2-Hydroxy-4-methoxybenzaldehyde (BioDeep_00000229769)
Secondary id: BioDeep_00000864187
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C8H8O3 (152.0473)
中文名称: 4-甲氧基水杨醛, 2-羟基-4-甲氧基苯甲醛
谱图信息:
最多检出来源 Macaca mulatta(otcml) 100%
分子结构信息
SMILES: COC1=CC(=C(C=C1)C=O)O
InChI: InChI=1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3
描述信息
2-Hydroxy-4-methoxybenzaldehyde is a member of methoxybenzenes and a member of phenols.
2-Hydroxy-4-methoxybenzaldehyde is a natural product found in Tarenna attenuata, Juglans nigra, and other organisms with data available.
2-hydroxy-4-methoxybenzaldehyde, also known as 4-methoxysalicylaldehyde or 2-hydroxy-P-anisaldehyde, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. 2-hydroxy-4-methoxybenzaldehyde is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 2-hydroxy-4-methoxybenzaldehyde is a vanillin tasting compound found in black walnut, which makes 2-hydroxy-4-methoxybenzaldehyde a potential biomarker for the consumption of this food product. 2-hydroxy-4-methoxybenzaldehyde is a chemical compound and an isomer of vanillin. Urolithin M7, one of the urolithins, has also been synthesized from 2-hydroxy-4-methoxybenzaldehyde using the inverse electron-demand Diels–Alder reaction .
2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2].
2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2].
同义名列表
30 个代谢物同义名
InChI=1/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H; 4-08-00-01754 (Beilstein Handbook Reference); 2-Hydroxy-4-methoxybenzaldehyde, 98\\%; Benzaldehyde, 2-hydroxy-4-methoxy-; 2-hydroxy-4-methoxy benzaldehyde; 4-methoxy-2-hydroxy-benzaldehyde; 2-hydroxyl-4-methoxybenzaldehyde; 2-Hydroxy-4-methoxy-benzaldehyde; 4-methoxy-2-hydroxybenzaldehyde; o-Hydroxy-p-methoxybenzaldehyde; 2-Hydroxy-4-methoxybenazldehyde; 2-Hydroxy-4-methoxybenzaldehyde; 4-methoxy-6-hydroxybenzaldehyde; 2-hydroxy-4methoxybenzaldehyde; 2-hydroxy4methoxybenzaldehyde; 4-Methoxysalicylaldehyde,(S); Salicylaldehyde, 4-methoxy-; 4-o-Methylresorcylaldehyde; p-Anisaldehyde, 2-hydroxy-; 4-METHOXY SALICYLAIDEHYDE; 2-hydroxy-p-anisaldehyde; ghl.PD_Mitscher_leg0.298; 2-Formyl-5-methoxyphenol; 4-methoxysalicylaldehyde; 4-Methoxysalicyaldehyde; 2-hydroxyanisaldehyde; UNII-2N395P88LW; 2N395P88LW; AI3-38507; 2-Hydroxy-4-methoxybenzaldehyde
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:183274
- PubChem: 69600
- ChEMBL: CHEMBL350966
- Wikipedia: 2-Hydroxy-4-methoxybenzaldehyde
- MeSH: 2-hydroxy-4-methoxybenzaldehyde
- ChemIDplus: 0000673223
- foodb: FDB005824
- chemspider: 62803
- CAS: 673-22-3
- medchemexpress: HY-N0445
- PMhub: MS000189587
- LOTUS: LTS0030238
- wikidata: Q15634116
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Vereena Rodrigues, Amit Kumar, Kamasamudra N Prabhu, V S Pragadheesh, Ashutosh K Shukla, Velusamy Sundaresan. Adventitious root cultures of Decalepis salicifolia for the production of 2-hydroxy-4-methoxybenzaldehyde, a vanillin isomer flavor metabolite.
Applied microbiology and biotechnology.
2021 Apr; 105(8):3087-3099. doi:
10.1007/s00253-021-11262-6
. [PMID: 33829315] - Vereena Rodrigues, Amit Kumar, Sivaraman Gokul, Ashutosh K Shukla, Kaliamoorthy Ravikumar, Velusamy Sundaresan. Decalepis salicifolia (Bedd. ex Hook. f.) Venter: A steno-endemic and critically endangered medicinal and aromatic plant from Western Ghats, India.
Journal of biosciences.
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Applied microbiology and biotechnology.
2019 Aug; 103(16):6747-6758. doi:
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. [PMID: 31230099] - Kiran Kamireddy, Salim Chinnu, P S Priyanka, P S Rajini, Parvatam Giridhar. Neuroprotective effect of Decalepis hamiltonii aqueous root extract and purified 2-hydroxy-4-methoxy benzaldehyde on 6-OHDA induced neurotoxicity in Caenorhabditis elegans.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Sep; 105(?):997-1005. doi:
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. [PMID: 30021395] - Nanishankar V Harohally, Chris Cherita, Praveena Bhatt, K A Anu Appaiah. Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2-Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes.
