PIP(22:5(4Z,7Z,10Z,13Z,16Z)/PGD2) (BioDeep_00000205617)

   

human metabolite


代谢物信息卡片


{[(1S,6R,12Z,15S,16S,19R,20R,21R,22R,23S,24R)-6-{[(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoyloxy]methyl}-3,16,20,22,23,24-hexahydroxy-19-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,8,18-trioxo-2,4,7-trioxa-3lambda5-phosphabicyclo[13.6.3]tetracos-12-en-21-yl]oxy}phosphonic acid

化学式: C51H82O19P2 (1060.4925282)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(=O)OC[C@@H]1COP(O)(=O)O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C\C=C/CCCC(=O)O1)[C@@H](O)CC(=O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@H](O)[C@H]2OP(O)(O)=O
InChI: InChI=1S/C51H82O19P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-27-31-44(55)66-36-39-37-67-72(64,65)70-51-49(60)48(59)46(57)40(30-26-23-24-28-32-45(56)68-39)42(53)35-43(54)41(34-33-38(52)29-25-6-4-2)47(58)50(51)69-71(61,62)63/h9-10,12-13,15-16,18-19,21-23,26,33-34,38-42,46-53,57-60H,3-8,11,14,17,20,24-25,27-32,35-37H2,1-2H3,(H,64,65)(H2,61,62,63)/b10-9-,13-12-,16-15-,19-18-,22-21-,26-23-,34-33+/t38-,39+,40-,41-,42-,46+,47+,48-,49+,50+,51-/m0/s1

描述信息

PIP(22:5(4Z,7Z,10Z,13Z,16Z)/PGD2) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(22:5(4Z,7Z,10Z,13Z,16Z)/PGD2), in particular, consists of one chain of 4Z,7Z,10Z,13Z,16Z-docosapentaenoyl at the C-1 position and one chain of Prostaglandin D2 at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,12Z,15S,16S,19R,20R,21R,22R,23S,24R)-6-{[(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoyloxy]methyl}-3,16,20,22,23,24-hexahydroxy-19-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,8,18-trioxo-2,4,7-trioxa-3lambda5-phosphabicyclo[13.6.3]tetracos-12-en-21-yl]oxy}phosphonic acid; [(1S,6R,12Z,15S,16S,19R,20R,21R,22R,23S,24R)-6-{[(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoyloxy]methyl}-3,16,20,22,23,24-hexahydroxy-19-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,8,18-trioxo-2,4,7-trioxa-3lambda5-phosphabicyclo[13.6.3]tetracos-12-en-21-yl]oxyphosphonic acid; {[(1S,6R,12Z,15S,16S,19R,20R,21R,22R,23S,24R)-6-{[(7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoyloxy]methyl}-3,16,20,22,23,24-hexahydroxy-19-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,8,18-trioxo-2,4,7-trioxa-3-phosphabicyclo[13.6.3]tetracos-12-en-21-yl]oxy}phosphonate; PIP(22:5(4Z,7Z,10Z,13Z,16Z)/PGD2)



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