Legumin (BioDeep_00000227722)
human metabolite
代谢物信息卡片
Disodium 4-(2,4-dichlorophenoxy)butanoic acid 4-(4-chloro-2-methylphenoxy)butanoic acid
化学式: C21H21Cl3Na2O6 (520.0199056)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C=CC(=C1)Cl)OCCCC(=O)[O-].C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)[O-].[Na+].[Na+]
InChI: /q
描述信息
Legumin can be found in common pea, which makes legumin a potential biomarker for the consumption of this food product. Legumin, or vegetable casein, is a protein substance analogous to the casein of milk, obtained from beans, peas, lentils, vetches, hemp (specifically edestin) and other leguminous seeds. It is a globulin and structurally similar to the 11S globulin family .
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相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Hu, Li-Ping Zhu, Rui-Qi Wang, Lixia Zhu, Feng Chen, Yibo Hou, Kang Ni, Shasha Deng, Siyu Liu, Wantao Ying, Jin-Lyu Sun, Hong Li, Tengchuan Jin. Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin.
Journal of agricultural and food chemistry.
2024 Apr; 72(14):8189-8199. doi:
10.1021/acs.jafc.4c00351. [PMID: 38551197] - S Kabasser, C Radauer, E Eber, M E Haber, K Hieden, P Zieglmayer, L E Kost, S B Sindher, S Chinthrajah, S Geiselhart, K Hoffmann-Sommergruber, K C Nadeau, H Breiteneder, M Bublin. Cosensitization to the 3 Nonhomologous Major Cashew Allergens Ana o 1, Ana o 2, and Ana o 3 Is Caused by IgE Cross-reactivity.
Journal of investigational allergology & clinical immunology.
2024 Feb; 34(1):38-48. doi:
10.18176/jiaci.0867. [PMID: 36331131] - Seyed Mohammad Taghi Gharibzahedi, Brennan Smith, Zeynep Altintas. Bioactive and health-promoting properties of enzymatic hydrolysates of legume proteins: a review.
Critical reviews in food science and nutrition.
2024; 64(9):2548-2578. doi:
10.1080/10408398.2022.2124399. [PMID: 36200775] - Ahyeon Cho, Alpana Joshi, Hor-Gil Hur, Ji-Hoon Lee. Nodulation Experiment by Cross-Inoculation of Nitrogen-Fixing Bacteria Isolated from Root Nodules of Several Leguminous Plants.
Journal of microbiology and biotechnology.
2023 Dec; 34(3):1-10. doi:
10.4014/jmb.2310.10025. [PMID: 38213271] - Yu Duan, Ting Wang, Peixi Zhang, Xinjie Zhao, Jie Jiang, Yuanchun Ma, Xujun Zhu, Wanping Fang. The effect of intercropping leguminous green manure on theanine accumulation in the tea plant: A metagenomic analysis.
Plant, cell & environment.
2023 Dec; ?(?):. doi:
10.1111/pce.14784. [PMID: 38098148] - Tiffany Amat, Ali Assifaoui, Christophe Schmitt, Rémi Saurel. Importance of binary and ternary complex formation on the functional and nutritional properties of legume proteins in presence of phytic acid and calcium.
Critical reviews in food science and nutrition.
2023 Nov; 63(33):12036-12058. doi:
10.1080/10408398.2022.2098247. [PMID: 35852135] - Yuzhu Zhang, Shilpa R Bhardwaj, Shu-Chen Lyu, Sharon Chinthrajah, Kari C Nadeau, Caiming Li. Expression, purification, characterization, and patient IgE reactivity of new macadamia nut iso-allergen.
Protein expression and purification.
2023 03; 203(?):106211. doi:
10.1016/j.pep.2022.106211. [PMID: 36462715] - Hui Wen Lee, Yuyun Lu, Yuyu Zhang, Caili Fu, Dejian Huang. Physicochemical and functional properties of red lentil protein isolates from three origins at different pH.
Food chemistry.
