PIP(PGE1/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000205580)

   

human metabolite


代谢物信息卡片


{[(1S,6R,16R,19R,20S,21R,22R,23R,24S,25R)-6-[(7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyloxy]-3,19,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,17-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonic acid

化学式: C51H86O19P2 (1064.5238266)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(=O)O[C@@H]1COC(=O)CCCCCC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](OP(O)(=O)OC1)[C@H](OP(O)(O)=O)[C@H](O)[C@@H](\C=C\[C@@H](O)CCCCC)[C@H](O)CC2=O
InChI: InChI=1S/C51H86O19P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-28-32-45(56)68-39-36-66-44(55)31-27-24-23-26-30-40-42(53)35-43(54)41(34-33-38(52)29-25-6-4-2)47(58)50(69-71(61,62)63)51(49(60)48(59)46(40)57)70-72(64,65)67-37-39/h9-10,12-13,15-16,18-19,33-34,38-41,43,46-52,54,57-60H,3-8,11,14,17,20-32,35-37H2,1-2H3,(H,64,65)(H2,61,62,63)/b10-9-,13-12-,16-15-,19-18-,34-33+/t38-,39+,40-,41-,43+,46+,47+,48-,49+,50+,51-/m0/s1

描述信息

PIP(PGE1/22:4(7Z,10Z,13Z,16Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(PGE1/22:4(7Z,10Z,13Z,16Z)), in particular, consists of one chain of Prostaglandin E1 at the C-1 position and one chain of 7Z,10Z,13Z,16Z-docosatetraenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,16R,19R,20S,21R,22R,23R,24S,25R)-6-[(7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyloxy]-3,19,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,17-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonic acid; [(1S,6R,16R,19R,20S,21R,22R,23R,24S,25R)-6-[(7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyloxy]-3,19,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,17-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxyphosphonic acid; {[(1S,6R,16R,19R,20S,21R,22R,23R,24S,25R)-6-[(7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyloxy]-3,19,21,23,24,25-hexahydroxy-20-[(3S)-3-hydroxyoct-1-en-1-yl]-3,9,17-trioxo-2,4,8-trioxa-3-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonate; PIP(PGE1/22:4(7Z,10Z,13Z,16Z))



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1 个相关的物种来源信息

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