaves of Terminalia catappa L.. Punicalin is a anti-hepatitis B virus (HBV) agent and has anti-inflammatory activity[1][2].
同义名列表
8 个代谢物同义名
4,6-(S,S)-gallagyl-D-glucose; punicalin α isomer; punicalin β isomer; CID 92131301; Punicalin; 2,3-dihydroxy-3-{3,4,5,11,17,18,19,22,23,34,35-undecahydroxy-8,14,26,31-tetraoxo-9,13,25,32-tetraoxaheptacyclo[25.8.0.0^{2,7}.0^{15,20}.0^{21,30}.0^{24,29}.0^{28,33}]pentatriaconta-1(27),2(7),3,5,15,17,19,21(30),22,24(29),28(33),34-dodecaen-10-yl}propanal; 3,4,5,11,12,13,21,22,23,26,27,38,39-tridecahydroxy-9,14,17,29,36-pentaoxaoctacyclo[29.8.0.0^{2,7}.0^{10,15}.0^{19,24}.0^{25,34}.0^{28,33}.0^{32,37}]nonatriaconta-1(31),2(7),3,5,19,21,23,25(34),26,28(33),32(37),38-dodecaene-8,18,30,35-tetrone; 4,6-Gallagylglucose
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:167696
- PubChem: 92131301
- PubChem: 5388496
- PubChem: 5464368
- PubChem: 14653353
- Metlin: METLIN93797
- Wikipedia: Punicalin
- MeSH: punicalin
- foodb: FDB018735
- chemspider: 28428695
- CAS: 65995-64-4
- medchemexpress: HY-N0639
- PMhub: MS000210444
- PMhub: MS000066148
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Miodrag Čolić, Dušan Mihajlović, Marina Bekić, Milan Marković, Branka Dragišić, Sergej Tomić, Nataša Miljuš, Katarina Šavikin, Ranko Škrbić. Immunomodulatory Activity of Punicalagin, Punicalin, and Ellagic Acid Differs from the Effect of Pomegranate Peel Extract.
Molecules (Basel, Switzerland).
2022 Nov; 27(22):. doi:
10.3390/molecules27227871. [PMID: 36431972] - Lissethe Palomo-Ligas, Job Estrada-Camacho, Mariana Garza-Ontiveros, José Roberto Vargas-Villanueva, Filiberto Gutiérrez-Gutiérrez, Sendar Daniel Nery-Flores, Jorge Arturo Cañas Montoya, Juan Ascacio-Valdés, Lizeth Guadalupe Campos-Muzquiz, Raul Rodriguez-Herrera. Polyphenolic extract from Punica granatum peel causes cytoskeleton-related damage on Giardia lamblia trophozoites in vitro.
PeerJ.
2022; 10(?):e13350. doi:
10.7717/peerj.13350. [PMID: 35502204] - Marily Gonzalez-Castillo, Maria de Jesus Loera, Juan Ascacio-Valdes, Raul Rodríguez-Herrera, Alejandro Zugasti-Cruz, Mauricio Salinas-Santander, Ana Cecilia Cepeda-Nieto, Ileana Vera-Reyes, Mayela Del Ángel-Martínez, Antonio Morlett-Chavez. Punicalin and ellagic acid from pomegranate peel extract facilitate apoptotic behaviour in the Hela cell line.
Pakistan journal of pharmaceutical sciences.
2021 Nov; 34(6):2181-2189. doi:
". [PMID: 35034879] - Kirsten Berger, Johanna Josefine Ostberg-Potthoff, Tamara Bakuradze, Peter Winterhalter, Elke Richling. Carbohydrate Hydrolase-Inhibitory Activity of Juice-Based Phenolic Extracts in Correlation to Their Anthocyanin/Copigment Profile.
Molecules (Basel, Switzerland).
2020 Nov; 25(22):. doi:
10.3390/molecules25225224. [PMID: 33182561] - Qunqun Guo, Guicai Du, Hongtao Qi, Yanan Zhang, Tongqing Yue, Jingchao Wang, Ronggui Li. A nematicidal tannin from Punica granatum L. rind and its physiological effect on pine wood nematode (Bursaphelenchus xylophilus).
Pesticide biochemistry and physiology.
2017 Jan; 135(?):64-68. doi:
10.1016/j.pestbp.2016.06.003. [PMID: 28043333] - Juan A Ascacio-Valdés, Antonio F Aguilera-Carbó, José J Buenrostro, Arely Prado-Barragán, Raúl Rodríguez-Herrera, Cristóbal N Aguilar. The complete biodegradation pathway of ellagitannins by Aspergillus niger in solid-state fermentation.
Journal of basic microbiology.
2016 Apr; 56(4):329-36. doi:
10.1002/jobm.201500557. [PMID: 26915983] - Yan Wang, Hongchao Zhang, Hao Liang, Qipeng Yuan. Purification, antioxidant activity and protein-precipitating capacity of punicalin from pomegranate husk.
Food chemistry.
2013 May; 138(1):437-43. doi:
10.1016/j.foodchem.2012.10.092. [PMID: 23265509] - Carlos Cruchaga, Elena Anso, María Font, Virginia S Martino, Ana Rouzaut, Juan J Martinez-Irujo. A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer.
The Biochemical journal.
2007 Jul; 405(1):165-71. doi:
10.1042/bj20061831. [PMID: 17355225] - M Jimenez Del Rio, A Ramazanov, S Sikorski, Z Ramazanov, I Chkhikvishvili. A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract.
Georgian medical news.
2006 Nov; ?(140):70-7. doi:
". [PMID: 17179594] - V Martino, J Morales, J J Martínez-Irujo, M Font, A Monge, J Coussio. Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV-1 reverse transcriptase.
Phytotherapy research : PTR.
2004 Aug; 18(8):667-9. doi:
10.1002/ptr.1504. [PMID: 15472920] - I Abe, Y Kashiwagi, H Noguchi, T Tanaka, Y Ikeshiro, Y Kashiwada. Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Journal of natural products.
2001 Aug; 64(8):1010-4. doi:
10.1021/np010100y. [PMID: 11520216] - C C Lin, Y F Hsu, T C Lin, H Y Hsu. Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats.
Phytotherapy research : PTR.
2001 May; 15(3):206-12. doi:
10.1002/ptr.816. [PMID: 11351354] - C C Lin, Y F Hsu, T C Lin. Antioxidant and free radical scavenging effects of the tannins of Terminalia catappa L.
Anticancer research.
2001 Jan; 21(1A):237-43. doi:
". [PMID: 11299741] - C C Lin, Y F Hsu, T C Lin, F L Hsu, H Y Hsu. Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats.
The Journal of pharmacy and pharmacology.
1998 Jul; 50(7):789-94. doi:
10.1111/j.2042-7158.1998.tb07141.x. [PMID: 9720629] - F Buffoni, P Marino, R Pirisino. Partial purification of pig aorta amine oxidases.
The Italian journal of biochemistry.
1976 May; 25(3):191-203. doi:
NULL. [PMID: 8405]