Yangabin (BioDeep_00000230249)

Main id: BioDeep_00000002926

 

PANOMIX_OTCML-2023


代谢物信息卡片


1H,3H-Furo(3,4-c)furan, tetrahydro-1,4-bis(3,4,5)-trimethoxyphenyl)-, 1alpha,3aalpha,4alpha,6aalpha)-

化学式: C24H30O8 (446.194058)
中文名称: 鹅掌楸树脂酚B二甲醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=CC(=C1OC)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC)OC
InChI: InChI=1S/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21+,22+/m0/s1



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

29 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Jéssica Rebouças-Silva, Gabriel Farias Santos, José Maria Barbosa Filho, Andresa A Berretta, Franciane Marquele-Oliveira, Valéria M Borges. In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez. Frontiers in cellular and infection microbiology. 2022; 12(?):1045732. doi: 10.3389/fcimb.2022.1045732. [PMID: 36704104]
  • María Y Rios, Yordin D Ocampo-Acuña, M Ángeles Ramírez-Cisneros, María E Salazar-Rios. Furofuranone Lignans from Leucophyllum ambiguum. Journal of natural products. 2020 05; 83(5):1424-1431. doi: 10.1021/acs.jnatprod.9b00759. [PMID: 32239935]
  • Júlia Martins, Joana Coelho, Maraine Catarina Tadini, Rebeca Oliveira de Souza, Sonia Aparecida Figueiredo, Maria José Vieira Fonseca, Nayara Cristina Perez de Albuquerque, Norberto Peporine Lopes, Andresa Berretta, Franciane Marquele-Oliveira, Anderson Rodrigo Moraes de Oliveira. Yangambin and Epi-yangambin Isomers: New Purification Method from Ocotea fasciculata and First Cytotoxic Aspects Focusing on In Vivo Safety. Planta medica. 2020 Apr; 86(6):415-424. doi: 10.1055/a-1118-3828. [PMID: 32126582]
  • Ramesh Kumar Santhanam, Syahida Ahmad, Faridah Abas, Intan Safinar Ismail, Yaya Rukayadi, Muhammad Tayyab Akhtar, Khozirah Shaari. Bioactive Constituents of Zanthoxylum rhetsa Bark and Its Cytotoxic Potential against B16-F10 Melanoma Cancer and Normal Human Dermal Fibroblast (HDF) Cell Lines. Molecules (Basel, Switzerland). 2016 May; 21(6):. doi: 10.3390/molecules21060652. [PMID: 27231889]
  • Rubens L Monte Neto, Louisa M A Sousa, Celidarque S Dias, José M Barbosa Filho, Márcia R Oliveira, Regina C B Q Figueiredo. Morphological and physiological changes in Leishmania promastigotes induced by yangambin, a lignan obtained from Ocotea duckei. Experimental parasitology. 2011 Jan; 127(1):215-21. doi: 10.1016/j.exppara.2010.07.020. [PMID: 20691682]
  • Jae Yeon Kim, Hyo Jin Lim, Da Yeon Lee, Ji Sun Kim, Do Hee Kim, Hwa Jin Lee, Hee Doo Kim, Raok Jeon, Jae-Ha Ryu. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorganic & medicinal chemistry letters. 2009 Feb; 19(3):937-40. doi: 10.1016/j.bmcl.2008.11.103. [PMID: 19110419]
  • Rubens L Monte Neto, Louisa M A Sousa, Celidarque S Dias, José M Barbosa Filho, Márcia R Oliveira. Yangambin cytotoxicity: a pharmacologically active lignan obtained from Ocotea duckei vattimo (Lauraceae). Zeitschrift fur Naturforschung. C, Journal of biosciences. 2008 Sep; 63(9-10):681-6. doi: 10.1515/znc-2008-9-1012. [PMID: 19040107]
  • Rubens L Neto Monte, José M Filho Barbosa, Louisa M A Sousa, Petrônio F Filho Athayde, Celidarque S Dias, Márcia R Oliveira. Crude ethanolic extract, lignoid fraction and yangambin from Ocotea duckei (Lauraceae) show antileishmanial activity. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2007 May; 62(5-6):348-52. doi: 10.1515/znc-2007-5-605. [PMID: 17708438]