2021 Oct; 358(?):129749. doi:
10.1016/j.foodchem.2021.129749. [PMID: 33933978] - Zhongqi He, Christopher P Mattison, Dunhua Zhang, Casey C Grimm. Vicilin and legumin storage proteins are abundant in water and alkali soluble protein fractions of glandless cottonseed.
Scientific reports.
2021 04; 11(1):9209. doi:
10.1038/s41598-021-88527-7. [PMID: 33911142] - Daniel Żmudziński, Urszula Goik, Paweł Ptaszek. Functional and Rheological Properties of Vicia faba L. Protein Isolates.
Biomolecules.
2021 01; 11(2):. doi:
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Biomolecules.
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Food chemistry.
2019 Sep; 293(?):299-306. doi:
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Critical reviews in biotechnology.
2018 Feb; 38(1):47-67. doi:
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Journal of proteomics.
2017 10; 169(?):143-152. doi:
10.1016/j.jprot.2017.06.009. [PMID: 28634118] - Yu-Zhu Zhang, Wen-Xian Du, Yuting Fan, Jiang Yi, Shu-Chen Lyu, Kari C Nadeau, Andrew L Thomas, Tara McHugh. Purification and Characterization of a Black Walnut (Juglans nigra) Allergen, Jug n 4.
Journal of agricultural and food chemistry.
2017 Jan; 65(2):454-462. doi:
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Protein and peptide letters.
2017; 24(3):267-277. doi:
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Protoplasma.
2016 Mar; 253(2):517-30. doi:
10.1007/s00709-015-0830-5. [PMID: 25994087] - A S Rudakova, A M Cherdivară, K A Wilson, A D Shutov. Seed Storage Globulins: Origin and Evolution of Primary and Higher Order Structures.
Biochemistry. Biokhimiia.
2015 Oct; 80(10):1354-61. doi:
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Colloids and surfaces. B, Biointerfaces.
2015 Aug; 132(?):45-53. doi:
10.1016/j.colsurfb.2015.04.065. [PMID: 26005930] - B Cabanillas, N Novak. Allergic Reactions to Pine Nut: A Review.
Journal of investigational allergology & clinical immunology.
2015; 25(5):329-33. doi:
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Journal of the science of food and agriculture.
2014 Jan; 94(2):280-7. doi:
10.1002/jsfa.6250. [PMID: 23744804] - Young-Min Goo, Tae-Won Kim, Min-Kyung Lee, Shin-Woo Lee. Accumulation of PrLeg, a Perilla legumin protein in potato tuber results in enhanced level of sulphur-containing amino acids.
Comptes rendus biologies.
2013 Sep; 336(9):433-9. doi:
10.1016/j.crvi.2013.09.002. [PMID: 24161240] - Shimrit Bar-El Dadon, Cristina Yolanda Pascual, Dani Eshel, Paula Teper-Bamnolker, María Dolores Paloma Ibáñez, Ram Reifen. Vicilin and the basic subunit of legumin are putative chickpea allergens.
Food chemistry.
2013 May; 138(1):13-8. doi:
10.1016/j.foodchem.2012.10.031. [PMID: 23265449] - Guangfang Guo, Dongwen Lv, Xing Yan, Saminathan Subburaj, Pei Ge, Xiaohui Li, Yingkao Hu, Yueming Yan. Proteome characterization of developing grains in bread wheat cultivars (Triticum aestivum L.).
BMC plant biology.
2012 Aug; 12(?):147. doi:
10.1186/1471-2229-12-147. [PMID: 22900893] - Cécile Mertens, Lydie Dehon, Audrey Bourgeois, Christine Verhaeghe-Cartrysse, Christophe Blecker. Agronomical factors influencing the legumin/vicilin ratio in pea (Pisum sativum L.) seeds.
Journal of the science of food and agriculture.
