Rosamultin (BioDeep_00000230534)

   

PANOMIX_OTCML-2023


代谢物信息卡片


[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate

化学式: C36H58O10 (650.4029768)
中文名称: 野蔷薇苷, 罗莎白素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCC2(C(=O)OC3OC(CO)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C2C1(C)O
InChI: InChI=1S/C36H58O10/c1-18-10-13-36(30(43)46-29-26(41)25(40)24(39)21(17-37)45-29)15-14-33(5)19(27(36)35(18,7)44)8-9-23-32(4)16-20(38)28(42)31(2,3)22(32)11-12-34(23,33)6/h8,18,20-29,37-42,44H,9-17H2,1-7H3/t18-,20+,21-,22?,23+,24-,25+,26-,27+,28-,29+,32+,33-,34-,35-,36+/m1/s1

描述信息

Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2].
Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2].

同义名列表

5 个代谢物同义名

[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aS,6aS,6bR,10S,11S,12aR,14bR)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate; Urs-12-en-28-oic acid, 2,3,19-trihydroxy-, beta-D-glucopyranosyl ester, (2alpha,3beta)-; 1-O-(2,3,19-Trihydroxy-28-oxours-12-en-28-yl)hexopyranose; Rosamultin



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Luan He, Ning Liu, Kexin Wang, Ling Zhang, Dan Li, Zhixiang Wang, Guoqiang Xu, Yanli Liu, Qiongming Xu. Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway. Phytotherapy research : PTR. 2021 Nov; 35(11):6343-6358. doi: 10.1002/ptr.7285. [PMID: 34533242]
  • Qiang Liu, Yan Wang. Determination of rosamultin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomedical chromatography : BMC. 2020 Feb; 34(2):e4728. doi: 10.1002/bmc.4728. [PMID: 31657468]
  • Chaofeng Shi, Li Zhan, Yuqiang Wu, Zhengchao Li, Jianyu Li, Yaxiao Li, Jinxia Wei, Yongliang Zhang, Lingzhi Li. Kaji-Ichigoside F1 and Rosamultin Protect Vascular Endothelial Cells against Hypoxia-Induced Apoptosis via the PI3K/AKT or ERK1/2 Signaling Pathway. Oxidative medicine and cellular longevity. 2020; 2020(?):6837982. doi: 10.1155/2020/6837982. [PMID: 32318240]
  • Guang Chen, Zong-Quan Wang, Ji-Ming Jia. Three minor novel triterpenoids from the leaves of Diospyros kaki. Chemical & pharmaceutical bulletin. 2009 May; 57(5):532-5. doi: 10.1248/cpb.57.532. [PMID: 19420791]
  • Jong Cheol Park, Sang Chul Kim, Myeong Rak Choi, Sang Ho Song, Eun Jeong Yoo, Sung Hwan Kim, Hirotsugu Miyashiro, Masao Hattori. Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa. Journal of medicinal food. 2005; 8(1):107-9. doi: 10.1089/jmf.2005.8.107. [PMID: 15857219]
  • Jong Cheol Park, Sang Chul Kim, Jong Moon Hur, Seong Hee Choi, Kab Yeon Lee, Jong Won Choi. Anti-hepatotoxic effects of Rosa rugosa root and its compound, rosamultin, in rats intoxicated with bromobenzene. Journal of medicinal food. 2004; 7(4):436-41. doi: 10.1089/jmf.2004.7.436. [PMID: 15671686]
  • X Lu, W Xu, J Shen, G Han. [Chemical studies on Campylotropis hirtella (Franch. Schindl.)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1997 Nov; 22(11):680-2, 704. doi: . [PMID: 11243186]
  • X Y Wang. [Effects of constituents of the roots of Rosa multiflora on hyperlipemia]. Zhong yao tong bao (Beijing, China : 1981). 1986 Jun; 11(6):55-6. doi: ". [PMID: 2948697]