Potassium triphosphate (K5(P3O10)) (BioDeep_00000228233)

   

human metabolite


代谢物信息卡片


pentapotassium bis(phosphonatooxy)phosphinate

化学式: K5O10P3 (447.688979)
中文名称: 三聚磷酸钾
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: [K+].[K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O
InChI: /p-5

描述信息

Food contaminant derived from its use as a boiler water additive for the prepn. of steam used in food processing. Texturiser and sequestrant in foods, mainly as the K/Na double salt. PPPi is a salt or acid that contains three phosphate groups ; ; Triphosphoric acid, also tripolyphosphoric acid, with formula H5P3O10, is a condensed form of phosphoric acid.In polyphosphoric acids, it is the next after pyrophosphoric acid, H4P2O7, also called diphosphoric acid.Compounds such as ATP (adenosine triphosphate) are esters of triphosphoric acid.; ; Polyphosphates are hydrolyzed into smaller units (orthophosphates) in the gut before absorption, which may induce a metabolic acidosis. The acute toxicity of polyphosphonates is low as the lowest LD50 after oral administration is > 1,000 mg/kg body weight.Polyphosphates are moderately irritating to skin and mucous membrane because of their alkalinity.; ; No mutagenic potential was observed when TTP was tested in a Salmonella/microsome assay (Ames test) and in a chromosomal aberration assay in vitro using a Chinese hamster fibroblast cell line (Ishidate et al. 1984). Tetrasodium pyrophosphate was not mutagenic in an in vitro assay using S. cerevisiae strains and S. typhimurium strains with and without the addition of mammalian metabolic activation preparations (IPCS 1982).; ; Reproduction studies in three generations of rats on diets with 0.5\\% TTP were performed. TTP had no effects on fertility or litter size, or on growth or survival on offspring (Hodge 1964). Tetrasodi
Food contaminant derived from its use as a boiler water additive for the prepn. of steam used in food processing. Texturiser and sequestrant in foods, mainly as the K/Na double salt

