Cyromazine (BioDeep_00000002266)

 

Secondary id: BioDeep_00000404589

human metabolite Endogenous Industrial Pollutants


代谢物信息卡片


2,4-Diamino-6-(cyclopropylamino)-S-triazine (8ci)

化学式: C6H10N6 (166.09669000000002)
中文名称: 环丙氨嗪
谱图信息: 最多检出来源 Homo sapiens(blood) 1.57%

Reviewed

Last reviewed on 2024-08-08.

Cite this Page

Cyromazine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cyromazine (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000002266). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1CC1NC2=NC(=NC(=N2)N)N
InChI: InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)

描述信息

Ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestoc
CONFIDENCE standard compound; INTERNAL_ID 8456
CONFIDENCE standard compound; INTERNAL_ID 3021
CONFIDENCE standard compound; INTERNAL_ID 2625
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
Cyromazine, the cyclopropyl derivative of melamine, is an insect growth regulator used as an insecticide and acaricide that acts by affecting the nervous system in the larval stages of certain insects.

同义名列表

33 个代谢物同义名

2,4-Diamino-6-(cyclopropylamino)-S-triazine (8ci); N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine, 9ci; N(2)-Cyclopropyl-1,3,5-triazine-2,4,6-triamine; N2-Cyclopropyl-1,3,5-triazine-2,4,6-triamine; 2,4-Diamino-6-(cyclopropylamino)-S-triazine; N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine; N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine; N-Cyclopropyl-1,3,5-triazin-2,4,6-triamine; Cyclopropyl-1,3,5-triazine-2,4,6-triamine; 2-Cyclopropylamino-4,6-diamino-S-triazine; Diamino-6-(cyclopropylamino)-S-triazine; N-Cyclopropyltriazine-2,4,6-triamine; Cyromazine dihydrochloride; N-Cyclopropylmelamine; Vetrazin (pesticide); Cyclopropylmelamine; Larvadex premix; Azimethiphos; Cyromazinum; Cypromazine; CYROMAZINE; Ciromazina; Vetrazine; Cyromazin; CGA 72662; Citation; Vetrazin; Larvadex; Trigard; Neoprex; Neporex; Armor; CGA-72662



