PIP(TXB2/18:2(9Z,12Z)) (BioDeep_00000204176)

   

human metabolite


代谢物信息卡片


{[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonic acid

化学式: C47H82O20P2 (1028.4874432)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC\C=C/C\C=C/CCCCCCCC(=O)O[C@@H]1COC(=O)CCC\C=C/C[C@H]2[C@@H](O)CC(O)O[C@H](\C=C\[C@@H](O)CCCCC)[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H](OP(O)(=O)OC1)[C@H](O)[C@@H](O)[C@@H]2O
InChI: InChI=1S/C47H82O20P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-24-28-40(51)64-35-32-62-39(50)27-23-20-19-22-26-36-37(49)31-41(52)65-38(30-29-34(48)25-21-6-4-2)43(54)46(66-68(57,58)59)47(45(56)44(55)42(36)53)67-69(60,61)63-33-35/h9-10,12-13,19,22,29-30,34-38,41-49,52-56H,3-8,11,14-18,20-21,23-28,31-33H2,1-2H3,(H,60,61)(H2,57,58,59)/b10-9-,13-12-,22-19-,30-29+/t34-,35+,36-,37-,38+,41?,42+,43+,44-,45+,46+,47-/m0/s1

描述信息

PIP(TXB2/18:2(9Z,12Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(TXB2/18:2(9Z,12Z)), in particular, consists of one chain of Thromboxane B2 at the C-1 position and one chain of 9Z,12Z-octadecadienoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonic acid; [(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxyphosphonic acid; {[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3,9-dioxo-2,4,8,20-tetraoxa-3-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonate; PIP(TXB2/18:2(9Z,12Z))



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1 个相关的物种来源信息

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