Gaultherin (BioDeep_00000230243)

   

PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


methyl 2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxybenzoate

化学式: C19H26O12 (446.1424)
中文名称: 冬绿苷
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 98.81%

分子结构信息

SMILES: COC(=O)C1=CC=CC=C1OC2C(C(C(C(O2)COC3C(C(C(CO3)O)O)O)O)O)O
InChI: InChI=1S/C19H26O12/c1-27-17(26)8-4-2-3-5-10(8)30-19-16(25)14(23)13(22)11(31-19)7-29-18-15(24)12(21)9(20)6-28-18/h2-5,9,11-16,18-25H,6-7H2,1H3/t9-,11-,12+,13-,14+,15-,16-,18+,19-/m1/s1

描述信息

Gaultherin is a glycoside.
Gaultherin is a natural product found in Gaultheria procumbens, Monotropa hypopitys, and other organisms with data available.
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin[1].

同义名列表

16 个代谢物同义名

methyl 2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxybenzoate; BENZOIC ACID, 2-((6-O-.BETA.-D-XYLOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-, METHYL ESTER; 2-((6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy) benzoic acid methyl ester; methylsalicylate O-beta-D-xylopyranosyl-(1->6)-O-beta-D-glucopyranoside; METHYL 2-O-.BETA.-D-XYLOSYL-(1->6)-.BETA.-D-GLUCOPYRANOSYLSALICYLATE; METHYL SALICYLATE .BETA.-PRIMEVEROSIDE; methylsalicylate beta-primeveroside; methylsalicylate-GX; MONOTROPITOSIDE; GAULTHERIN [MI]; Monotropitosid; Monotropeoside; MEGxp0_000158; Monotropitin; ACon1_000261; Gaultherin



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Fiaz Alam, Muhammad Hanif, Asad Ur Rahman, Sayyad Ali, Saeed Jan. In vitro, in vivo and in silico evaluation of analgesic, anti-inflammatory, and anti-pyretic activity of salicylate rich fraction from Gaultheria trichophylla Royle (Ericaceae). Journal of ethnopharmacology. 2023 Jan; 301(?):115828. doi: 10.1016/j.jep.2022.115828. [PMID: 36240979]
  • Silvia Carlin, Domenico Masuero, Graziano Guella, Urska Vrhovsek, Fulvio Mattivi. Methyl Salicylate Glycosides in Some Italian Varietal Wines. Molecules (Basel, Switzerland). 2019 Sep; 24(18):. doi: 10.3390/molecules24183260. [PMID: 31500198]
  • Bin Zhang, Xiao-Li He, Yi Ding, Guan-Hua Du. Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. European journal of pharmacology. 2006 Jan; 530(1-2):166-71. doi: 10.1016/j.ejphar.2005.11.030. [PMID: 16375889]
  • . . . . doi: . [PMID: 23956261]