2012 Jun; 92(8):1591-6. doi:
10.1002/jsfa.4738. [PMID: 22162104] - Girdhari M Sharma, Andre Irsigler, Pushparani Dhanarajan, Rosalia Ayuso, Luda Bardina, Hugh A Sampson, Kenneth H Roux, Shridhar K Sathe. Cloning and characterization of an 11S legumin, Car i 4, a major allergen in pecan.
Journal of agricultural and food chemistry.
2011 Sep; 59(17):9542-52. doi:
10.1021/jf2017447. [PMID: 21718052] - Michael Bourgeois, Françoise Jacquin, Florence Cassecuelle, Vincent Savois, Maya Belghazi, Grégoire Aubert, Laurence Quillien, Myriam Huart, Pascal Marget, Judith Burstin. A PQL (protein quantity loci) analysis of mature pea seed proteins identifies loci determining seed protein composition.
Proteomics.
2011 May; 11(9):1581-94. doi:
10.1002/pmic.201000687. [PMID: 21433288] - Subodh Gupta, Avinash Mishra, A K Verma, Ruchi Pandey, Laxmi Chand. Heterologous expression of legumin gene in E. coli isolated from cDNA clones of immature seeds of pigeonpea (Cajanus cajan L.).
Applied biochemistry and biotechnology.
2009 Jun; 157(3):377-94. doi:
10.1007/s12010-008-8276-2. [PMID: 18597049] - Xiaoyan Hao, Jiangui Li, Qinghua Shi, Jusong Zhang, Xiaoling He, Hao Ma. Characterization of a novel legumin alpha-amylase inhibitor from chickpea (Cicer arietinum L.) seeds.
Bioscience, biotechnology, and biochemistry.
2009 May; 73(5):1200-2. doi:
10.1271/bbb.80776. [PMID: 19420683] - Olivia Y Bässler, Julia Weiss, Stefanie Wienkoop, Karola Lehmann, Christian Scheler, Sabine Dölle, Dietmar Schwarz, Philipp Franken, Eckhard George, Margitta Worm, Wolfram Weckwerth. Evidence for novel tomato seed allergens: IgE-reactive legumin and vicilin proteins identified by multidimensional protein fractionation-mass spectrometry and in silico epitope modeling.
Journal of proteome research.
2009 Mar; 8(3):1111-22. doi:
10.1021/pr800186d. [PMID: 19203290] - Michael Bourgeois, Françoise Jacquin, Vincent Savois, Nicolas Sommerer, Valérie Labas, Céline Henry, Judith Burstin. Dissecting the proteome of pea mature seeds reveals the phenotypic plasticity of seed protein composition.
Proteomics.
2009 Jan; 9(2):254-71. doi:
10.1002/pmic.200700903. [PMID: 19086096] - Evelien L van Boxtel, Lambertus A M van den Broek, Stef J Koppelman, Harry Gruppen. Legumin allergens from peanuts and soybeans: effects of denaturation and aggregation on allergenicity.
Molecular nutrition & food research.
2008 Jun; 52(6):674-82. doi:
10.1002/mnfr.200700299. [PMID: 18338408] - M Le Gall, L Quillien, B Sève, J Guéguen, J P Lallès. Weaned piglets display low gastrointestinal digestion of pea (Pisum sativum L.) lectin and pea albumin 2.
Journal of animal science.
2007 Nov; 85(11):2972-81. doi:
10.2527/jas.2006-795. [PMID: 17565068] - S K Pramanik, A L Williams, J D Bewley. In vitro reconstitution of legumin (11S) mRNA and binding proteins as related to post-transcriptional regulation of protein synthesis in developing alfalfa embryos.
Cellular and molecular biology (Noisy-le-Grand, France).
2007 May; 53(3):64-73. doi:
". [PMID: 17531151] - Michiko Momma. A pepsin-resistant 20 kDa protein found in red kidney bean (Phaseolus vulgaris L.) identified as basic subunit of legumin.
Bioscience, biotechnology, and biochemistry.
