Hexadecenoylcarnitine(Car 16:1) (BioDeep_00002055734)

描述信息

Hexadecenoylcarnitine (Car 16:1) is a naturally occurring derivative of carnitine, which plays a crucial role in the transport of long-chain fatty acids across the mitochondrial membrane for beta-oxidation. This process is essential for the production of energy in the body.

The name “Hexadecenoylcarnitine” refers to its structure: it consists of a 16-carbon fatty acid chain with one double bond (hence the “16:1” notation), esterified to carnitine. The presence of the double bond at a specific position in the fatty acid chain imparts unique properties to this molecule.

In biological systems, Hexadecenoylcarnitine is involved in several important functions:

Energy Metabolism: It facilitates the transport of fatty acids into the mitochondria, where they undergo beta-oxidation to produce ATP, the cell’s primary energy source.
Regulation of Fatty Acid Oxidation: It helps regulate the rate of fatty acid oxidation, which is particularly important in tissues with high energy demands, such as the heart and skeletal muscles.
Homeostasis: Hexadecenoylcarnitine is involved in maintaining the balance of fatty acids and their CoA esters across the mitochondrial membrane.
Potential Biomarker: Levels of Hexadecenoylcarnitine in the blood can serve as a biomarker for certain metabolic disorders and may indicate abnormalities in fatty acid metabolism.
Research Interest: It is of interest in research for its potential roles in various diseases, including cardiovascular diseases and metabolic disorders.
Hexadecenoylcarnitine is synthesized in the body and can also be obtained from dietary sources, particularly those rich in unsaturated fatty acids. Its metabolism is tightly regulated by various enzymes and transporters, ensuring efficient energy production and maintaining cellular homeostasis.

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