Azithromycin Dihydrate (BioDeep_00001883330)
代谢物信息卡片
Azithromycin Dihydrate
化学式: C38H76N2O14 (784.5296276)
中文名称: 阿奇霉素 二水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O.O.O
InChI: /m1../s1
描述信息
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Homa Fazeli Kakhki, Mahboobeh Ghasemzadeh Rahbardar, Bibi Marjan Razavi, Mahmoud Reza Heidari, Hossein Hosseinzadeh. Preventive and therapeutic effects of azithromycin on acrylamide-induced neurotoxicity in rats.
Neurotoxicology.
2024 Jan; 100(?):47-54. doi:
10.1016/j.neuro.2023.11.011. [PMID: 38043637] - Sara Kamanmalek, Jacelyn Rice-Boayue. Development of a national antibiotic multimetric index for identifying watersheds vulnerable to antibiotic pollution.
Environmental pollution (Barking, Essex : 1987).
2023 Dec; 339(?):122670. doi:
10.1016/j.envpol.2023.122670. [PMID: 37813143] - Nia Yuniarti, Yoki Yulizar. Chitosan Nanoparticles Modified by Anredera cordifolia (Ten.) Steenis Leaf Extract for Enhancement of Azithromycin Encapsulation Efficiency and Loading Capacity: In vitro Drug Release Study.
Journal of pharmaceutical sciences.
2023 12; 112(12):3164-3174. doi:
10.1016/j.xphs.2023.07.021. [PMID: 37506767] - Juan C Durán-Álvarez, Blanca Prado, Rodolfo Zanella, Mario Rodríguez, Suhaila Díaz. Wastewater surveillance of pharmaceuticals during the COVID-19 pandemic in Mexico City and the Mezquital Valley: A comprehensive environmental risk assessment.
The Science of the total environment.
2023 Nov; 900(?):165886. doi:
10.1016/j.scitotenv.2023.165886. [PMID: 37524191] - Xiaoqian Lu, Tongyun Mao, Yongguo Dai, Lu Zhu, Xiaomin Li, Ying Ao, Hui Wang. Azithromycin exposure during pregnancy disturbs the fetal development and its characteristic of multi-organ toxicity.
Life sciences.
2023 Sep; 329(?):121985. doi:
10.1016/j.lfs.2023.121985. [PMID: 37516432] - Huajun Zhang, Congling Sun, Zhongcui Yu. Effect of azithromycin sequential therapy combined with budesonide nebulization on chest CT changes in children with mycoplasma pneumonia.
Minerva gastroenterology.
2023 09; 69(3):447-449. doi:
10.23736/s2724-5985.23.03373-9. [PMID: 37013384] - Nicolas Vallet, Maud Salmona, Jeanne Malet-Villemagne, Maxime Bredel, Louise Bondeelle, Simon Tournier, Séverine Mercier-Delarue, Stéphane Cassonnet, Brian Ingram, Régis Peffault de Latour, Anne Bergeron, Gérard Socié, Jérome Le Goff, Patricia Lepage, David Michonneau. Circulating T cell profiles associate with enterotype signatures underlying hematological malignancy relapses.
Cell host & microbe.
2023 Jul; ?(?):. doi:
10.1016/j.chom.2023.06.009. [PMID: 37463582] - Farah Al-Marzooq, Akela Ghazawi, Lana Daoud, Saeed Tariq. Boosting the Antibacterial Activity of Azithromycin on Multidrug-Resistant Escherichia coli by Efflux Pump Inhibition Coupled with Outer Membrane Permeabilization Induced by Phenylalanine-Arginine β-Naphthylamide.
International journal of molecular sciences.
2023 May; 24(10):. doi:
10.3390/ijms24108662. [PMID: 37240007] - Mamadou Niang, John F Reichard, Andrew Maier, Glenn Talaska, Jun Ying, Jorge Santo Domingo, Eunice Varughese, Laura Boczek, Emma Huff, Tiina Reponen. Ciprofloxacin and azithromycin resistant bacteria in a wastewater treatment plant.