2006 Dec; 70(12):3058-61. doi:
10.1271/bbb.60392. [PMID: 17151447] - E E Braudo, A N Danilenko, P V Guslyannikov, G O Kozhevnikov, G P Artykova, N A Lapteva, I A Vaintraub, E Sironi, M Duranti. Comparative effects of limited tryptic hydrolysis on physicochemical and structural features of seed 11S globulins.
International journal of biological macromolecules.
2006 Nov; 39(4-5):174-8. doi:
10.1016/j.ijbiomac.2005.12.006. [PMID: 16787660] - Mikhael Wallowitz, W Rich Peterson, Sandie Uratsu, Sarah S Comstock, Abhaya M Dandekar, Suzanne S Teuber. Jug r 4, a legumin group food allergen from walnut (Juglans regia Cv. Chandler).
Journal of agricultural and food chemistry.
2006 Oct; 54(21):8369-75. doi:
10.1021/jf061329s. [PMID: 17032053] - Takafumi Itoh, Roberta N Garcia, Motoyasu Adachi, Yukie Maruyama, Evelyn Mae Tecson-Mendoza, Bunzo Mikami, Shigeru Utsumi. Structure of 8Salpha globulin, the major seed storage protein of mung bean.
Acta crystallographica. Section D, Biological crystallography.
2006 Jul; 62(Pt 7):824-32. doi:
10.1107/s090744490601804x. [PMID: 16790939] - Emmanouil N Tzitzikas, Jean-Paul Vincken, Jolan de Groot, Harry Gruppen, Richard G F Visser. Genetic variation in pea seed globulin composition.
Journal of agricultural and food chemistry.
2006 Jan; 54(2):425-33. doi:
10.1021/jf0519008. [PMID: 16417300] - M Abirached-Darmency, M R Abdel-gawwad, G Conejero, J L Verdeil, R Thompson. In situ expression of two storage protein genes in relation to histo-differentiation at mid-embryogenesis in Medicago truncatula and Pisum sativum seeds.
Journal of experimental botany.
2005 Aug; 56(418):2019-28. doi:
10.1093/jxb/eri200. [PMID: 15983018] - Dirk Wenzel, Gaby Schauermann, Anke von Lüpke, Giselbert Hinz. The cargo in vacuolar storage protein transport vesicles is stratified.
Traffic (Copenhagen, Denmark).
2005 Jan; 6(1):45-55. doi:
10.1111/j.1600-0854.2004.00243.x. [PMID: 15569244] - Haruhiko Washida, Aya Sugino, Joachim Messing, Asim Esen, Thomas W Okita. Asymmetric localization of seed storage protein RNAs to distinct subdomains of the endoplasmic reticulum in developing maize endosperm cells.
Plant & cell physiology.
2004 Dec; 45(12):1830-7. doi:
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Plant physiology.
2004 Nov; 136(3):3457-66. doi:
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Journal of colloid and interface science.
2004 Oct; 278(1):71-80. doi:
10.1016/j.jcis.2004.05.039. [PMID: 15313639] - Francesca E O'Kane, Randolph P Happe, Johan M Vereijken, Harry Gruppen, Martinus A J S van Boekel. Heat-induced gelation of pea legumin: comparison with soybean glycinin.
Journal of agricultural and food chemistry.
2004 Aug; 52(16):5071-8. doi:
10.1021/jf035215h. [PMID: 15291477] - Alexander Zakharov, Martin Giersberg, Felicia Hosein, Michael Melzer, Klaus Müntz, Isolde Saalbach. Seed-specific promoters direct gene expression in non-seed tissue.
Journal of experimental botany.
2004 Jul; 55(402):1463-71. doi:
10.1093/jxb/erh158. [PMID: 15181101] - Heimo Breiteneder, Christian Radauer. A classification of plant food allergens.
The Journal of allergy and clinical immunology.
2004 May; 113(5):821-30; quiz 831. doi:
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Plant physiology and biochemistry : PPB.