同义名列表

18 个代谢物同义名

pentapotassium bis(phosphonatooxy)phosphinate; Triphosphoric acid, sodium, potassium salt; Potassium triphosphoric acid (K5(P3O10)); Triphosphoric acid, pentapotassium salt; Triphosphoric acid, 99TC-labeled CPD; Triphosphoric acid, pentasodium salt; Potassium triphosphate (K5(P3O10)); Pentapotassium triphosphoric acid; Sodium tripolyphosphate anhydrous; Triphosphoric acid, sodium salt; Tetrasodium tripolyphosphate; Pentapotassium triphosphate; Sodium tripolyphosphate; Potassium triphosphate; Sodium triphosphate; Triphosphoric acid; Tripolyphosphate; Triphosphate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mahesh Tiran Gunasena, Mohd Zobir Hussein, Asgar Ali, Mohd Aswad Abdul Wahab, Abdulaziz Bashir Kutawa, Amara Rafif, Syazwan Afif Mohd Zobir, Khairulmazmi Ahmad. Zingiber officinale Roscoe Essential Oils-Loaded Chitosan Nanoparticles with Enhanced Bactericidal Efficacy against Burkholderia glumae in Rice. Chemistry & biodiversity. 2023 Dec; 20(12):e202300686. doi: 10.1002/cbdv.202300686. [PMID: 37905394]
  • Malahat Mojarab-Mahboubkar, Zahra Afrazeh, Roya Azizi, Jalal Jalali Sendi. Efficiency of Artemisia annua L. essential oil and its chitosan/tripolyphosphate or zeolite encapsulated form in controlling Sitophilus oryzae L. Pesticide biochemistry and physiology. 2023 Sep; 195(?):105544. doi: 10.1016/j.pestbp.2023.105544. [PMID: 37666615]
  • Lori Manoukian, Robin S Stein, José A Correa, Dominic Frigon, Sidney Omelon. Short-chain polyphosphates: Extraction effects on migration and size estimation of Saccharomyces cerevisiae extracts with polyacrylamide gel electrophoresis. Electrophoresis. 2023 08; 44(15-16):1197-1205. doi: 10.1002/elps.202300055. [PMID: 37353918]
  • Qiaohua Yan, Meiqing Li, Liying Dong, Jie Luo, Xiaohui Zhong, Fei Shi, Gang Ye, Ling Zhao, Hualin Fu, Gang Shu, Xinghong Zhao, Wei Zhang, Hongmei Yin, Yinglun Li, Huaqiao Tang. Preparation, characterization and protective effect of chitosan - Tripolyphosphate encapsulated dihydromyricetin nanoparticles on acute kidney injury caused by cisplatin. International journal of biological macromolecules. 2023 Jun; 245(?):125569. doi: 10.1016/j.ijbiomac.2023.125569. [PMID: 37369257]
  • Yu-Rui Feng, Ting-Ting Li, Shi-Jia Wang, Ying-Tang Lu, Ting-Ting Yuan. Triphosphate Tunnel Metalloenzyme 2 Acts as a Downstream Factor of ABI4 in ABA-Mediated Seed Germination. International journal of molecular sciences. 2023 May; 24(10):. doi: 10.3390/ijms24108994. [PMID: 37240339]
  • Brittny N Blakely, John Agnew, Charlotte Gard, Alvaro Romero. Effects of blood meal source on blood consumption and reproductive success of cat fleas, Ctenocephalides felis. PLoS neglected tropical diseases. 2023 04; 17(4):e0011233. doi: 10.1371/journal.pntd.0011233. [PMID: 37053346]
  • Ali Hanafi, Kazem D Safa, Shamsali Rezazadeh. Neural Network-based Optimization of Silybum Marianum Extract-loaded Chitosan Particles: Modeling, Preparation and Antioxidant Evaluation. Current computer-aided drug design. 2023; 19(1):2-12. doi: 10.2174/1573409918666221010101036. [PMID: 36221887]
  • Nargis Parvin Laha, Ricardo F H Giehl, Esther Riemer, Danye Qiu, Naga Jyothi Pullagurla, Robin Schneider, Yashika Walia Dhir, Ranjana Yadav, Yeshambel Emewodih Mihiret, Philipp Gaugler, Verena Gaugler, Haibin Mao, Ning Zheng, Nicolaus von Wirén, Adolfo Saiardi, Saikat Bhattacharjee, Henning J Jessen, Debabrata Laha, Gabriel Schaaf. INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis. Plant physiology. 2022 11; 190(4):2722-2738. doi: 10.1093/plphys/kiac425. [PMID: 36124979]
  • Marta Pesquera, Jacobo Martinez, Benoît Maillot, Kai Wang, Manuel Hofmann, Pierre Raia, Sylvain Loubéry, Priscille Steensma, Michael Hothorn, Teresa B Fitzpatrick. Structural and functional studies of Arabidopsis thaliana triphosphate tunnel metalloenzymes reveal roles for additional domains. The Journal of biological chemistry. 2022 11; 298(11):102438. doi: 10.1016/j.jbc.2022.102438. [PMID: 36049521]
