PIP(18:3(10,12,15)-OH(9)/18:1(9Z)) (BioDeep_00000204122)

   

human metabolite


代谢物信息卡片


{[(1R,5S)-2,3,4,6-tetrahydroxy-5-({hydroxy[(2R)-3-{[(10E,12E,15E)-9-hydroxyoctadeca-10,12,15-trienoyl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphoryl}oxy)cyclohexyl]oxy}phosphonic acid

化学式: C45H80O17P2 (954.4870490000002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: [H][C@@](COC(=O)CCCCCCCC(O)\C=C\C=C\C\C=C\CC)(COP(O)(=O)O[C@H]1C(O)C(O)C(O)[C@@H](OP(O)(O)=O)C1O)OC(=O)CCCCCCC\C=C/CCCCCCCC
InChI: InChI=1S/C45H80O17P2/c1-3-5-7-9-11-12-13-14-15-16-17-18-20-24-29-33-39(48)60-37(34-58-38(47)32-28-25-21-23-27-31-36(46)30-26-22-19-10-8-6-4-2)35-59-64(56,57)62-45-42(51)40(49)41(50)44(43(45)52)61-63(53,54)55/h6,8,14-15,19,22,26,30,36-37,40-46,49-52H,3-5,7,9-13,16-18,20-21,23-25,27-29,31-35H2,1-2H3,(H,56,57)(H2,53,54,55)/b8-6+,15-14-,22-19+,30-26+/t36?,37-,40?,41?,42?,43?,44-,45+/m1/s1

描述信息

PIP(18:3(10,12,15)-OH(9)/18:1(9Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(18:3(10,12,15)-OH(9)/18:1(9Z)), in particular, consists of one chain of 9-hydroxyoctadecatrienoyl at the C-1 position and one chain of 9Z-octadecenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1R,5S)-2,3,4,6-tetrahydroxy-5-({hydroxy[(2R)-3-{[(10E,12E,15E)-9-hydroxyoctadeca-10,12,15-trienoyl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphoryl}oxy)cyclohexyl]oxy}phosphonic acid; [(1R,5S)-2,3,4,6-tetrahydroxy-5-{[hydroxy((2R)-3-{[(10E,12E,15E)-9-hydroxyoctadeca-10,12,15-trienoyl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propoxy)phosphoryl]oxy}cyclohexyl]oxyphosphonic acid; {[(1R,5S)-2,3,4,6-tetrahydroxy-5-({hydroxy[(2R)-3-{[(10E,12E,15E)-9-hydroxyoctadeca-10,12,15-trienoyl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphoryl}oxy)cyclohexyl]oxy}phosphonate; PIP(18:3(10,12,15)-OH(9)/18:1(9Z))



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