2004 Feb; 42(2):157-63. doi:
10.1016/j.plaphy.2003.11.001. [PMID: 15283132] - Darren Gruis, Jan Schulze, Rudolf Jung. Storage protein accumulation in the absence of the vacuolar processing enzyme family of cysteine proteases.
The Plant cell.
2004 Jan; 16(1):270-90. doi:
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Journal of experimental botany.
2003 Jul; 54(388):1645-54. doi:
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Journal of plant physiology.
2003 Jun; 160(6):583-8. doi:
10.1078/0176-1617-00976. [PMID: 12872479] - Sangeeta Bharali, Nikhil K Chrungoo. Amino acid sequence of the 26 kDa subunit of legumin-type seed storage protein of common buckwheat (Fagopyrum esculentum Moench): molecular characterization and phylogenetic analysis.
Phytochemistry.
2003 May; 63(1):1-5. doi:
10.1016/s0031-9422(02)00755-0. [PMID: 12657290] - Tomomi Yamagata, Hisanao Kato, Satoshi Kuroda, Shunnosuke Abe, Eric Davies. Uncleaved legumin in developing maize endosperm: identification, accumulation and putative subcellular localization.
Journal of experimental botany.
2003 Mar; 54(384):913-22. doi:
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Journal of protein chemistry.
2003 Feb; 22(2):167-75. doi:
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Journal of drug targeting.
2002 Dec; 10(8):625-31. doi:
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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2002 Nov; 133(3):453-60. doi:
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Protoplasma.
2002 Oct; 220(1-2):97-103. doi:
10.1007/s00709-002-0025-8. [PMID: 12417941] - G O Kozhevnikov, A N Danilenko, E E Braudo, K D Schwenke. Comparative studies on thermodynamic characteristics of pea legumin and legumin-T thermal denaturation.
International journal of biological macromolecules.
2001 Dec; 29(4-5):225-36. doi:
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Die Nahrung.
2001 Oct; 45(6):382-4. doi:
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Die Nahrung.
2001 Oct; 45(6):377-81. doi:
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Die Nahrung.
2001 Oct; 45(6):385-7. doi:
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Current opinion in allergy and clinical immunology.
2001 Jun; 1(3):261-7. doi:
10.1097/01.all.0000011024.76416.01. [PMID: 11964699] - E Stöger, M Parker, P Christou, R Casey. Pea legumin overexpressed in wheat endosperm assembles into an ordered paracrystalline matrix.
Plant physiology.
2001 Apr; 125(4):1732-42. doi:
10.1104/pp.125.4.1732. [PMID: 11299354] - A Schlereth, D Standhardt, H P Mock, K Müntz. Stored cysteine proteinases start globulin mobilization in protein bodies of embryonic axes and cotyledons during vetch (Vicia sativa L.) seed germination.
Planta.
2001 Apr; 212(5-6):718-27. doi:
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Journal of agricultural and food chemistry.
2001 Mar; 49(3):1552-8. doi:
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International journal of biological macromolecules.
2001 Jan; 28(2):175-82. doi:
10.1016/s0141-8130(00)00167-7. [PMID: 11164235] - S Hillmer, A Movafeghi, D G Robinson, G Hinz. Vacuolar storage proteins are sorted in the cis-cisternae of the pea cotyledon Golgi apparatus.
The Journal of cell biology.
2001 Jan; 152(1):41-50. doi:
10.1083/jcb.152.1.41. [PMID: 11149919] - J P Krause, S Dudek, K D Schwenke. Changes in interfacial behaviour, emulsifying and foaming properties of faba bean legumin after modification with dimethylsuberimidate.
Die Nahrung.
2000 Dec; 44(6):403-6. doi:
10.1002/1521-3803(20001201)44:6<403::aid-food403>3.0.co;2-h. [PMID: 11190833] - M P Sales, I R Gerhardt, M F Grossi-De-Sá, J Xavier-Filho. Do legume storage proteins play a role in defending seeds against bruchids?.
Plant physiology.
2000 Oct; 124(2):515-22. doi:
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