  • Wei Liu, Chunxia G Cronin, Ziming Cao, Chengliang Wang, Jianbin Ruan, Sunitha Pulikkot, Alexxus Hall, Hao Sun, Alex Groisman, Yunfeng Chen, Anthony T Vella, Liang Hu, Bruce T Liang, Zhichao Fan. Nexinhib20 Inhibits Neutrophil Adhesion and β2 Integrin Activation by Antagonizing Rac-1-Guanosine 5'-Triphosphate Interaction. Journal of immunology (Baltimore, Md. : 1950). 2022 10; 209(8):1574-1585. doi: 10.4049/jimmunol.2101112. [PMID: 36165184]
  • Hyeon Jeong Lee, Se-Rin Kim, Jea Young Park, Eun Young Park. Phytate-mediated phosphorylation of starch by dry heating with rice bran extract. Carbohydrate polymers. 2022 Apr; 282(?):119104. doi: 10.1016/j.carbpol.2022.119104. [PMID: 35123757]
  • Sara A Abosabaa, Mona G Arafa, Aliaa Nabil ElMeshad. Hybrid chitosan-lipid nanoparticles of green tea extract as natural anti-cellulite agent with superior in vivo potency: full synthesis and analysis. Drug delivery. 2021 Dec; 28(1):2160-2176. doi: 10.1080/10717544.2021.1989088. [PMID: 34623203]
  • Marwa Hasanein Asfour, Abeer A A Salama, Amira Mohamed Mohsen. Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats. Journal of pharmaceutical sciences. 2021 09; 110(9):3208-3220. doi: 10.1016/j.xphs.2021.05.007. [PMID: 34015278]
  • Magali Leonel, Marília S Del Bem, Thaís P R Dos Santos, Célia Maria Landi Franco. Preparation and properties of phosphate starches from tuberous roots. International journal of biological macromolecules. 2021 Jul; 183(?):898-907. doi: 10.1016/j.ijbiomac.2021.05.045. [PMID: 33971226]
  • Henry Pertinez, Rajith K R Rajoli, Saye H Khoo, Andrew Owen. Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2. The Journal of antimicrobial chemotherapy. 2021 07; 76(8):2121-2128. doi: 10.1093/jac/dkab135. [PMID: 34075418]
  • Wen-Juan Hu, Lu Chang, Ying Yang, Xin Wang, Yuan-Chao Xie, Jing-Shan Shen, Bo Tan, Jia Liu. Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice. Acta pharmacologica Sinica. 2021 Jul; 42(7):1195-1200. doi: 10.1038/s41401-020-00537-9. [PMID: 33041326]
  • J Sandhya, S Veeralakshmi, S Kalaiselvam. Tripolyphosphate crosslinked Triticum aestivum (wheatgrass) functionalized antimicrobial chitosan: Ameliorating effect on physicochemical, mechanical, invitro cytocompatibility and cell migration properties. Journal of biomolecular structure & dynamics. 2021 Mar; 39(5):1635-1644. doi: 10.1080/07391102.2020.1736160. [PMID: 32107986]
  • Scott W Mueller, Tyree H Kiser, Taylor Morrisette, Martin R Zamora, Dennis M Lyu, Jennifer J Kiser. Ribavirin and cellular ribavirin-triphosphate concentrations in blood and bronchoalveolar lavage fluid in two lung transplant patients with respiratory syncytial virus. Transplant infectious disease : an official journal of the Transplantation Society. 2021 Feb; 23(1):e13464. doi: 10.1111/tid.13464. [PMID: 32920958]
  • Ashutosh Gupta, Amit Kumar Singh, Mariam Loka, Abhay Kumar Pandey, Anupam Bishayee. Ferulic acid-mediated modulation of apoptotic signaling pathways in cancer. Advances in protein chemistry and structural biology. 2021; 125(?):215-257. doi: 10.1016/bs.apcsb.2020.12.005. [PMID: 33931140]
  • Pollen K Yeung, Sheyda Mohammadizadeh, Fatemeh Akhoundi, Kelsey Mann, Remigius U Agu, Thomas Pulinilkunnil. Hemodynamic Assessment and In vivo Catabolism of Adenosine 5'-triphosphate in Doxorubicin or Isoproterenol-induced Cardiovascular Toxicity. Drug metabolism letters. 2021; 14(1):80-88. doi: 10.2174/1872312814666201022103802. [PMID: 33092518]
  • Inseob Choi, Qixin Zhong. Physicochemical properties of skim milk powder dispersions prepared with calcium-chelating sodium tripolyphosphate, trisodium citrate, and sodium hexametaphosphate. Journal of dairy science. 2020 Nov; 103(11):9868-9880. doi: 10.3168/jds.2020-18644. [PMID: 32861487]
  • Kasra Yari, Iman Akbari, Seyed Ali Vaziri Yazdi. Development and evaluation of sodium alginate-basil seeds mucilage beads as a suitable carrier for controlled release of metformin. International journal of biological macromolecules. 2020 Sep; 159(?):1-10. doi: 10.1016/j.ijbiomac.2020.04.111. [PMID: 32330501]
  • Birol Kılıç, Azim Şimşek, James R Claus, Esra Karaca, Damla Bilecen. Effects of partial and complete replacement of added phosphates with encapsulated phosphates on lipid oxidation inhibition in cooked ground meat during storage. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2020 Apr; 26(3):213-221. doi: 10.1177/1082013219881519. [PMID: 31604384]