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shanying Zhang, Yu Zhang, Saihao Ren, Hongwei Lu, Jiaomei Li, Xiaoyu Liang, Lifeng Wang, Yuanbo Li, Meng Wang, Chenghui Zhang. Uptake, translocation and metabolism of acetamiprid and cyromazine by cowpea (Vigna unguiculata L.). Environmental pollution (Barking, Essex : 1987). 2023 May; 331(Pt 1):121839. doi: 10.1016/j.envpol.2023.121839. [PMID: 37201568]
  • Changwei Gong, Ali Hasnain, Qiulin Wang, Dan Liu, Zhengze Xu, Xiaoxu Zhan, Xuemei Liu, Jian Pu, Mengmeng Sun, Xuegui Wang. Eco-friendly deacetylated chitosan base siRNA biological-nanopesticide loading cyromazine for efficiently controlling Spodoptera frugiperda. International journal of biological macromolecules. 2023 Apr; 241(?):124575. doi: 10.1016/j.ijbiomac.2023.124575. [PMID: 37100329]
  • Ya-Wen Chang, Yu-Cheng Wang, Yu-Qing Yan, Cheng-Dong Wu, Hong-Fang Xie, Wei-Rong Gong, Yu-Zhou Du. Insect hormones affect the toxicity of the insecticidal growth regulator cyromazine in Liriomyza trifolii (Diptera: Agromyzidae). Pesticide biochemistry and physiology. 2022 Nov; 188(?):105263. doi: 10.1016/j.pestbp.2022.105263. [PMID: 36464368]
  • Shanying Zhang, Fengman Yin, Jiahao Li, Saihao Ren, Xiaoyu Liang, Yu Zhang, Lifeng Wang, Meng Wang, Chenghui Zhang. Transcriptomic and metabolomic investigation of metabolic disruption in Vigna unguiculata L. triggered by acetamiprid and cyromazine. Ecotoxicology and environmental safety. 2022 Jul; 239(?):113675. doi: 10.1016/j.ecoenv.2022.113675. [PMID: 35617907]
  • Sihua Peng, Aqiang Wang, Yuyang Lian, Jingjing Jia, Xuncong Ji, Heming Yang, Jinlei Li, Shuyan Yang, Jianjun Liao, Shihao Zhou. Technology for Rapid Detection of Cyromazine Residues in Fruits and Vegetables: Molecularly Imprinted Electrochemical Sensors. Biosensors. 2022 Jun; 12(6):. doi: 10.3390/bios12060414. [PMID: 35735561]
  • T Rairat, S C Ou, S K Chang, K P Li, T W Vickroy, C C Chou. Plasma pharmacokinetics and tissue depletion of cyromazine and its metabolite melamine following oral administration in laying chickens. Journal of veterinary pharmacology and therapeutics. 2017 Oct; 40(5):459-467. doi: 10.1111/jvp.12379. [PMID: 27900792]
  • Fangyuan Zhou, Guodong Zhu, Haipeng Zhao, Zheng Wang, Ming Xue, Xianxian Li, Huaqiang Xu, Xiaodan Ma, Yanyan Liu. Sterilization Effects of Adult-targeted Baits Containing Insect Growth Regulators on Delia antiqua. Scientific reports. 2016 09; 6(?):32855. doi: 10.1038/srep32855. [PMID: 27619006]
  • Xian-Hua Wang, Li-Fu Xie, Qian Dong, Hao-Long Liu, Yan-Ping Huang, Zhao-Sheng Liu. Synthesis of monodisperse molecularly imprinted microspheres with multi-recognition ability via precipitation polymerization for the selective extraction of cyromazine, melamine, triamterene and trimethoprim. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Dec; 1007(?):127-31. doi: 10.1016/j.jchromb.2015.11.009. [PMID: 26595796]
  • Qing-Bo Wei, Zhong-Ren Lei, Ralf Nauen, Du-Cheng Cai, Yu-Lin Gao. Abamectin resistance in strains of vegetable leafminer, Liriomyza sativae (Diptera: Agromyzidae) is linked to elevated glutathione S-transferase activity. Insect science. 2015 Apr; 22(2):243-50. doi: 10.1111/1744-7917.12080. [PMID: 25813391]
  • Mihaela Kavran, Marija F Zgomba, Aleksandra M Ignjatovic-Ćupina, Sanja D Lazić, Dušan V Petrić. Choice of optimal biocide combination to control flies (Diptera: Muscidae). Annals of agricultural and environmental medicine : AAEM. 2015; 22(2):243-6. doi: 10.5604/12321966.1152073. [PMID: 26094516]
  • Xusheng Ge, Xingqiang Wu, Shuxuan Liang, Hanwen Sun. A sensitive and validated HPLC method for the determination of cyromazine and melamine in herbal and edible plants using accelerated solvent extraction and cleanup with SPE. Journal of chromatographic science. 2014 Aug; 52(7):751-7. doi: 10.1093/chromsci/bmt089. [PMID: 23845887]
  • D B Taylor, K Friesen, J J Zhu, K Sievert. Efficacy of cyromazine to control immature stable flies (Diptera: Muscidae) developing in winter hay feeding sites. Journal of economic entomology. 2012 Apr; 105(2):726-31. doi: 10.1603/ec11317. [PMID: 22606846]
  • Yulin Gao, Stuart R Reitz, Qingbo Wei, Wenyan Yu, Zhongren Lei. Insecticide-mediated apparent displacement between two invasive species of leafminer fly. PloS one. 2012; 7(5):e36622. doi: 10.1371/journal.pone.0036622. [PMID: 22662122]
  • Marianna Marangi, Vincenzo Morelli, Sandra Pati, Antonio Camarda, Maria Assunta Cafiero, Annunziata Giangaspero. Acaricide residues in laying hens naturally infested by red mite Dermanyssus gallinae. PloS one. 2012; 7(2):e31795. doi: 10.1371/journal.pone.0031795. [PMID: 22363736]
  • Yulin Gao, Zhongren Lei, Yoshihisa Abe, Stuart R Reitz. Species displacements are common to two invasive species of leafminer fly in China, Japan, and the United States. Journal of economic entomology. 2011 Dec; 104(6):1771-3. doi: 10.1603/ec11206. [PMID: 22299335]
  • Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. Journal of medicinal chemistry. 2011 Jul; 54(13):4548-58. doi: 10.1021/jm2001629. [PMID: 21599003]