Journal of occupational and environmental hygiene.
2023 Apr; ?(?):1-12. doi:
10.1080/15459624.2023.2205485. [PMID: 37084403] - Yun Song, Wenhuan Fu, Youzhi Zhang, Doudou Huang, Jian Wu, Shuangmei Tong, Mingkang Zhong, Huifang Cao, Bin Wang. Azithromycin ameliorated cigarette smoke-induced airway epithelial barrier dysfunction by activating Nrf2/GCL/GSH signaling pathway.
Respiratory research.
2023 Mar; 24(1):69. doi:
10.1186/s12931-023-02375-9. [PMID: 36879222] - Weizhen Zhang, Hengfeng Miao, Jing Liu, Hanqi Wu, Yuting Wang, Peng Gu, Ningfei Lei, Kunlun Yang, Zheng Zheng, Qi Li. Response of submerged macrophytes and biofilms to coexisting azithromycin and tetracycline: Antibiotic resistance genes removal, toxicity assessment and microbial properties.
Aquatic toxicology (Amsterdam, Netherlands).
2023 Jan; 256(?):106410. doi:
10.1016/j.aquatox.2023.106410. [PMID: 36724685] - Mohsen G Alrashedi, Ahmed Shaker Ali, Osama Abdelhakim Ahmed, Ibrahim M Ibrahim. Local Delivery of Azithromycin Nanoformulation Attenuated Acute Lung Injury in Mice.
Molecules (Basel, Switzerland).
2022 Nov; 27(23):. doi:
10.3390/molecules27238293. [PMID: 36500388] - Farzad Mirzaie, Fatemeh Teymori, Seyedehfatemeh Shahcheragh, Sina Dobaradaran, Hosein Arfaeinia, Raheleh Kafaei, Soleyman Sahebi, Sima Farjadfard, Bahman Ramavandi. Occurrence and distribution of azithromycin in wastewater treatment plants, seawater, and sediments of the northern part of the Persian Gulf around Bushehr port: A comparison with Pre-COVID 19 pandemic.
Chemosphere.
2022 Nov; 307(Pt 4):135996. doi:
10.1016/j.chemosphere.2022.135996. [PMID: 35970214] - Hongxia Wang, Meixiang Zhao, Shijian Liu, Xuefeng Wang. Efficacy and safety of reduning injection combined with azithromycin in the treatment of mycoplasma pneumonia among children: A systematic review and meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Nov; 106(?):154402. doi:
10.1016/j.phymed.2022.154402. [PMID: 36029644] - Moslem Daliri, Salome Martinez-Morcillo, Moslem Sharifinia, Gholamali Javdan, Mehrzad Keshavarzifard. Occurrence and ecological risk assessment of antibiotic residues in urban wastewater discharged into the coastal environment of the Persian Gulf (the case of Bandar Abbas).
Environmental monitoring and assessment.
2022 Oct; 194(12):905. doi:
10.1007/s10661-022-10579-7. [PMID: 36253567] - Jinli Wang, Siya Li, Jinwu Meng, Jinyue Zhu, Tianxin Qiu, Wenjia Wang, Jinxue Ding, Zhenguang Liu, Kun Li, Mujahid Lqbal, Deyun Wang, Yi Wu, Jiaguo Liu. Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study.
Veterinary research.
2022 Oct; 53(1):83. doi:
10.1186/s13567-022-01088-z. [PMID: 36224607] - Jing Zheng, Yuwen Zhang, Suxin Zhang. Sustained release of azithromycin from lipid liquid-crystalline nanoparticles laden in situ gel for the treatment of periodontitis: In vitro and efficacy study.
Journal of biomaterials applications.
2022 09; 37(3):482-492. doi:
10.1177/08853282221095395. [PMID: 35499959] - Xuejing Gu, Rongrong Gao, Yanli Li, Jiali Liu, Yan Wu, Hui Xu. Combination effect of azithromycin with TCM preparation Xiyanping injection against Klebsiella pneumoniae infection in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Sep; 104(?):154332. doi:
10.1016/j.phymed.2022.154332. [PMID: 35853301] - Seiya Hanamoto, Ryoko Yamamoto-Ikemoto. In-stream sorption of azithromycin and levofloxacin in a river receiving sewage treatment plant effluent.
