Ungeremine (BioDeep_00000229857)

   

Volatile Flavor Compounds natural product


代谢物信息卡片


17-hydroxy-5,7-dioxa-12|E?-azapentacyclo[10.6.1.0?,??.0?,?.0??,??]nonadeca-1(18),2,4(8),9,11,15(19),16-heptaen-12-ylium

化学式: C16H12NO3+ (266.08171419999996)
中文名称: 石蒜碱内铵盐, 氧化石蒜碱
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 17.07%

分子结构信息

SMILES: C1C[N+]2=CC3=CC4=C(C=C3C5=CC(=CC1=C52)O)OCO4
InChI: InChI=1S/C16H11NO3/c18-11-3-9-1-2-17-7-10-4-14-15(20-8-19-14)6-12(10)13(5-11)16(9)17/h3-7H,1-2,8H2/p+1

描述信息

Ungeremine is a natural product found in Crinum americanum, Crinum asiaticum, and other organisms with data available.

同义名列表

22 个代谢物同义名

17-hydroxy-5,7-dioxa-12|E?-azapentacyclo[10.6.1.0?,??.0?,?.0??,??]nonadeca-1(18),2,4(8),9,11,15(19),16-heptaen-12-ylium; 5,7-dioxa-12-azoniapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-1(18),2,4(8),9,11,15(19),16-heptaen-17-ol; [1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinium, 4,5-dihydro-2-hydroxy-; (1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridinium, 4,5-dihydro-2-hydroxy-; 4,5-Dihydro-2-hydroxy-(1,3)dioxolo(4,5-j)pyrrolo(3.2.1-de)phenanthridinium; 4,5-Dihydro-2-hydroxy-(1,3)dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridinium; 2-hydroxy-4H,5H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-6-ium; Lycoranium, 1,2,3,3a,6,7,12b,12c-octadehydro-2-hydroxy-; 1,2,3,3a,6,7,12b,12c-Octadehydro-2-hydroxylycoranium; ungeremine, acetate salt; Ungeremine (Lycobetaine); Lycobetaine（Ungeremine）; LycobetaineUngeremine; lycobetaine acetate; ungeremine chloride; UNII-9EVC5B2RPS; NCI60_002978; Lycobetaine; Ungeremine; 9EVC5B2RPS; Ungerimine; Ungeremine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Deepali Katoch, Dharmesh Kumar, Yogendra S Padwad, Bikram Singh, Upendra Sharma. Pseudolycorine N-oxide, a new N-oxide from Narcissus tazetta. Natural product research. 2020 Jul; 34(14):2051-2058. doi: 10.1080/14786419.2019.1574785. [PMID: 30784301]
  • Baofang Zhang, Zilin Chen. Screening of cathepsin B inhibitors in traditional Chinese medicine by capillary electrophoresis with immobilized enzyme microreactor. Journal of pharmaceutical and biomedical analysis. 2019 Nov; 176(?):112811. doi: 10.1016/j.jpba.2019.112811. [PMID: 31437748]
  • Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete, Pierre Tane, Thomas Efferth. Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Jul; 60(?):152832. doi: 10.1016/j.phymed.2019.152832. [PMID: 31031043]
  • Tijia Chen, Ting Gong, Ting Zhao, Yao Fu, Zhirong Zhang, Tao Gong. A comparison study between lycobetaine-loaded nanoemulsion and liposome using nRGD as therapeutic adjuvant for lung cancer therapy. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2018 Jan; 111(?):293-302. doi: 10.1016/j.ejps.2017.09.041. [PMID: 28966099]
  • Tijia Chen, Wenhao Li, Ting Gong, Yao Fu, Rui Ding, Tao Gong, Zhirong Zhang. Analysis of Lycobetaine in Rat Plasma by LC-ESI-MS/MS. Journal of chromatographic science. 2017 03; 55(3):301-308. doi: 10.1093/chromsci/bmw185. [PMID: 27903551]
  • Zhi-Ming Liu, Xiao-Yun Huang, Mao-Rong Cui, Xiao-De Zhang, Zhao Chen, Ben-Shou Yang, Xiao-Kun Zhao. Amaryllidaceae alkaloids from the bulbs of Lycoris radiata with cytotoxic and anti-inflammatory activities. Fitoterapia. 2015 Mar; 101(?):188-93. doi: 10.1016/j.fitote.2015.01.003. [PMID: 25596094]
  • Simone A Baechler, Markus Fehr, Michael Habermeyer, Andreas Hofmann, Karl-Heinz Merz, Heinz-Herbert Fiebig, Doris Marko, Gerhard Eisenbrand. Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs. Bioorganic & medicinal chemistry. 2013 Feb; 21(3):814-23. doi: 10.1016/j.bmc.2012.11.011. [PMID: 23266176]
  • Hui Zhao, Hua Lu, Tao Gong, Zhirong Zhang. Nanoemulsion loaded with lycobetaine-oleic acid ionic complex: physicochemical characteristics, in vitro, in vivo evaluation, and antitumor activity. International journal of nanomedicine. 2013; 8(?):1959-73. doi: 10.2147/ijn.s43892. [PMID: 23723698]
  • In Kyung Rhee, Natalie Appels, Bertil Hofte, Bahadir Karabatak, Cornelis Erkelens, Lucy M Stark, Lee A Flippin, Robert Verpoorte. Isolation of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay system. Biological & pharmaceutical bulletin. 2004 Nov; 27(11):1804-9. doi: 10.1248/bpb.27.1804. [PMID: 15516727]
  • C C Huang, C S Han, X F Yue, C M Shen, S W Wang, F G Wu, B Xu. Cytotoxicity and sister chromatid exchanges induced in vitro by six anticancer drugs developed in the People's Republic of China. Journal of the National Cancer Institute. 1983 Oct; 71(4):841-7. doi: . [PMID: 6413744]