PIP(TXB2/16:2(9Z,12Z)) (BioDeep_00000203658)

   

human metabolite


代谢物信息卡片


{[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-6-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonic acid

化学式: C45H78O20P2 (1000.4561448000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]2C\C=C/CCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]([C@H](O)[C@@H](O)[C@@H]2O)[C@H](OP(O)(O)=O)[C@@H]1O)OC(=O)CCCCCCC\C=C/C\C=C/CCC
InChI: InChI=1S/C45H78O20P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-22-26-38(49)62-33-30-60-37(48)25-21-18-17-20-24-34-35(47)29-39(50)63-36(28-27-32(46)23-19-6-4-2)41(52)44(64-66(55,56)57)45(43(54)42(53)40(34)51)65-67(58,59)61-31-33/h7-8,10-11,17,20,27-28,32-36,39-47,50-54H,3-6,9,12-16,18-19,21-26,29-31H2,1-2H3,(H,58,59)(H2,55,56,57)/b8-7-,11-10-,20-17-,28-27+/t32-,33+,34-,35-,36+,39?,40+,41+,42-,43+,44+,45-/m0/s1

描述信息

PIP(TXB2/16:2(9Z,12Z)) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(TXB2/16:2(9Z,12Z)), in particular, consists of one chain of Thromboxane B2 at the C-1 position and one chain of 9Z,12Z-hexadecenoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-6-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonic acid; [(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-6-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9-dioxo-2,4,8,20-tetraoxa-3lambda5-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxyphosphonic acid; {[(1S,6R,13Z,16S,17S,21R,22R,23R,24R,25S,26R)-6-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3,17,19,22,24,25,26-heptahydroxy-21-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9-dioxo-2,4,8,20-tetraoxa-3-phosphabicyclo[14.7.3]hexacos-13-en-23-yl]oxy}phosphonate; PIP(TXB2/16:2(9Z,12Z))



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1 个相关的物种来源信息

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