  • McKenna J Powell, Joseph G Sebranek, Kenneth J Prusa, Rodrigo Tarté. Evaluation of citrus fiber as a natural replacer of sodium phosphate in alternatively-cured all-pork Bologna sausage. Meat science. 2019 Nov; 157(?):107883. doi: 10.1016/j.meatsci.2019.107883. [PMID: 31284235]
  • Shufang Yang, Lei Dai, Like Mao, Jinfang Liu, Fang Yuan, Zaigui Li, Yanxiang Gao. Effect of sodium tripolyphosphate incorporation on physical, structural, morphological and stability characteristics of zein and gliadin nanoparticles. International journal of biological macromolecules. 2019 Sep; 136(?):653-660. doi: 10.1016/j.ijbiomac.2019.06.052. [PMID: 31195045]
  • Rajalakshmi Rukmangathen, Indira Muzib Yallamalli, Prasanna Raju Yalavarthi. Formulation and biopharmaceutical evaluation of risperidone-loaded chitosan nanoparticles for intranasal delivery. Drug development and industrial pharmacy. 2019 Aug; 45(8):1342-1350. doi: 10.1080/03639045.2019.1619759. [PMID: 31094571]
  • Farhatun Najat Maluin, Mohd Zobir Hussein, Nor Azah Yusof, Sharida Fakurazi, Abu Seman Idris, Nur Hailini Zainol Hilmi, Leona Daniela Jeffery Daim. Preparation of Chitosan-Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm. Molecules (Basel, Switzerland). 2019 Jul; 24(13):. doi: 10.3390/molecules24132498. [PMID: 31288497]
  • Marzieh Rashidipour, Afshin Maleki, Sajad Kordi, Mehdi Birjandi, Naser Pajouhi, Ebrahim Mohammadi, Rouhollah Heydari, Reza Rezaee, Bahram Rasoulian, Behroz Davari. Pectin/Chitosan/Tripolyphosphate Nanoparticles: Efficient Carriers for Reducing Soil Sorption, Cytotoxicity, and Mutagenicity of Paraquat and Enhancing Its Herbicide Activity. Journal of agricultural and food chemistry. 2019 May; 67(20):5736-5745. doi: 10.1021/acs.jafc.9b01106. [PMID: 31042035]
  • Qian Wang, Jiayi Wang, Wu Ding, Dequan Zhang, Kevin Reed, Boce Zhang. Alternatives to carcinogenic preservatives in Chinese Sausage - Sorbic acid-loaded chitosan/tripolyphosphate nanoparticles. International journal of biological macromolecules. 2018 Dec; 120(Pt A):28-33. doi: 10.1016/j.ijbiomac.2018.08.034. [PMID: 30098368]
  • Deqing Xiao, Kah Hiing John Ling, Joseph Custodio, Sophia R Majeed, Thomas Tarnowski. Quantitation of intracellular triphosphate metabolites of antiretroviral agents in peripheral blood mononuclear cells (PBMCs) and corresponding cell count determinations: review of current methods and challenges. Expert opinion on drug metabolism & toxicology. 2018 Aug; 14(8):781-802. doi: 10.1080/17425255.2018.1500552. [PMID: 30010446]
  • Zi-Wei Jing, Min Luo, Yi-Yang Jia, Chen Li, Si-Yuan Zhou, Qi-Bing Mei, Bang-Le Zhang. Anti-Helicobacterpylori effectiveness and targeted delivery performance of amoxicillin-UCCs-2/TPP nanoparticles based on ureido-modified chitosan derivative. International journal of biological macromolecules. 2018 Aug; 115(?):367-374. doi: 10.1016/j.ijbiomac.2018.04.070. [PMID: 29660462]
  • Zbigniew Zawada, Ameneh Tatar, Pavle Mocilac, Miloš Buděšínský, Tomáš Kraus. Transport of Nucleoside Triphosphates into Cells by Artificial Molecular Transporters. Angewandte Chemie (International ed. in English). 2018 07; 57(31):9891-9895. doi: 10.1002/anie.201801306. [PMID: 29578619]
  • Chuhan Cheng, Cheng Liu, Bing Han, Zhijun Sun, Yutong Wang, Zhenshuai Li, Hong Mo, Jun Zhang. Silver Nanoparticles Modified with Sodium Triphosphate: Antibacterial Activity, Hemocompatibility and Cytotoxicity. Journal of nanoscience and nanotechnology. 2018 Jun; 18(6):3816-3824. doi: 10.1166/jnn.2018.15028. [PMID: 29442714]
  • Zhaohan Liu, Yunfeng Hu, Xia Li, Zhouxiong Mei, Shi Wu, Yong He, Xinwei Jiang, Jianxia Sun, Jianbo Xiao, Liehua Deng, Weibin Bai. Nanoencapsulation of Cyanidin-3- O-glucoside Enhances Protection Against UVB-Induced Epidermal Damage through Regulation of p53-Mediated Apoptosis in Mice. Journal of agricultural and food chemistry. 2018 May; 66(21):5359-5367. doi: 10.1021/acs.jafc.8b01002. [PMID: 29732888]