  • Terence L Fodey, Colin S Thompson, Imelda M Traynor, Simon A Haughey, D Glenn Kennedy, Steven R H Crooks. Development of an optical biosensor based immunoassay to screen infant formula milk samples for adulteration with melamine. Analytical chemistry. 2011 Jun; 83(12):5012-6. doi: 10.1021/ac200926e. [PMID: 21557539]
  • Qiang Wang, Simon A Haughey, Yuan-Ming Sun, Sergei A Eremin, Zhen-Feng Li, Hui Liu, Zhen-Lin Xu, Yu-Dong Shen, Hong-Tao Lei. Development of a fluorescence polarization immunoassay for the detection of melamine in milk and milk powder. Analytical and bioanalytical chemistry. 2011 Feb; 399(6):2275-84. doi: 10.1007/s00216-010-4599-2. [PMID: 21221551]
  • Ricardo Hernández, Marvin Harris, Tong-Xian Liu. Impact of insecticides on parasitoids of the leafminer, Liriomyza trifolii, in pepper in south Texas. Journal of insect science (Online). 2011; 11(?):61. doi: 10.1673/031.011.6101. [PMID: 21864155]
  • Le-Le Hu, Chen Chen, Tao Huang, Yu-Dong Cai, Kuo-Chen Chou. Predicting biological functions of compounds based on chemical-chemical interactions. PloS one. 2011; 6(12):e29491. doi: 10.1371/journal.pone.0029491. [PMID: 22220213]
  • Hongtao Lei, Yudong Shen, Lijun Song, Jinyi Yang, Olivier P Chevallier, Simon A Haughey, Hong Wang, Yuanming Sun, Christopher T Elliott. Hapten synthesis and antibody production for the development of a melamine immunoassay. Analytica chimica acta. 2010 Apr; 665(1):84-90. doi: 10.1016/j.aca.2010.03.007. [PMID: 20381695]
  • L A Mwamburi, M D Laing, R Miller. Interaction between Beauveria bassiana and Bacillus thuringiensis var. israelensis for the control of house fly larvae and adults in poultry houses. Poultry science. 2009 Nov; 88(11):2307-14. doi: 10.3382/ps.2009-00212. [PMID: 19834080]
  • George Patakioutas, Dimitrios Savvas, Christos Matakoulis, Theofanis Sakellarides, Triantafyllos Albanis. Application and fate of Cyromazine in a closed-cycle hydroponic cultivation of bean (Phaseolus vulgaris L.). Journal of agricultural and food chemistry. 2007 Nov; 55(24):9928-35. doi: 10.1021/jf071726i. [PMID: 17979234]
  • R Karimzadeh, M J Hejazi, F Rahimzadeh Khoei, M Moghaddam. Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata. Journal of insect science (Online). 2007; 7(?):1-6. doi: 10.1673/031.007.5001. [PMID: 20345285]
  • H S Civelek, P G Weintraub. Effects of two plant extracts on larval leafminer Liriomyza trifolii (Diptera: Agromyzidae) in tomatoes. Journal of economic entomology. 2004 Oct; 97(5):1581-6. doi: 10.1603/0022-0493-97.5.1581. [PMID: 15568346]
  • Djoko Prijono, Michelle Robinson, Aunu Rauf, Tracey Bjorksten, Ary A Hoffmann. Toxicity of chemicals commonly used in Indonesian vegetable crops to Liriomyza huidobrensis populations and the Indonesian parasitoids Hemiptarsenus varicornis, Opius sp., and Gronotoma micromorpha, as well as the Australian parasitoids Hemiptarsenus varicornis and Diglyphus isaea. Journal of economic entomology. 2004 Aug; 97(4):1191-7. doi: 10.1093/jee/97.4.1191. [PMID: 15384326]
  • D A Ostlind, A S Misura, T Tamas, D R Andersen, T Felcetto, S K Smith, W G Mickle. Determination of poultry feed-through insecticide activity in an in vivo anticoccidial assay. The Journal of parasitology. 2004 Apr; 90(2):421-2. doi: 10.1645/ge-3270rn. [PMID: 15165074]
  • Juliet D Tang, Michael A Caprio, D Craig Sheppard, Douglas M Gaydon. Genetics and fitness costs of cyromazine resistance in the house fly (Diptera: Muscidae). Journal of economic entomology. 2002 Dec; 95(6):1251-60. doi: 10.1603/0022-0493-95.6.1251. [PMID: 12539839]
  • A A Jukes, R H Collier, S Finch. Cabbage root fly control using non-organophosphorus insecticides. Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen). 2001; 66(2a):395-402. doi: ". [PMID: 12425060]
  • Y Braverman, A Chizov-Ginzburg, I Yeruham, O Kolsky, A Saran. Control experiments with yellow jacket wasps (Hymenoptera: Vespidae) injuring cattle in Israel. Journal of economic entomology. 1998 Apr; 91(2):486-91. doi: 10.1093/jee/91.2.486. [PMID: 9589629]
  • R W Miller, E T Schmidtmann, R D Wauchope, C M Clegg, A E Herner, H Weber. Urine delivery of cyromazine for suppressing house and stable flies (diptera: muscidae) in outdoor dairy calf hutches. Journal of economic entomology. 1996 Jun; 89(3):689-94. doi: 10.1093/jee/89.3.689. [PMID: 8642111]
  • A M Mostafa, Y M Ahmed, M T Ahmed. Feeding cyromazine to Luhmann hens: residues in tissues and effects on some biochemical constituents. Journal of the Egyptian Society of Parasitology. 1994 Aug; 24(2):259-69. doi: . [PMID: 8077746]
  • M T Ahmed, Y M Ahmed, A M Mostafa. Feeding cyromazine to Luhmann hens: residues in tissues and effects on some biochemical constituents. Die Nahrung. 1992; 36(1):84-6. doi: 10.1002/food.19920360112. [PMID: 1579155]
  • J Brake, R C Axtell, W R Campbell. Retention of larvicidal activity after feeding cyromazine (Larvadex) for the initial 20 weeks of life of single comb White Leghorn layers. Poultry science. 1991 Sep; 70(9):1873-5. doi: 10.3382/ps.0701873. [PMID: 1780256]
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