PIP(5-iso PGF2VI/20:4(8Z,11Z,14Z,17Z)) (BioDeep_00000205117)

   

human metabolite


代谢物信息卡片


{[(1S,6R,11Z,14R,15S,17R,18S,19R,20R,21R,22S,23R)-3,15,17,19,21,22,23-heptahydroxy-18-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-6-[(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyloxy]-3,9-dioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[12.6.3]tricos-11-en-20-yl]oxy}phosphonic acid

化学式: C47H78O19P2 (1008.4612298000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@H]2C\C=C/CC(=O)OC[C@H](COP(O)(=O)O[C@@H]([C@H](O)[C@@H](O)[C@@H]2O)[C@H](OP(O)(O)=O)[C@@H]1O)OC(=O)CCCCCC\C=C/C\C=C/C\C=C/C\C=C/CC
InChI: InChI=1S/C47H78O19P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-28-41(52)64-35-32-62-40(51)27-24-23-26-36-38(49)31-39(50)37(30-29-34(48)25-21-6-4-2)43(54)46(65-67(57,58)59)47(45(56)44(55)42(36)53)66-68(60,61)63-33-35/h5,7,9-10,12-13,15-16,23-24,29-30,34-39,42-50,53-56H,3-4,6,8,11,14,17-22,25-28,31-33H2,1-2H3,(H,60,61)(H2,57,58,59)/b7-5-,10-9-,13-12-,16-15-,24-23-,30-29+/t34-,35-,36-,37+,38+,39-,42-,43-,44+,45-,46-,47+/m1/s1

描述信息

PIP(5-iso PGF2VI/20:4(8Z,11Z,14Z,17Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(5-iso PGF2VI/20:4(8Z,11Z,14Z,17Z)), in particular, consists of one chain of 5-iso Prostaglandin F2alpha-VI at the C-1 position and one chain of 8Z,11Z,14Z,17Z-eicosapentaenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,11Z,14R,15S,17R,18S,19R,20R,21R,22S,23R)-3,15,17,19,21,22,23-heptahydroxy-18-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-6-[(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyloxy]-3,9-dioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[12.6.3]tricos-11-en-20-yl]oxy}phosphonic acid; [(1S,6R,11Z,14R,15S,17R,18S,19R,20R,21R,22S,23R)-3,15,17,19,21,22,23-heptahydroxy-18-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-6-[(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyloxy]-3,9-dioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[12.6.3]tricos-11-en-20-yl]oxyphosphonic acid; {[(1S,6R,11Z,14R,15S,17R,18S,19R,20R,21R,22S,23R)-3,15,17,19,21,22,23-heptahydroxy-18-[(3R)-3-hydroxyoct-1-en-1-yl]-6-[(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyloxy]-3,9-dioxo-2,4,8-trioxa-3-phosphabicyclo[12.6.3]tricos-11-en-20-yl]oxy}phosphonate; PIP(5-iso PGF2VI/20:4(8Z,11Z,14Z,17Z))



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