Natsudaidain (BioDeep_00000021588)

 

Secondary id: BioDeep_00000270304

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


2-(3,4-Dimethoxyphenyl)-3-hydroxy-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one

化学式: C21H22O9 (418.1263762)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 37.5%

分子结构信息

SMILES: c1(c(c(c2c(c1OC)oc(c(c2=O)O)c1ccc(c(c1)OC)OC)OC)OC)OC
InChI: InChI=1S/C21H22O9/c1-24-11-8-7-10(9-12(11)25-2)16-15(23)14(22)13-17(26-3)19(27-4)21(29-6)20(28-5)18(13)30-16/h7-9,23H,1-6H3

描述信息

Natsudaidain is a polyphenol compound found in foods of plant origin (PMID: 20428313)

同义名列表

7 个代谢物同义名

2-(3,4-Dimethoxyphenyl)-3-hydroxy-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one; 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,6,7,8-tetramethoxy-4H-chromen-4-one; 3-Hydroxy-3,4,5,6,7,8-hexamethoxyflavone; 3-Hydroxy-5,6,7,8,3,4-hexamethoxyflavone; 3,4,5,6,7,8-Hexamethoxyflavonol; 3-Hydroxynobiletin; Natsudaidain



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mathusalini Sadasivam, Chandraprakash Kumarasamy, Arasakumar Thangaraj, Mani Govindan, Gayathri Kasirajan, Viswanathan Vijayan, Velmurugan Devadasan, Lin Chia-Her, Gogul Ramnath Madhusudhanan, Thirugnanasampandan Ramaraj, Mohan Palathurai Subramaniam. Phytochemical constituents from dietary plant Citrus hystrix. Natural product research. 2018 Jul; 32(14):1721-1726. doi: 10.1080/14786419.2017.1399386. [PMID: 29117732]
  • Takuya Matsui, Chihiro Ito, Masataka Itoigawa, Tadashi Okada, Hiroshi Furukawa. Effect of natsudaidain isolated from Citrus plants on TNF-alpha and cyclooxygenase-2 expression in RBL-2H3 cells. The Journal of pharmacy and pharmacology. 2009 Jan; 61(1):109-14. doi: 10.1211/jpp/61.01.0015. [PMID: 19126304]
  • Yoshiki Miyata, Takashi Sato, Keisuke Imada, Akira Dobashi, Masamichi Yano, Akira Ito. A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells. Biochemical and biophysical research communications. 2008 Feb; 366(1):168-73. doi: 10.1016/j.bbrc.2007.11.100. [PMID: 18053806]
  • Shiming Li, Min-Hsiung Pan, Ching-Shu Lai, Chih-Yu Lo, Slavik Dushenkov, Chi-Tang Ho. Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines. Bioorganic & medicinal chemistry. 2007 May; 15(10):3381-9. doi: 10.1016/j.bmc.2007.03.021. [PMID: 17391969]
  • S Kawaii, Y Tomono, E Katase, K Ogawa, M Nonomura-Nakano, H Nesumi, T Yoshida, M Sugiura, M Yano. Quantitative study of fruit flavonoids in citrus hybrids of King (C. nobilis) and Mukaku Kishu (C. kinokuni). Journal of agricultural and food chemistry. 2001 Aug; 49(8):3982-6. doi: 10.1021/jf0100292. [PMID: 11513699]
  • S Qian, L Chen. [Studies on the chemical constituents of Citrus reticulata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 1998 Jun; 21(6):301-2. doi: ". [PMID: 12567525]
  • M Itoigawa, K Takeya, H Furukawa. Cardiotonic flavonoids from Citrus plants (Rutaceae). Biological & pharmaceutical bulletin. 1994 Nov; 17(11):1519-21. doi: 10.1248/bpb.17.1519. [PMID: 7703977]