3-(3-hydroxyphenyl)-3-hydroxypropionic acid (BioDeep_00000229591)

   

human metabolite


代谢物信息卡片


3-(3-hydroxyphenyl)-3-hydroxypropionic acid

化学式: C9H10O4 (182.057906)
中文名称: β-(间羟基苯基)羟丙烯酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC(=C1)O)C(CC(=O)O)O
InChI: InChI=1S/C9H10O4/c10-7-3-1-2-6(4-7)8(11)5-9(12)13/h1-4,8,10-11H,5H2,(H,12,13)

描述信息

A dihydroxy monocarboxylic acid that is 3-hydroxypropanoic acid substituted by a 3-hydroxyphenyl group at position 3.

同义名列表

2 个代谢物同义名

3-(3-hydroxyphenyl)-3-hydroxypropionic acid; 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jin-Ran Chen, Haijun Zhao, Umesh D Wankhade, Sree V Chintapalli, Can Li, Dongzheng Gai, Kartik Shankar, Fenghuang Zhan, Oxana P Lazarenko. GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice. Communications biology. 2021 01; 4(1):53. doi: 10.1038/s42003-020-01564-2. [PMID: 33420329]
  • Coco Chu, Mitchell H Murdock, Deqiang Jing, Tae Hyung Won, Hattie Chung, Adam M Kressel, Tea Tsaava, Meghan E Addorisio, Gregory G Putzel, Lei Zhou, Nicholas J Bessman, Ruirong Yang, Saya Moriyama, Christopher N Parkhurst, Anfei Li, Heidi C Meyer, Fei Teng, Sangeeta S Chavan, Kevin J Tracey, Aviv Regev, Frank C Schroeder, Francis S Lee, Conor Liston, David Artis. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019 10; 574(7779):543-548. doi: 10.1038/s41586-019-1644-y. [PMID: 31645720]
  • Xiyue Xiong, Dan Liu, Yichao Wang, Ting Zeng, Ying Peng. Urinary 3-(3-Hydroxyphenyl)-3-hydroxypropionic Acid, 3-Hydroxyphenylacetic Acid, and 3-Hydroxyhippuric Acid Are Elevated in Children with Autism Spectrum Disorders. BioMed research international. 2016; 2016(?):9485412. doi: 10.1155/2016/9485412. [PMID: 27123458]
  • Recep Keşli, Cem Gökçen, Ufuk Buluğ, Yüksel Terzi. Investigation of the relation between anaerobic bacteria genus clostridium and late-onset autism etiology in children. Journal of immunoassay & immunochemistry. 2014; 35(1):101-9. doi: 10.1080/15321819.2013.792834. [PMID: 24063620]
  • Doris M Jacobs, Laura Spiesser, Maxime Garnier, Niels de Roo, Ferdi van Dorsten, Boudewijn Hollebrands, Ewoud van Velzen, Richard Draijer, John van Duynhoven. SPE-NMR metabolite sub-profiling of urine. Analytical and bioanalytical chemistry. 2012 Nov; 404(8):2349-61. doi: 10.1007/s00216-012-6339-2. [PMID: 22932811]
  • Daniele Del Rio, Angelique Stalmach, Luca Calani, Alan Crozier. Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols. Nutrients. 2010 08; 2(8):820-33. doi: 10.3390/nu2080820. [PMID: 22254058]
  • William Shaw. Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutritional neuroscience. 2010 Jun; 13(3):135-43. doi: 10.1179/147683010x12611460763968. [PMID: 20423563]
  • Suri Roowi, William Mullen, Christine A Edwards, Alan Crozier. Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans. Molecular nutrition & food research. 2009 May; 53 Suppl 1(?):S68-75. doi: 10.1002/mnfr.200800287. [PMID: 19415668]
  • P F Gulyassy, A T Bottini, L A Stanfel, E A Jarrard, T A Depner. Isolation and chemical identification of inhibitors of plasma ligand binding. Kidney international. 1986 Sep; 30(3):391-8. doi: 10.1038/ki.1986.197. [PMID: 3784282]
  • P F Gulyassy, A T Bottini, E A Jarrard, L A Stanfel. Isolation of inhibitors of ligand: albumin-binding from uremic body fluids and normal urine. Kidney international. Supplement. 1983 Dec; 16(?):S238-42. doi: NULL. [PMID: 6588258]