Phenols (BioDeep_00000227323)
human metabolite Volatile Flavor Compounds
代谢物信息卡片
Dibenzo-1,4-thiazine
化学式: C12H9NS (199.04556739999998)
中文名称: 吩噻嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)NC3=CC=CC=C3S2
InChI: InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H
描述信息
In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of a hydroxyl group (-OH) bonded directly to an aromatic hydrocarbon group. The simplest of the class is phenol (C6H5OH). Phenols is found in many foods, some of which are tea, chinese cinnamon, ceylon cinnamon, and common thyme.
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:37932
- ChEBI: CHEBI:37931
- ChEBI: CHEBI:38093
- PubChem: 7108
- HMDB: HMDB0302434
- DrugBank: DB11447
- ChEMBL: CHEMBL828
- Wikipedia: Phenothiazine
- foodb: FDB004562
- chemspider: 21106365
- CAS: 75788-67-9
- CAS: 92-84-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Boyana Parvanova, Bilyana Tacheva, Ivan Ivanov. Prehemolytic impact of phenothiazine drugs on the attachment of spectrin network in red blood cells.
Folia medica.
2023 Oct; 65(5):783-787. doi:
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ChemMedChem.
2021 12; 16(24):3763-3771. doi:
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Cell reports.
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PloS one.
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
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Molecular immunology.
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10.1016/j.molimm.2019.04.008. [PMID: 31051313] - Wei-Bin Tseng, Ming-Mu Hsieh, Tai-Chia Chiu, Po-Lin Yu, Szu-Hua Chen. Enantioseparation of phenothiazines through capillary electrophoresis with solid phase extraction and polymer based stacking.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Jan; 877(1-2):37-42. doi:
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Drug metabolism and drug interactions.
2009; 24(2-4):137-51. doi:
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Acta histochemica.
2009; 111(4):329-33. doi:
10.1016/j.acthis.2008.11.010. [PMID: 19124148] - Natsuko Shinmen, Xiao-Pen Lee, Takeshi Kumazawa, Chika Hasegawa, Yasuhiro Ishiwata, Keizo Sato, Hiroshi Seno, Osamu Suzuki. Simultaneous determination of some phenothiazine derivatives in human blood by headspace solid-phase microextraction and gas chromatography with nitrogen-phosphorus detection.
Journal of AOAC International.
2008 Nov; 91(6):1354-62. doi:
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Archives of biochemistry and biophysics.
2008 Oct; 478(2):201-5. doi:
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Clinical chemistry.
2008 Sep; 54(9):1519-27. doi:
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Sudebno-meditsinskaia ekspertiza.
2008 Sep; 51(5):39-41. doi:
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Analytica chimica acta.
2008 Aug; 624(2):308-16. doi:
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Journal of psychopharmacology (Oxford, England).
2008 Mar; 22(2):119-27. doi:
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Bioorganic & medicinal chemistry.
2008 Feb; 16(3):1162-73. doi:
10.1016/j.bmc.2007.10.080. [PMID: 18024138] - Andrzej B Hendrich, Krystyna Michalak, Olga Wesołowska. Phase separation is induced by phenothiazine derivatives in phospholipid/sphingomyelin/cholesterol mixtures containing low levels of cholesterol and sphingomyelin.
Biophysical chemistry.
2007 Oct; 130(1-2):32-40. doi:
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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2007 Oct; 127(10):1621-42. doi:
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Biomacromolecules.
2007 Aug; 8(8):2576-85. doi:
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Archives of biochemistry and biophysics.
2007 May; 461(2):294-8. doi:
10.1016/j.abb.2007.02.029. [PMID: 17428437] - Yinhuan Li, Weifen Niu, Jiuru Lu. Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system.
Talanta.
2007 Feb; 71(3):1124-9. doi:
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Progress in neuro-psychopharmacology & biological psychiatry.
2007 Jan; 31(1):178-86. doi:
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Langmuir : the ACS journal of surfaces and colloids.
2007 Jan; 23(2):694-9. doi:
10.1021/la061628b. [PMID: 17209622] - Piotr Hydzik, Ewa Gomółka, Jolanta Wilimowska. [Extended suicidal poisoning with carbamazepine and phenothiazine derivatives].
Przeglad lekarski.
2007; 64(4-5):304-7. doi:
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Biochemical and biophysical research communications.
2006 Dec; 351(1):273-80. doi:
10.1016/j.bbrc.2006.10.039. [PMID: 17056009] - Stacy E F Melanson, Elizabeth Lee-Lewandrowski, David A Griggs, William H Long, James G Flood. Reduced interference by phenothiazines in amphetamine drug of abuse immunoassays.
