Valylvaline (BioDeep_00000019160)

   

human metabolite Endogenous


代谢物信息卡片


(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-methylbutanoic acid

化学式: C10H20N2O3 (216.1474)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(feces) 92.62%

分子结构信息

SMILES: CC(C)C(C(=O)NC(C(C)C)C(=O)O)N
InChI: InChI=1S/C10H20N2O3/c1-5(2)7(11)9(13)12-8(6(3)4)10(14)15/h5-8H,11H2,1-4H3,(H,12,13)(H,14,15)

描述信息

Valylvaline is a dipeptide composed of two valine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
H-VAL-VAL-OH is a dipeptide of the amino acid valine, an essential amino acid[1].

同义名列表

16 个代谢物同义名

(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-methylbutanoic acid; Valine-valine dipeptide; Valine valine dipeptide; N-L-Valyl-L-valine; H-L-Val-L-val-OH; L-Valyl-L-valine; V-V Dipeptide; N-Valylvaline; H-Val-val-OH; Valyl-valine; VV Dipeptide; Valylvaline; L-Val-L-val; Di-valine; Val-val; V-V



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • E Ashrafi, A Alemzadeh, M Ebrahimi, E Ebrahimie, N Dadkhodaei, M Ebrahimi. Amino Acid Features of P1B-ATPase Heavy Metal Transporters Enabling Small Numbers of Organisms to Cope with Heavy Metal Pollution. Bioinformatics and biology insights. 2011 Apr; 5(?):59-82. doi: 10.4137/bbi.s6206. [PMID: 21573033]
  • Evropi Papadopoulou, Gregory Tripsianis, Konstantinos Anagnostopoulos, Ioannis Tentes, Stylianos Kakolyris, Georgios Galazios, Efthimios Sivridis, Konstantinos Simopoulos, Alexandros Kortsaris. Significance of serum tumor necrosis factor-alpha and its combination with HER-2 codon 655 polymorphism in the diagnosis and prognosis of breast cancer. The International journal of biological markers. 2010 Jul; 25(3):126-35. doi: 10.1177/172460081002500302. [PMID: 20872355]
  • Tsai-Nung Kuo Chou, Ying-Shiuan Li, Ko-Huang Lue, Che-Feng Liao, Chien-Yu Lin, Pei-Rung Tzeng, Ruey-Hong Wong. Genetic polymorphism of manganese superoxide dismutase is associated with childhood asthma. The Journal of asthma : official journal of the Association for the Care of Asthma. 2010 Jun; 47(5):532-8. doi: 10.3109/02770901003686472. [PMID: 20536280]
  • Griet Van Zeebroeck, Beatriz Monge Bonini, Matthias Versele, Johan M Thevelein. Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nature chemical biology. 2009 Jan; 5(1):45-52. doi: 10.1038/nchembio.132. [PMID: 19060912]
  • Hui Yu, Zhijun Zhang, Yongmei Shi, Feng Bai, Chunming Xie, Yun Qian, Yonggui Yuan, Linglong Deng. Association study of the decreased serum BDNF concentrations in amnestic mild cognitive impairment and the Val66Met polymorphism in Chinese Han. The Journal of clinical psychiatry. 2008 Jul; 69(7):1104-11. doi: 10.4088/jcp.v69n0710. [PMID: 18505307]
  • E Papadopoulou, K Anagnostopoulos, G Tripsianis, I Tentes, S Kakolyris, G Galazios, E Sivridis, K Simopoulos, A Kortsaris. Evaluation of predictive and prognostic significance of serum TGF-beta1 levels in breast cancer according to HER-2 codon 655 polymorphism. Neoplasma. 2008; 55(3):229-38. doi: NULL. [PMID: 18348656]
  • E Papadopoulou, G Tripsianis, K Anagnostopoulos, I Tentes, S Kakolyris, G Galazios, E Sivridis, K Simopoulos, A Kortsaris. The influence of serum HER-2 levels and HER-2 codon 655 polymorphism on breast cancer outcome. Neoplasma. 2008; 55(2):113-21. doi: NULL. [PMID: 18237248]
  • Ricardo Dávila, Mercedes Zumárraga, Nieves Basterreche, Aurora Arrúe, M Isabel Zamalloa, Juan B Anguiano. Influence of the catechol-O-methyltransferase Val108/158Met polymorphism on the plasma concentration of catecholamine metabolites and on clinical features in type I bipolar disorder--a preliminary report. Journal of affective disorders. 2006 Jun; 92(2-3):277-81. doi: 10.1016/j.jad.2006.02.009. [PMID: 16542735]