Gleditsoside B (BioDeep_00000230525)

Main id: BioDeep_00000230963

 

PANOMIX_OTCML-2023


代谢物信息卡片


(4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

化学式: C36H58O9 (634.4080618)
中文名称: 早莲苷 A, 旱莲苷A
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C)[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)CC[C@@](C(O)=O)6[C@H](O)C[C@](C)5[C@@](C)4CC[C@@]13[H]
InChI: InChI=1S/C36H58O9/c1-31(2)14-15-36(30(42)43)20(16-31)19-8-9-23-33(5)12-11-25(45-29-28(41)27(40)26(39)21(18-37)44-29)32(3,4)22(33)10-13-34(23,6)35(19,7)17-24(36)38/h8,20-29,37-41H,9-18H2,1-7H3,(H,42,43)/t20-,21+,22-,23+,24+,25-,26+,27-,28+,29-,33-,34+,35+,36+/m0/s1

描述信息

Echinocystic acid 3-glucoside is a triterpenoid saponin.
Ecliptasaponin A is a natural product found in Eclipta alba and Eclipta prostrata with data available.
Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate[1]. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory[2].
Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate[1]. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory[2].

同义名列表

14 个代谢物同义名

(4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-5-oxidanyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; Olean-12-en-28-oic acid, 3-(b-D-glucopyranosyloxy)-16-hydroxy-,(3b,16a)-; Echinocystic acid 3-O-.beta.-D-glucopyranoside; Eclalbasaponin II, analytical standard; Echinocystic acid-3-o-glucoside; Echinocystic acid 3-glucoside; ECHINOCYSTICACID-3-GLUCOSIDE; Eclalbasaponin II; Ecliptasaponin A; Gleditschoside B; Gleditsoside B



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaomin Li, Wenhui Dong, Yanlin Yang, Shijing Ren, Xiangyu Wang, Meina Zou, Wen Lu, Lerong Liu, Yaoming Xue. Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells. In vitro cellular & developmental biology. Animal. 2023 Oct; 59(9):684-696. doi: 10.1007/s11626-023-00803-0. [PMID: 37831322]
  • Gwan Ui Hong, Jung-Yun Lee, Hanna Kang, Tae Yang Kim, Jae Yeo Park, Eun Young Hong, Youn Ho Shin, Sung Hoon Jung, Hung-Bae Chang, Young Ho Kim, Young-In Kwon, Jai Youl Ro. Inhibition of Osteoarthritis-Related Molecules by Isomucronulatol 7-O-β-d-glucoside and Ecliptasaponin A in IL-1β-Stimulated Chondrosarcoma Cell Model. Molecules (Basel, Switzerland). 2018 Oct; 23(11):. doi: 10.3390/molecules23112807. [PMID: 30380653]
  • Jing Zhao, Erwei Liu, Lifeng Han, Linlin Wang, Yi Zhang, Tao Wang, Shiming Fang, Xiumei Gao. Determination of ecliptasaponin A in rat plasma and tissues by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC. 2016 Jun; 30(6):846-51. doi: 10.1002/bmc.3617. [PMID: 26378987]
  • Xin-Yi You, Qian Xue, Yue Fang, Qianyu Liu, Chao Feng Zhang, Ceng Zhao, Mian Zhang, Xiang-Hong Xu. Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice. Journal of ethnopharmacology. 2015 Dec; 175(?):172-80. doi: 10.1016/j.jep.2015.08.034. [PMID: 26385580]
  • Feng-Min Xi, Chun-Tong Li, Jun Han, Shi-Shan Yu, Zhi-Jun Wu, Wan-Sheng Chen. Thiophenes, polyacetylenes and terpenes from the aerial parts of Eclipata prostrate. Bioorganic & medicinal chemistry. 2014 Nov; 22(22):6515-22. doi: 10.1016/j.bmc.2014.06.051. [PMID: 25443644]