  • Marise Maleck de Oliveira Cabral, Paloma Martins Mendonça, Celma Marinho da Silva Gomes, José Maria Barbosa-Filho, Celidarque da Silva Dias, Maurilio José Soares, Margareth Maria de Carvalho Queiroz. Biological activity of yangambin on the postembryonic development of Chrysomya megacephala (Diptera: Calliphoridae). Journal of medical entomology. 2007 Mar; 44(2):249-55. doi: 10.1603/0022-2585(2007)44[249:baoyot]2.0.co;2. [PMID: 17427693]
  • Regina Célia Pereira Marques, Sílvia Regina Batistuzzo de Medeiros, Celidarque da Silva Dias, José Maria Barbosa-Filho, Lucymara Fassarella Agnez-Lima. Evaluation of the mutagenic potential of yangambin and of the hydroalcoholic extract of Ocotea duckei by the Ames test. Mutation research. 2003 Apr; 536(1-2):117-20. doi: 10.1016/s1383-5718(03)00040-8. [PMID: 12694751]
  • C V Araújo, J M Barbosa-Filho, R S Cordeiro, E Tibiriçá. Protective effects of yangambin on cardiovascular hyporeactivity to catecholamines in rats with endotoxin-induced shock. Naunyn-Schmiedeberg's archives of pharmacology. 2001 Mar; 363(3):267-75. doi: 10.1007/s002100000350. [PMID: 11284440]
  • E Tibiriçá. Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants. Cardiovascular drug reviews. 2001; 19(4):313-28. doi: 10.1111/j.1527-3466.2001.tb00073.x. [PMID: 11830750]
  • C M Jesus-Morais, E F Assis, R S Cordeiro, J M Barbosa-Filho, W T Lima, Z L Silva, P T Bozza, H C Castro-Faria-Neto. Yangambin, a lignan obtained from Ocotea duckei, differentiates putative PAF receptor subtypes in the gastrointestinal tract of rats. Planta medica. 2000 Apr; 66(3):211-6. doi: 10.1055/s-2000-8556. [PMID: 10821044]
  • S Cailleaux, R A Lopes-Martins, F Aimbire, R S Cordeiro, E Tibiriçá. Involvement of platelet-activating factor in the modulation of vascular tone in the isolated perfused rabbit kidney. Naunyn-Schmiedeberg's archives of pharmacology. 1999 Jun; 359(6):505-11. doi: 10.1007/pl00005383. [PMID: 10431763]
  • J M Herbert, H C Castro-Faria-Neto, J M Barbosa-Filho, R S Cordeiro, E Tibiriça. Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin. Journal of lipid mediators and cell signalling. 1997 Sep; 17(1):1-14. doi: 10.1016/s0929-7855(97)00011-4. [PMID: 9302650]
  • M F Serra, B L Diaz, E O Barreto, A P Pereira, M C Lima, J M Barbosa-Filho, R S Cordeiro, M A Martins, P M de Silva. Anti-allergic properties of the natural PAF antagonist yangambin. Planta medica. 1997 Jun; 63(3):207-12. doi: 10.1055/s-2006-957654. [PMID: 9225600]
  • H C Castro-Faria-Neto, C V Araújo, S Moreira, P T Bozza, G Thomas, J M Barbosa-Filho, R S Cordeiro, E V Tibiriçá. Yangambin: a new naturally-occurring platelet-activating factor receptor antagonist: in vivo pharmacological studies. Planta medica. 1995 Apr; 61(2):106-12. doi: 10.1055/s-2006-958026. [PMID: 7753914]
  • H C Castro-Faria-Neto, P T Bozza, H N Cruz, C L Silva, F A Violante, J M Barbosa-Filho, G Thomas, M A Martins, E V Tibiriçá, F Noel. Yangambin: a new naturally-occurring platelet-activating factor receptor antagonist: binding and in vitro functional studies. Planta medica. 1995 Apr; 61(2):101-5. doi: 10.1055/s-2006-958025. [PMID: 7753913]
  • H C Castro-Faria-Neto, M A Martins, P M Silva, P T Bozza, H N Cruz, M de Queiroz-Paulo, M A Kaplan, R S Cordeiro. Pharmacological profile of epiyangambin: a furofuran lignan with PAF antagonist activity. Journal of lipid mediators. 1993 May; 7(1):1-9. doi: . [PMID: 8358020]