Archives of pathology & laboratory medicine.
2006 Dec; 130(12):1834-8. doi:
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Current drug targets.
2006 Sep; 7(9):1095-105. doi:
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Biochemical pharmacology.
2006 Jul; 72(2):145-55. doi:
10.1016/j.bcp.2006.04.008. [PMID: 16729976] - Soumitra Ghosh, Pranit Kr Chaudhury, Hiranya K Goswami. An analysis of six cases of acute intermittent porphyria (AIP).
Indian journal of psychiatry.
2006 Jul; 48(3):189-92. doi:
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Chemical & pharmaceutical bulletin.
2006 Jul; 54(7):972-6. doi:
10.1248/cpb.54.972. [PMID: 16819214] - Weifen Niu, Na Feng, Fei Nie, Jiuru Lu. Investigating the post-chemiluminescence behavior of phenothiazine medications in the luminol-potassium ferricyanide system: molecular imprinting-post-chemiluminescence method for the determination of chlorpromazine hydrochloride.
Analytical and bioanalytical chemistry.
2006 May; 385(1):153-60. doi:
10.1007/s00216-006-0365-x. [PMID: 16547741] - Chen Song, Holm Holmsen, Willy Nerdal. Existence of lipid microdomains in bilayer of dipalmitoyl phosphatidylcholine (DPPC) and 1-stearoyl-2-docosahexenoyl phosphatidylserine (SDPS) and their perturbation by chlorpromazine: a 13C and 31P solid-state NMR study.
Biophysical chemistry.
2006 Apr; 120(3):178-87. doi:
10.1016/j.bpc.2005.11.007. [PMID: 16356624] - Oliver H Wittekindt, Alexander Schmitz, Frank Lehmann-Horn, Wolfram Hänsel, Stephan Grissmer. The human Ca2+-activated K+ channel, IK, can be blocked by the tricyclic antihistamine promethazine.
Neuropharmacology.
2006 Mar; 50(4):458-67. doi:
10.1016/j.neuropharm.2005.10.005. [PMID: 16310228] - Ewa Kleszczewska, Jolanta Hejza, Tomasz Kleszczewski. [Determination of cadmium level in passive tobacco smokers schizophrenia patients].
Przeglad lekarski.
2006; 63(10):998-1001. doi:
NULL. [PMID: 17288201] - Toru Sanai, Rei Matsui, Tadashi Hirano, Shinichi Torichigai, Hideki Yotsueda, Harumichi Higashi, Hideki Hirakata, Mitsuo Iida. Successful treatment of six patients with neuroleptic malignant syndrome associated with myoglobulinemic acute renal failure.
Renal failure.
2006; 28(1):51-5. doi:
10.1080/08860220500461252. [PMID: 16526319] - Akemi Marumo, Takeshi Kumazawa, Xiao-Pen Lee, Koichiro Fujimaki, Ayako Kuriki, Chika Hasegawa, Keizo Sato, Hiroshi Seno, Osamu Suzuki. Analysis of phenothiazines in human body fluids using disk solid-phase extraction and liquid chromatography.
Journal of AOAC International.
2005 Nov; 88(6):1655-60. doi:
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Biophysical chemistry.
2005 Sep; 117(2):101-9. doi:
10.1016/j.bpc.2005.05.002. [PMID: 15921844] - Per Skallerup, Luz A Luna, Maria V Johansen, Niels C Kyvsgaard. The impact of natural helminth infections and supplementary protein on growth performance of free-range chickens on smallholder farms in El Sauce, Nicaragua.
Preventive veterinary medicine.
2005 Jul; 69(3-4):229-44. doi:
10.1016/j.prevetmed.2005.02.003. [PMID: 15907572] - Motoe Takayanagi, Naoyo Sano, Hajime Takikawa. Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.
Journal of gastroenterology and hepatology.
2005 May; 20(5):784-8. doi:
10.1111/j.1440-1746.2005.03792.x. [PMID: 15853995] - Shigehiko Takegami, Keisuke Kitamura, Tatsuya Kitade, Miwa Takashima, Mika Ito, Eiko Nakagawa, Midori Sone, Rie Sumitani, Yumiko Yasuda. Effects of phosphatidylserine and phosphatidylethanolamine content on partitioning of triflupromazine and chlorpromazine between phosphatidylcholine-aminophospholipid bilayer vesicles and water studied by second-derivative spectrophotometry.
Chemical & pharmaceutical bulletin.
2005 Jan; 53(1):147-50. doi:
10.1248/cpb.53.147. [PMID: 15635254]