Environmental pollution (Barking, Essex : 1987).
2022 Aug; 307(?):119568. doi:
10.1016/j.envpol.2022.119568. [PMID: 35661806] - Ding Huang, Sha Chen, Yanqing Cai, Liye Shi, Yiru Shi, Min Zeng, Weiwei Cheng, Jian Zhang, Hongjie Pan. Adjunctive azithromycin prophylaxis protects women from uterine cesarean scar defect: A randomized controlled trial.
Acta obstetricia et gynecologica Scandinavica.
2022 08; 101(8):889-900. doi:
10.1111/aogs.14387. [PMID: 35645037] - Jing-Chen Tian, Xuan-Ling Zhang, Jian-Rong Cui, Xin-Gang Li. Impact of Azithromycin on Forsythiaside Pharmacokinetics in Rats: A Population Modeling Method.
Current medical science.
2022 Aug; 42(4):863-870. doi:
10.1007/s11596-022-2596-2. [PMID: 35678908] - Xing Li, Shizhang Wei, Xiao Ma, Haotian Li, Manyi Jing, Honghong Liu, Yanling Zhao. Efficacy and safety of Tanreqing injection combined with antibiotics against Streptococcus pneumoniae pneumonia: A systematic review and meta-analysis.
Journal of clinical pharmacy and therapeutics.
2022 Aug; 47(8):1159-1172. doi:
10.1111/jcpt.13706. [PMID: 35712904] - Yu Hu, Qingqing Zhu, Yawei Wang, Chunyang Liao, Guibin Jiang. A short review of human exposure to antibiotics based on urinary biomonitoring.
The Science of the total environment.
2022 Jul; 830(?):154775. doi:
10.1016/j.scitotenv.2022.154775. [PMID: 35339554] - Timothy Arthur Chandos Snow, Alessia Longobardo, David Brealey, Jim Down, Giovanni Satta, Mervyn Singer, Nishkantha Arulkumaran. Beneficial ex vivo immunomodulatory and clinical effects of clarithromycin in COVID-19.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2022 Jul; 28(7):948-954. doi:
10.1016/j.jiac.2022.04.001. [PMID: 35440370] - Muhammad Morshed, Min-Kuang Lee, Jonathan Laley, Darrel Cook, Annie Mak, Navdeep Chahil, Venessa Ryan, Carolyn Montgomery, Sylvia Makaroff, Sarah Malleson, Barbra Arnold, Troy Grennan, Jason Wong, Mel Krajden. British Columbia's Experience after Implementation of the Treponema pallidum Reverse Algorithm and PCR Detection, 2015 to 2020.
Microbiology spectrum.
2022 06; 10(3):e0068622. doi:
10.1128/spectrum.00686-22. [PMID: 35658597] - Mostafa F Al-Hakkani, Gamal A Gouda, Sedky H A Hassan, Mahmoud M A Mohamed, Adham M Nagiub. Environmentally azithromycin pharmaceutical wastewater management and synergetic biocompatible approaches of loaded azithromycin@hematite nanoparticles.
Scientific reports.
2022 Jun; 12(1):10970. doi:
10.1038/s41598-022-14997-y. [PMID: 35768496] - Francesca Cappelli, Orietta Longoni, Jacopo Rigato, Michele Rusconi, Alberto Sala, Igor Fochi, Maria Teresa Palumbo, Stefano Polesello, Claudio Roscioli, Franco Salerno, Fabrizio Stefani, Roberta Bettinetti, Sara Valsecchi. Suspect screening of wastewaters to trace anti-COVID-19 drugs: Potential adverse effects on aquatic environment.
The Science of the total environment.
