HeterophyllinB (BioDeep_00000230620)
Secondary id: BioDeep_00000230888
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C40H58N8O8 (778.4377388)
中文名称: 太子参环肽B
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 71.7%
分子结构信息
SMILES: CCC(C)C1C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)N2CCCC2C(=O)N3CCCC3C(=O)N4CCCC4C(=O)N1)CC(C)C)CC5=CC=CC=C5
InChI: InChI=1S/C40H58N8O8/c1-5-25(4)34-37(53)44-27(21-26-12-7-6-8-13-26)35(51)42-22-32(49)41-23-33(50)43-28(20-24(2)3)38(54)47-18-10-15-30(47)40(56)48-19-11-16-31(48)39(55)46-17-9-14-29(46)36(52)45-34/h6-8,12-13,24-25,27-31,34H,5,9-11,14-23H2,1-4H3,(H,41,49)(H,42,51)(H,43,50)(H,44,53)(H,45,52)/t25-,27-,28-,29-,30-,31-,34-/m0/s1
描述信息
Heterophyllin B is a natural product found in Pseudostellaria heterophylla with data available.
Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer[1].
Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer[1].
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Wanli Xue, Rui Sun, Zheng Hao, Zhenzhen Xing, Hongjie Cheng, Lei Shao. Heterophyllin B ameliorates gastric cancer tumor growth through activating ER stress.
Tissue & cell.
2023 Aug; 83(?):102129. doi:
10.1016/j.tice.2023.102129
. [PMID: 37406539] - Yunhai Wei, Lei Yin, Jinyu Zhang, Jianing Tang, Xiaofeng Yu, Zhongxin Wu, Yuhai Gao. Heterophyllin B inhibits the malignant phenotypes of gastric cancer cells via CXCR4.
Human cell.
2023 Mar; 36(2):676-688. doi:
10.1007/s13577-022-00824-z
. [PMID: 36539682] - Jiahang Deng, Xinyue Feng, Longjian Zhou, Chuantong He, Huilin Li, Juan Xia, Yuewei Ge, Yuntao Zhao, Cai Song, Lei Chen, Zhiyou Yang. Heterophyllin B, a cyclopeptide from Pseudostellaria heterophylla, improves memory via immunomodulation and neurite regeneration in i.c.v.Aβ-induced mice.
Food research international (Ottawa, Ont.).
2022 08; 158(?):111576. doi:
10.1016/j.foodres.2022.111576
. [PMID: 35840261] - Zhiyou Yang, Cai Zhang, Xiaohong Li, Zhihui Ma, Yuewei Ge, Zhongji Qian, Cai Song. Heterophyllin B, a cyclopeptide from Pseudostellaria heterophylla, enhances cognitive function via neurite outgrowth and synaptic plasticity.
Phytotherapy research : PTR.
2021 Sep; 35(9):5318-5329. doi:
10.1002/ptr.7212
. [PMID: 34328653] - Wai-Ou Zhao, Li Pang, Ning Dong, Shu Yang. LC-ESI-MS/MS analysis and pharmacokinetics of heterophyllin B, a cyclic octapeptide from Pseudostellaria heterophylla in rat plasma.
Biomedical chromatography : BMC.
2015 Nov; 29(11):1693-9. doi:
10.1002/bmc.3481
. [PMID: 25967583]