Ginsenoside Rh3 (BioDeep_00000230479)

 

Secondary id: BioDeep_00000019019, BioDeep_00000894320

PANOMIX_OTCML-2023


代谢物信息卡片


(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2Z)-6-methylhepta-2,5-dien-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol

化学式: C36H60O7 (604.4338809999999)
中文名称: 异人参皂苷 Rh3, 异人参皂苷Rh3, 人参皂苷 Rh3, 人参皂苷Rh3, 异人参皂苷RH3, 人参皂苷 RH3
谱图信息: 最多检出来源 Viridiplantae(plant) 0.42%

分子结构信息

SMILES: CC(=CCC=C(C)C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)C
InChI: InChI=1S/C36H60O7/c1-20(2)10-9-11-21(3)22-12-16-36(8)28(22)23(38)18-26-34(6)15-14-27(33(4,5)25(34)13-17-35(26,36)7)43-32-31(41)30(40)29(39)24(19-37)42-32/h10-11,22-32,37-41H,9,12-19H2,1-8H3/b21-11-/t22-,23-,24-,25+,26-,27+,28+,29-,30+,31-,32+,34+,35-,36-/m1/s1

描述信息

Ginsenoside Rh3 is a triterpenoid saponin.
Ginsenoside Rh3 is a natural product found in Panax ginseng and Panax notoginseng with data available.
Annotation level-1

同义名列表

5 个代谢物同义名

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2Z)-6-methylhepta-2,5-dien-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol; beta-D-Glucopyranoside, (3beta,12beta,20Z)-12-hydroxydammara-20(22),24-dien-3-yl; Isoginsenoside Rh3; Ginsenoside Rh3; 2-({16-hydroxy-2,6,6,10,11-pentamethyl-14-[(2Z)-6-methylhepta-2,5-dien-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yingchao Wu, Dajin Pi, Shuyao Zhou, Zhongjia Yi, Yangyang Dong, Wuhong Wang, Huan Ye, Yiliu Chen, Qian Zuo, Mingzi Ouyang. Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells. Acta biochimica et biophysica Sinica. 2023 Apr; 55(4):587-600. doi: 10.3724/abbs.2023068. [PMID: 37092860]
  • Ting Yang, Wenwu Xu, Xiyu Wei, Zhenzhen Zhang, Yue Sun, Houru Liu, Peihua Yu, Wei Li, Dehong Yu. Determination of ginsenoside Rh3 in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomedical chromatography : BMC. 2022 Feb; 36(2):e5268. doi: 10.1002/bmc.5268. [PMID: 34676576]
  • Xiu-Mei Wang, Chang She, Quan Li, Di Zhang, Jin-Xia Xu, Min-Hui Li, Ping Li, Hong-Bin Xu. Ginsenoside Rh3 activates Nrf2 signaling and protects endometrial cells from oxygen and glucose deprivation-reoxygenation. Aging. 2020 04; 12(7):6109-6119. doi: 10.18632/aging.103009. [PMID: 32259797]
  • Eun-Jin Kim, Il-Hoon Jung, Thi Kim Van Le, Jin-Ju Jeong, Nam-Jae Kim, Dong-Hyun Kim. Ginsenosides Rg5 and Rh3 protect scopolamine-induced memory deficits in mice. Journal of ethnopharmacology. 2013 Mar; 146(1):294-9. doi: 10.1016/j.jep.2012.12.047. [PMID: 23313392]