PIP(PGJ2/16:0) (BioDeep_00000203444)

   

human metabolite


代谢物信息卡片


{[(1S,6R,13Z,16S,20R,21R,22R,23R,24S,25R)-6-(hexadecanoyloxy)-3,21,23,24,25-pentahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosa-13,17-dien-22-yl]oxy}phosphonic acid

化学式: C45H78O18P2 (968.4663148000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(=O)O[C@@H]1COC(=O)CCC\C=C/C[C@H]2C=CC(=O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H](OP(O)(=O)OC1)[C@H](O)[C@@H](O)[C@@H]2O
InChI: InChI=1S/C45H78O18P2/c1-3-5-7-8-9-10-11-12-13-14-15-16-22-26-39(49)61-35-31-59-38(48)25-21-18-17-20-23-33-27-30-37(47)36(29-28-34(46)24-19-6-4-2)41(51)44(62-64(54,55)56)45(43(53)42(52)40(33)50)63-65(57,58)60-32-35/h17,20,27-30,33-36,40-46,50-53H,3-16,18-19,21-26,31-32H2,1-2H3,(H,57,58)(H2,54,55,56)/b20-17-,29-28+,30-27?/t33-,34-,35+,36-,40+,41+,42?,43+,44+,45-/m0/s1

描述信息

PIP(PGJ2/16:0) is an oxidized phosphatidylinositol phosphate (PIP). As other PIPs, oxidized phosphatidylinositol phosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a phosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol phosphates are generated from phosphatidylinositols, which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositol phosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PIP(PGJ2/16:0), in particular, consists of one chain of Prostaglandin J2 at the C-1 position and one chain of hexadecanoyl at the C-2 position. The most important phosphatidylinositol phosphate in both quantitative and biological terms is phosphatidylinositol 4-phosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositol phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.

同义名列表

4 个代谢物同义名

{[(1S,6R,13Z,16S,20R,21R,22R,23R,24S,25R)-6-(hexadecanoyloxy)-3,21,23,24,25-pentahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosa-13,17-dien-22-yl]oxy}phosphonic acid; [(1S,6R,13Z,16S,20R,21R,22R,23R,24S,25R)-6-(hexadecanoyloxy)-3,21,23,24,25-pentahydroxy-20-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3,9,19-trioxo-2,4,8-trioxa-3lambda5-phosphabicyclo[14.6.3]pentacosa-13,17-dien-22-yl]oxyphosphonic acid; {[(1S,6R,13Z,16S,20R,21R,22R,23R,25R)-6-(hexadecanoyloxy)-3,21,23,24,25-pentahydroxy-20-[(3S)-3-hydroxyoct-1-en-1-yl]-3,9,19-trioxo-2,4,8-trioxa-3-phosphabicyclo[14.6.3]pentacosa-13,17-dien-22-yl]oxy}phosphonate; PIP(PGJ2/16:0)



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