Rosarin (BioDeep_00000230194)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2R,3R,4S,5S,6R)-2-(cinnamyloxy)-6-((((2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol

化学式: C20H28O10 (428.16823880000004)
中文名称: 洛塞琳, 络塞琳
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)COC3C(C(C(O3)CO)O)O)O)O)O
InChI: InChI=1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1

描述信息

Rosarin is an O-acyl carbohydrate.
Rosarin is a natural product found in Rhodiola rosea, Rhodiola crenulata, and other organisms with data available.
See also: Sedum roseum root (part of).
Rosarin is a cinnamyl alcohol?glycoside isolated from?Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1?β, and TNF- α in the kidney and prefrontal cortex of brain in mice?[1].
Rosarin is a cinnamyl alcohol?glycoside isolated from?Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1?β, and TNF- α in the kidney and prefrontal cortex of brain in mice?[1].

同义名列表

13 个代谢物同义名

(2R,3R,4S,5S,6R)-2-(cinnamyloxy)-6-((((2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol; (2R,3S,4S,5R,6R)-2-[[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol; .BETA.-D-GLUCOPYRANOSIDE, (2E)-3-PHENYL-2-PROPEN-1-YL 6-O-.ALPHA.-L-ARABINOFURANOSYL-; beta-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-o-alpha-L-arabinofuranosyl-; b-D-Glucopyranoside,(2E)-3-phenyl-2-propen-1-yl 6-O-a-L-arabinofuranosyl-; Rosarin (constituent of rhodiola rosea) [DSC]; Rosarin (constituent of rhodiola rosea); Rosarin, >=98\\% (HPLC); Rosarin (glycoside); UNII-PQA54L0KFI; Rosarin, (-)-; PQA54L0KFI; Rosarin



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Andrey S Marchev, Petya Dimitrova, Ivanka K Koycheva, Milen I Georgiev. Altered expression of TRAIL on mouse T cells via ERK phosphorylation by Rhodiola rosea L. and its marker compounds. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Oct; 108(Pt B):419-428. doi: 10.1016/j.fct.2017.02.009. [PMID: 28189478]
  • E A Elewa, M A El Tokhy, S E Fathy, A M Talaat. Predictive role of urinary neutrophil gelatinase-associated lipocalin in lupus nephritis. Lupus. 2015 Feb; 24(2):138-46. doi: 10.1177/0961203314550225. [PMID: 25199807]
  • Marta Grech-Baran, Katarzyna Sykłowska-Baranek, Anna Krajewska-Patan, Anna Wyrwał, Agnieszka Pietrosiuk. Biotransformation of cinnamyl alcohol to rosavins by non-transformed wild type and hairy root cultures of Rhodiola kirilowii. Biotechnology letters. 2014 Mar; 36(3):649-56. doi: 10.1007/s10529-013-1401-5. [PMID: 24190481]
  • Yuan-Chun Ma, Xiao-Qiang Wang, Feifei Hou, Jie Ma, Mai Luo, Shane Lu, Peter Jin, Alice Chen, Iris Xu, Asmita V Patel, Derek Gorecki. Simultaneous quantification of polyherbal formulations containing Rhodiola rosea L. and Eleutherococcus senticosus Maxim. using rapid resolution liquid chromatography (RRLC). Journal of pharmaceutical and biomedical analysis. 2011 Jul; 55(5):908-15. doi: 10.1016/j.jpba.2011.03.013. [PMID: 21466940]
  • Yuan-Chun Ma, Xiao-Qiang Wang, Fei Fei Hou, Jie Ma, Mai Luo, Shane Lu, Peter Jin, Nelly Terevsky, Alice Chen, Iris Xu, Asmita V Patel, Dariusz Gorecki. Rapid resolution liquid chromatography (RRLC) analysis for quality control of Rhodiola rosea roots and commercial standardized products. Natural product communications. 2011 May; 6(5):645-50. doi: ". [PMID: 21615025]
  • A Panossian, N Nikoyan, N Ohanyan, A Hovhannisyan, H Abrahamyan, E Gabrielyan, G Wikman. Comparative study of Rhodiola preparations on behavioral despair of rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2008 Jan; 15(1-2):84-91. doi: 10.1016/j.phymed.2007.10.003. [PMID: 18054474]