20-Hydroxy-6Z,15Z-eicosadienoic acid (BioDeep_00001883897)
代谢物信息卡片
化学式: C20H36O3 (324.26643060000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CCCC=CCCCCC(=O)O)CCCC=CCCCCO
InChI: InChI=1S/C20H36O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h8-11,21H,1-7,12-19H2,(H,22,23)/b10-8-,11-9-
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Victor Garcia, Jennifer Cheng, Adam Weidenhammer, Yan Ding, Cheng-Chia Wu, Fan Zhang, Katherine Gotlinger, John R Falck, Michal L Schwartzman. Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS.
Prostaglandins & other lipid mediators.
2015 Jan; 116-117(?):124-30. doi:
10.1016/j.prostaglandins.2014.12.001. [PMID: 25526688] - YiLin Ren, Martin A D'Ambrosio, Jeffrey L Garvin, Edward L Peterson, Oscar A Carretero. Mechanism of impaired afferent arteriole myogenic response in Dahl salt-sensitive rats: role of 20-HETE.
American journal of physiology. Renal physiology.
2014 Sep; 307(5):F533-8. doi:
10.1152/ajprenal.00283.2014. [PMID: 24990891] - Uwe Hoff, Ivo Lukitsch, Lyubov Chaykovska, Mechthild Ladwig, Cosima Arnold, Vijay L Manthati, T Florian Fuller, Wolfgang Schneider, Maik Gollasch, Dominik N Muller, Bert Flemming, Erdmann Seeliger, Friedrich C Luft, John R Falck, Duska Dragun, Wolf-Hagen Schunck. Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.
Kidney international.
2011 Jan; 79(1):57-65. doi:
10.1038/ki.2010.377. [PMID: 20962739] - Richard J Roman, Talha Akbulut, Frank Park, Kevin R Regner. 20-HETE in acute kidney injury.
Kidney international.
2011 Jan; 79(1):10-3. doi:
10.1038/ki.2010.396. [PMID: 21157458] - Komal Sodhi, Cheng-Chia Wu, Jennifer Cheng, Katherine Gotlinger, Kazuyoshi Inoue, Mohan Goli, John R Falck, Nader G Abraham, Michal L Schwartzman. CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.
Hypertension (Dallas, Tex. : 1979).
2010 Nov; 56(5):871-8. doi:
10.1161/hypertensionaha.110.154559. [PMID: 20837888] - Meetha Medhora, Yuenmu Chen, Stephanie Gruenloh, Daniel Harland, Sreedhar Bodiga, Jacek Zielonka, Debebe Gebremedhin, Ying Gao, John R Falck, Siddam Anjaiah, Elizabeth R Jacobs. 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
American journal of physiology. Lung cellular and molecular physiology.
2008 May; 294(5):L902-11. doi:
10.1152/ajplung.00278.2007. [PMID: 18296498] - Hong Wang, Jeffrey L Garvin, John R Falck, YiLin Ren, Steadman S Sankey, Oscar A Carretero. Glomerular cytochrome P-450 and cyclooxygenase metabolites regulate efferent arteriole resistance.
Hypertension (Dallas, Tex. : 1979).
2005 Nov; 46(5):1175-9. doi:
10.1161/01.hyp.0000187531.93389.63. [PMID: 16230518]