PIP(PGD2/20:1(11Z)) (BioDeep_00000204579)

   

human metabolite


代谢物信息卡片


{[(1S,6R,13Z,16S,17S,20R,21R,22R,23R,24S,25R)-3,17,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-icos-11-enoyloxy]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacos-13-en-22-yl]oxy}phosphonic acid

化学式: C49H86O19P2 (1040.5238266)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCC\C=C/CCCCCCCCCC(=O)O[C@@H]1COC(=O)CCC\C=C/C[C@H]2[C@@H](O)CC(=O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H](OP(O)(=O)OC1)[C@H](O)[C@@H](O)[C@@H]2O
InChI: InChI=1S/C49H86O19P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-30-43(54)66-37-34-64-42(53)29-25-22-21-24-28-38-40(51)33-41(52)39(32-31-36(50)27-23-6-4-2)45(56)48(67-69(59,60)61)49(47(58)46(57)44(38)55)68-70(62,63)65-35-37/h12-13,21,24,31-32,36-40,44-51,55-58H,3-11,14-20,22-23,25-30,33-35H2,1-2H3,(H,62,63)(H2,59,60,61)/b13-12-,24-21-,32-31+/t36-,37+,38-,39-,40-,44+,45+,46-,47+,48+,49-/m0/s1

描述信息

PIP(PGD2/20:1(11Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(PGD2/20:1(11Z)), in particular, consists of one chain of Prostaglandin D2 at the C-1 position and one chain of 11Z-eicosenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,13Z,16S,17S,20R,21R,22R,23R,24S,25R)-3,17,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-icos-11-enoyloxy]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacos-13-en-22-yl]oxy}phosphonic acid; [(1S,6R,13Z,16S,17S,20R,21R,22R,23R,24S,25R)-3,17,21,23,24,25-hexahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-icos-11-enoyloxy]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacos-13-en-22-yl]oxyphosphonic acid; {[(1S,6R,13Z,16S,17S,20R,21R,22R,23R,24S,25R)-3,17,21,23,24,25-hexahydroxy-20-[(3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-icos-11-enoyloxy]-3,9,19-trioxo-2,4,8-trioxa-3-phosphabicyclo[14.6.3]pentacos-13-en-22-yl]oxy}phosphonate; PIP(PGD2/20:1(11Z))



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代谢反应

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1 个相关的物种来源信息

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