  • Sandra Rojas-Moreno, Guillermo Osorio-Revilla, Tzayhrí Gallardo-Velázquez, Fernando Cárdenas-Bailón, Gabriela Meza-Márquez. Effect of the cross-linking agent and drying method on encapsulation efficiency of orange essential oil by complex coacervation using whey protein isolate with different polysaccharides. Journal of microencapsulation. 2018 Mar; 35(2):165-180. doi: 10.1080/02652048.2018.1449910. [PMID: 29513057]
  • Ignacio M Helbling, Carlos A Busatto, Silvana A Fioramonti, Juan I Pesoa, Liliana Santiago, Diana A Estenoz, Julio A Luna. Preparation of TPP-crosslinked chitosan microparticles by spray drying for the controlled delivery of progesterone intended for estrus synchronization in cattle. Pharmaceutical research. 2018 Feb; 35(3):66. doi: 10.1007/s11095-018-2363-z. [PMID: 29464352]
  • Hung-Ling Hsieh, Chia-Hung Lee, Kuo-Chih Lin. Development of Yam Dioscorin-Loaded Nanoparticles for Paracellular Transport Across Human Intestinal Caco-2 Cell Monolayers. Journal of agricultural and food chemistry. 2018 Feb; 66(5):1175-1183. doi: 10.1021/acs.jafc.7b04150. [PMID: 29328647]
  • Pollen K Yeung, Chad Purcell, Fatemeh Akhoundi, Remigius U Agu. Adenosine and Adenosine 5'-triphosphate Catabolism in Systemic Blood as a Potential Biomarker for Doxorubicin Cardiotoxicity in an Experimental Rat Model in vivo. Cardiovascular & hematological disorders drug targets. 2018; 18(3):224-233. doi: 10.2174/1871529x18666180406125225. [PMID: 29623860]
  • Sohrab Ahmadivand, Mehdi Soltani, Mahdi Behdani, Øystein Evensen, Ehsan Alirahimi, Reza Hassanzadeh, Ellahe Soltani. Oral DNA vaccines based on CS-TPP nanoparticles and alginate microparticles confer high protection against infectious pancreatic necrosis virus (IPNV) infection in trout. Developmental and comparative immunology. 2017 09; 74(?):178-189. doi: 10.1016/j.dci.2017.05.004. [PMID: 28479343]
  • Huoi Ung, Purva Karia, Kazuo Ebine, Takashi Ueda, Keiko Yoshioka, Wolfgang Moeder. Triphosphate Tunnel Metalloenzyme Function in Senescence Highlights a Biological Diversification of This Protein Superfamily. Plant physiology. 2017 Sep; 175(1):473-485. doi: 10.1104/pp.17.00700. [PMID: 28733390]
  • Dongdong Yuan, Jean Christophe Jacquier, E Dolores O'Riordan. Entrapment of protein in chitosan-tripolyphosphate beads and its release in an in vitro digestive model. Food chemistry. 2017 Aug; 229(?):495-501. doi: 10.1016/j.foodchem.2017.02.107. [PMID: 28372206]
  • Daniele Y Nakasato, Anderson E S Pereira, Jhones L Oliveira, Halley C Oliveira, Leonardo F Fraceto. Evaluation of the effects of polymeric chitosan/tripolyphosphate and solid lipid nanoparticles on germination of Zea mays, Brassica rapa and Pisum sativum. Ecotoxicology and environmental safety. 2017 Aug; 142(?):369-374. doi: 10.1016/j.ecoenv.2017.04.033. [PMID: 28437729]
  • Mauricio T Jacques, Jhones L Oliveira, Estefânia V R Campos, Leonardo F Fraceto, Daiana Silva Ávila. Safety assessment of nanopesticides using the roundworm Caenorhabditis elegans. Ecotoxicology and environmental safety. 2017 May; 139(?):245-253. doi: 10.1016/j.ecoenv.2017.01.045. [PMID: 28160702]
  • Teresa Cerchiara, Angela Abruzzo, Rogers Alberto Ñahui Palomino, Beatrice Vitali, Renata De Rose, Giuseppe Chidichimo, Luca Ceseracciu, Athanassia Athanassiou, Bruno Saladini, Francesco Dalena, Federica Bigucci, Barbara Luppi. Spanish Broom (Spartium junceum L.) fibers impregnated with vancomycin-loaded chitosan nanoparticles as new antibacterial wound dressing: Preparation, characterization and antibacterial activity. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2017 Mar; 99(?):105-112. doi: 10.1016/j.ejps.2016.11.028. [PMID: 27931851]
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  • Martijn Fenaux, Xiaodong Lin, Fumiaki Yokokawa, Zachary Sweeney, Oliver Saunders, Lili Xie, Siew Pheng Lim, Marianne Uteng, Kyoko Uehara, Robert Warne, Wang Gang, Christopher Jones, Satya Yendluri, Helen Gu, Keith Mansfield, Julie Boisclair, Tycho Heimbach, Alexandre Catoire, Kathryn Bracken, Margaret Weaver, Heinz Moser, Weidong Zhong. Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk. Antimicrobial agents and chemotherapy. 2016 12; 60(12):7077-7085. doi: 10.1128/aac.01253-16. [PMID: 27645237]
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