(Z)-7-[(1R,2R,5S)-2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid (BioDeep_00001883642)
代谢物信息卡片
化学式: C29H35NO5 (477.25151000000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1COCCN1C2C(C(CC2=O)OCC3=CC=C(C=C3)C4=CC=CC=C4)CCC=CCCC(=O)O
InChI: InChI=1S/C29H35NO5/c31-26-20-27(35-21-22-12-14-24(15-13-22)23-8-4-3-5-9-23)25(10-6-1-2-7-11-28(32)33)29(26)30-16-18-34-19-17-30/h1-5,8-9,12-15,25,27,29H,6-7,10-11,16-21H2,(H,32,33)/b2-1-/t25-,27-,29+/m0/s1
描述信息
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Agnes Rasmuson, Anna Kock, Ole Martin Fuskevåg, Björn Kruspig, Jaione Simón-Santamaría, Vladimir Gogvadze, John Inge Johnsen, Per Kogner, Baldur Sveinbjörnsson. Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma.
PloS one.
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Peptides.
2005 May; 26(5):707-11. doi:
10.1016/j.peptides.2005.01.010. [PMID: 15808899] - Richard J Davis, Colin E Murdoch, Mozam Ali, Stuart Purbrick, Rivka Ravid, Gordon S Baxter, Nick Tilford, Robert L G Sheldrick, Kenneth L Clark, Robert A Coleman. EP4 prostanoid receptor-mediated vasodilatation of human middle cerebral arteries.
British journal of pharmacology.
2004 Feb; 141(4):580-5. doi:
10.1038/sj.bjp.0705645. [PMID: 14744815] - Teresa Sanchez, Juan Jose Moreno. Role of EP(1) and EP(4) PGE(2) subtype receptors in serum-induced 3T6 fibroblast cycle progression and proliferation.
American journal of physiology. Cell physiology.
2002 Feb; 282(2):C280-8. doi:
10.1152/ajpcell.00128.2001. [PMID: 11788339] - T L Davis, N A Sharif. Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor.
British journal of pharmacology.
2000 Aug; 130(8):1919-26. doi:
10.1038/sj.bjp.0703525. [PMID: 10952683] - M Abramovitz, M Adam, Y Boie, M Carrière, D Denis, C Godbout, S Lamontagne, C Rochette, N Sawyer, N M Tremblay, M Belley, M Gallant, C Dufresne, Y Gareau, R Ruel, H Juteau, M Labelle, N Ouimet, K M Metters. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.
Biochimica et biophysica acta.
2000 Jan; 1483(2):285-93. doi:
10.1016/s1388-1981(99)00164-x. [PMID: 10634944] - Y Boie, R Stocco, N Sawyer, D M Slipetz, M D Ungrin, F Neuschäfer-Rube, G P Püschel, K M Metters, M Abramovitz. Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes.
European journal of pharmacology.
1997 Dec; 340(2-3):227-41. doi:
10.1016/s0014-2999(97)01383-6. [PMID: 9537820] - N Nishigaki, M Negishi, A Honda, Y Sugimoto, T Namba, S Narumiya, A Ichikawa. Identification of prostaglandin E receptor 'EP2' cloned from mastocytoma cells EP4 subtype.
FEBS letters.
1995 May; 364(3):339-41. doi:
10.1016/0014-5793(95)00421-5. [PMID: 7758593] - C Wilken, E A Van Kirk, R G Slaughter, T H Ji, W J Murdoch. Increased production of ovarian thromboxane in gonadotropin-treated immature rats: relationship to the ovulatory process.
Prostaglandins.
1990 Dec; 40(6):637-46. doi:
10.1016/0090-6980(90)90008-j. [PMID: 2093939] - J Geoffroy, D Benzoni, J Sassard. Antihypertensive effect of thromboxane A2 receptor blockade in genetically hypertensive rats of the Lyon strain.
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