Journal of agricultural and food chemistry.
2017 Oct; 65(40):8773-8778. doi:
10.1021/acs.jafc.7b02576
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European journal of medicinal chemistry.
2016 May; 114(?):209-19. doi:
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"
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. [PMID: 24841455] - Anish Kundu, Adinpunya Mitra. Flavoring extracts of Hemidesmus indicus roots and Vanilla planifolia pods exhibit in vitro acetylcholinesterase inhibitory activities.
Plant foods for human nutrition (Dordrecht, Netherlands).
2013 Sep; 68(3):247-53. doi:
10.1007/s11130-013-0363-z
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Plant physiology and biochemistry : PPB.
2012 Jul; 56(?):104-8. doi:
10.1016/j.plaphy.2012.04.005
. [PMID: 22609460] - Eun-Young Jeong, Kyoung-Shik Cho, Hoi-Seon Lee. Food protective effects of Periploca sepium oil and its active component against stored food mites.
Journal of food protection.
2012 Jan; 75(1):118-22. doi:
10.4315/0362-028x.jfp-11-315
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2011 Oct; 3(4):225-31. doi:
10.4103/0974-8490.89741
. [PMID: 22224044] - Carmela Fimognari, Monia Lenzi, Lorenzo Ferruzzi, Eleonora Turrini, Paolo Scartezzini, Ferruccio Poli, Roberto Gotti, Alessandra Guerrini, Giovanni Carulli, Virginia Ottaviano, Giorgio Cantelli-Forti, Patrizia Hrelia. Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug.
PloS one.
2011; 6(6):e21544. doi:
10.1371/journal.pone.0021544
. [PMID: 21738701] - R Harish, T Shivanandappa. Hepatoprotective potential of Decalepis hamiltonii (Wight and Arn) against carbon tetrachloride-induced hepatic damage in rats.
Journal of pharmacy & bioallied sciences.
2010 Oct; 2(4):341-5. doi:
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Molecules (Basel, Switzerland).
2010 Aug; 15(8):5807-17. doi:
10.3390/molecules15085807
. [PMID: 20736908] - M Gayathri, K Kannabiran. Effect of 2-Hydroxy-4-Methoxy Benzoic Acid from the Roots of Hemidesmus indicus on Streptozotocin-induced Diabetic Rats.
Indian journal of pharmaceutical sciences.
2009 Sep; 71(5):581-5. doi:
10.4103/0250-474x.58180
. [PMID: 20502585] - Dipjyoti Chakraborty, Debabrata Sircar, Adinpunya Mitra. Phenylalanine ammonia-lyase-mediated biosynthesis of 2-hydroxy-4-methoxybenzaldehyde in roots of Hemidesmus indicus.
Journal of plant physiology.
2008 Jul; 165(10):1033-40. doi:
10.1016/j.jplph.2007.09.002
. [PMID: 18023917] - Jianxiao Shi, Tomoko Yamashita, Ayumi Todo, Teruhiko Nitoda, Minoru Izumi, Naomichi Baba, Shuhei Nakajima. Repellent from traditional Chinese medicine, Periploca sepium Bunge.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2007 Nov; 62(11-12):821-5. doi:
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. [PMID: 18274284] - Chao-Bin Xue, Li Zhang, Wan-Chun Luo, Xian-Ye Xie, Lin Jiang, Ting Xiao. 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.
Bioorganic & medicinal chemistry.
2007 Mar; 15(5):2006-15. doi:
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. [PMID: 17258462] - K N Chidambara Murthy, T Rajasekaran, P Giridhar, G A Ravishankar. Antioxidant property of Decalepis hamiltonii Wight & Arn.
Indian journal of experimental biology.
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"
. [PMID: 17131914] - R Harish, S Divakar, Anup Srivastava, T Shivanandappa. Isolation of antioxidant compounds from the methanolic extract of the roots of Decalepis hamiltonii (Wight and Arn.).
Journal of agricultural and food chemistry.
2005 Oct; 53(20):7709-14. doi:
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. [PMID: 16190621] - P Giridhar, T Rajasekaran, S Nagarajan, G A Ravishankar. Production of 2-hydroxy-4-methoxybenzaldehyde in roots of tissue culture raised and acclimatized plants of Decalepis hamiltonii Wight & Arn., an endangered shrub endemic to Southern India and evaluation of its performance vis-a-vis plants from natural habitat.
Indian journal of experimental biology.
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. [PMID: 15274490] - Subban Nagarajan, Lingamallu Jagan Mohan Rao. Determination of 2-hydroxy-4-methoxybenzaldehyde in roots of Decalepis hamiltonii (Wight & Arn.) and Hemidesmus indicus R.Br.
Journal of AOAC International.
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