Tracheloside (BioDeep_00000230428)

 

Secondary id: BioDeep_00000021942

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(3S,4S)-4-(3,4-Dimethoxybenzyl)-3-hydroxy-3-(3-methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl)dihydrofuran-2(3H)-one

化学式: C27H34O12 (550.2050164)
中文名称: 络石苷
谱图信息: 最多检出来源 Viridiplantae(plant) 21.43%

分子结构信息

SMILES: COC1=C(C=C(C=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)OC)O)OC
InChI: InChI=1S/C27H34O12/c1-34-17-6-4-14(9-19(17)35-2)8-16-13-37-26(32)27(16,33)11-15-5-7-18(20(10-15)36-3)38-25-24(31)23(30)22(29)21(12-28)39-25/h4-7,9-10,16,21-25,28-31,33H,8,11-13H2,1-3H3

描述信息

Tracheloside is a glycoside and a lignan. It has a role as a metabolite.
Tracheloside is a natural product found in Carthamus oxyacanthus, Trachelospermum asiaticum, and other organisms with data available.
A natural product found particularly in Carthamus tinctorius and Trachelospermum.
Tracheloside is an antiestrogenic lignin. Tracheloside promotes keratinocyte proliferation through ERK1/2 stimulation. Tracheloside is a good candidate to promote wound healing[1].
Tracheloside is an antiestrogenic lignin. Tracheloside promotes keratinocyte proliferation through ERK1/2 stimulation. Tracheloside is a good candidate to promote wound healing[1].

同义名列表

13 个代谢物同义名

(3S,4S)-4-(3,4-Dimethoxybenzyl)-3-hydroxy-3-(3-methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl)dihydrofuran-2(3H)-one; (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]oxolan-2-one; 2(3H)-FURANONE, 4-((3,4-DIMETHOXYPHENYL)METHYL)-3-((4-(.BETA.-D-GLUCOPYRANOSYLOXY)-3-METHOXYPHENYL)METHYL)DIHYDRO-3-HYDROXY-, (3S,4S)-; 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-3-hydroxy-, (3S-cis)-; (3S,4S)-4-((3,4-DIMETHOXYPHENYL)METHYL)-3-((4-(.BETA.-D-GLUCOPYRANOSYLOXY)-3-METHOXYPHENYL)METHYL)DIHYDRO-3-HYDROXY-2(3H)-FURANONE; 2(3H)-Furanone,4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(b-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-3-hydroxy-,(3S,4S)-; 4-({4-[(3,4-Dimethoxyphenyl)methyl]-3-hydroxy-2-oxooxolan-3-yl}methyl)-2-methoxyphenyl hexopyranoside; 8-HYDROXYARCTIGENIN-4-O-.BETA.-D-GLUCOSIDE; UNII-CU15UC170Q; Tracheloside; CU15UC170Q; 4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(3-methoxy-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl]oxolan-2-one; (-)-Tracheloside



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hee Soon Shin, Min-Jung Bae, Sun Young Jung, Hye-Jeong See, Yun Tai Kim, Jeong-Ryong Do, Su Yeon Back, Sang-Won Choi, Dong-Hwa Shon. Enhancing Effect of Trachelogenin from Trachelospermi caulis Extract on Intestinal Barrier Function. Biological & pharmaceutical bulletin. 2015; 38(11):1707-13. doi: 10.1248/bpb.b15-00332. [PMID: 26268064]
  • Lilla Szokol-Borsodi, Anna Sólyomváry, Ibolya Molnár-Perl, Imre Boldizsár. Optimum yields of dibenzylbutyrolactone-type lignans from Cynareae fruits, during their ripening, germination and enzymatic hydrolysis processes, determined by on-line chromatographic methods. Phytochemical analysis : PCA. 2012 Nov; 23(6):598-603. doi: 10.1002/pca.2360. [PMID: 22396124]
  • Li Li, Fanhua Meng, Jifen Guo, Lu Sun, Nengjiang Yu, Yimin Zhao. Simultaneous quantification of tracheloside and trachelogenin in rat plasma using liquid chromatography/tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 May; 879(15-16):1033-7. doi: 10.1016/j.jchromb.2011.02.021. [PMID: 21482203]
  • I Boldizsár, M Kraszni, F Tóth, B Noszál, I Molnár-Perl. Complementary fragmentation pattern analysis by gas chromatography-mass spectrometry and liquid chromatography tandem mass spectrometry confirmed the precious lignan content of Cirsium weeds. Journal of chromatography. A. 2010 Oct; 1217(40):6281-9. doi: 10.1016/j.chroma.2010.08.018. [PMID: 20813375]
  • Hye Hyun Yoo, Jeong Hill Park, Sung Won Kwon. An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius. Bioscience, biotechnology, and biochemistry. 2006 Nov; 70(11):2783-5. doi: 10.1271/bbb.60290. [PMID: 17090940]
  • Zhong-jie Zou, Jun-shan Yang, Jian-hua Ju. [Studies on the chemical constituents in herbs of Hemistepta lyrata]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 May; 31(10):812-3. doi: ". [PMID: 17048662]
  • Yasuki Kitamura, Megumi Yamagishi, Kazushi Okazaki, Hwa-Young Son, Takayoshi Imazawa, Akiyoshi Nishikawa, Toshio Iwata, Yoshie Yamauchi, Masaaki Kasai, Kentaro Tsutsumi, Masao Hirose. Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats. Cancer letters. 2003 Oct; 200(2):133-9. doi: 10.1016/s0304-3835(03)00281-7. [PMID: 14568166]
  • M Nose, T Fujimoto, S Nishibe, Y Ogihara. Structural transformation of lignan compounds in rat gastrointestinal tract; II. Serum concentration of lignans and their metabolites. Planta medica. 1993 Apr; 59(2):131-4. doi: 10.1055/s-2006-959627. [PMID: 8387675]