PIP(6 keto-PGF1alpha/18:1(11Z)) (BioDeep_00000203855)

   

human metabolite


代谢物信息卡片


{[(1S,6R,16S,17S,19R,20S,21R,22R,23R,24S,25R)-3,17,19,21,23,24,25-heptahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-octadec-11-enoyloxy]-3,9,14-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonic acid

化学式: C47H84O20P2 (1030.5030924)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC\C=C/CCCCCCCCCC(=O)O[C@@H]1COC(=O)CCCCC(=O)C[C@H]2[C@@H](O)C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H](OP(O)(=O)OC1)[C@H](O)[C@@H](O)[C@@H]2O
InChI: InChI=1S/C47H84O20P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-20-26-41(53)65-35-31-63-40(52)25-22-21-24-34(49)29-37-39(51)30-38(50)36(28-27-33(48)23-19-6-4-2)43(55)46(66-68(58,59)60)47(45(57)44(56)42(37)54)67-69(61,62)64-32-35/h10-11,27-28,33,35-39,42-48,50-51,54-57H,3-9,12-26,29-32H2,1-2H3,(H,61,62)(H2,58,59,60)/b11-10-,28-27+/t33-,35+,36-,37-,38+,39-,42+,43+,44-,45+,46+,47-/m0/s1

描述信息

PIP(6 keto-PGF1alpha/18:1(11Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(6 keto-PGF1alpha/18:1(11Z)), in particular, consists of one chain of 6-Keto-prostaglandin F1alpha at the C-1 position and one chain of 11Z-octadecenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,16S,17S,19R,20S,21R,22R,23R,24S,25R)-3,17,19,21,23,24,25-heptahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-octadec-11-enoyloxy]-3,9,14-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonic acid; [(1S,6R,16S,17S,19R,20S,21R,22R,23R,24S,25R)-3,17,19,21,23,24,25-heptahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-octadec-11-enoyloxy]-3,9,14-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosan-22-yl]oxyphosphonic acid; {[(1S,6R,16S,17S,19R,20S,21R,22R,23R,24S,25R)-3,17,19,21,23,24,25-heptahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-[(11Z)-octadec-11-enoyloxy]-3,9,14-trioxo-2,4,8-trioxa-3-phosphabicyclo[14.6.3]pentacosan-22-yl]oxy}phosphonate; PIP(6 keto-PGF1alpha/18:1(11Z))



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1 个相关的物种来源信息

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