2022 Jun; 824(?):153756. doi:
10.1016/j.scitotenv.2022.153756. [PMID: 35151733] - Andrew S Kao, Chandima J Herath, Rana Ismail, Malitha E Hettiarachchi. The Triad of Legionnaires' Disease, Rhabdomyolysis, and Acute Kidney Injury: A Case Report.
The American journal of case reports.
2022 Jun; 23(?):e936264. doi:
10.12659/ajcr.936264. [PMID: 35655418] - Ryo Yonezawa, Tomiko Sunaga. Signal of safety due to adverse drug reactions induced by tacrolimus with or without azithromycin.
Transplant infectious disease : an official journal of the Transplantation Society.
2022 Jun; 24(3):e13833. doi:
10.1111/tid.13833. [PMID: 35385596] - Clifford TeBay, Jeffrey R McArthur, Melissa Mangala, Nicholas Kerr, Stewart Heitmann, Matthew D Perry, Monique J Windley, Jamie I Vandenberg, Adam P Hill. Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.
British journal of pharmacology.
2022 06; 179(11):2631-2646. doi:
10.1111/bph.15757. [PMID: 34837219] - Maria F Fuentes-Gonzalez, Alberto Ordinola Navarro, Zully Carmona-Aguilera, Carlos A Hernández-Jimenez, Gustavo M Benitez-Altamirano, Luis D Beltran-Ontiveros, Cesar Lopez-Vejar, Juan P Ramirez-Hinojosa, Olga Vera-Lastra, Bruno A Lopez Luis. Outpatient prescription patterns of COVID-19 drugs in the metropolitan area of Mexico City.
Family practice.
2022 05; 39(3):515-518. doi:
10.1093/fampra/cmab167. [PMID: 34910137] - Joyce F Braam, Alje P van Dam, Sylvia M Bruisten, Martijn S van Rooijen, Henry J C de Vries, Maarten F Schim van der Loeff, Clarissa E Vergunst. Macrolide-Resistant Mycoplasma genitalium Impairs Clinical Improvement of Male Urethritis After Empirical Treatment.
Sexually transmitted diseases.
2022 05; 49(5):360-367. doi:
10.1097/olq.0000000000001591. [PMID: 34962241] - Elettra Fallani, Fabio Cevenini, Pietro Enea Lazzerini, Annalisa Verdini, Simona Saponara. Off-Label Use of Hydroxychloroquine in COVID-19: Analysis of Reports of Suspected Adverse Reactions From the Italian National Network of Pharmacovigilance.
Journal of clinical pharmacology.
2022 05; 62(5):646-655. doi:
10.1002/jcph.2006. [PMID: 34802170] - Zohreh Tamanai-Shacoori, Sandrine Le Gall-David, Fouzia Moussouni, Alaa Sweidan, Elisabeth Polard, Latifa Bousarghin, Anne Jolivet-Gougeon. SARS-CoV-2 and Prevotella spp.: friend or foe? A systematic literature review.
Journal of medical microbiology.
2022 May; 71(5):. doi:
10.1099/jmm.0.001520. [PMID: 35511246] - Toussaint Rouamba, Esperance Ouédraogo, Houreratou Barry, Nobila Valentin Yaméogo, Apoline Sondo, Rainatou Boly, Jacques Zoungrana, Abdoul Risgou Ouédraogo, Marc Christian Tahita, Armel Poda, Arnaud Eric Diendéré, Abdoul-Salam Ouedraogo, Innocent Valea, Isidore Traoré, Zekiba Tarnagda, Maxime K Drabo, Halidou Tinto. Assessment of Recovery Time, Worsening, and Death among Inpatients and Outpatients with COVID-19, Treated with Hydroxychloroquine or Chloroquine plus Azithromycin Combination in Burkina Faso.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2022 May; 118(?):224-229. doi:
10.1016/j.ijid.2022.02.034. [PMID: 35227869] - Rehab Magdy, Ragaey A Eid, Wael Fathy, Manar M Abdel-Aziz, Raghda E Ibrahim, Ahmed Yehia, Mostafa S Sheemy, Mona Hussein. Characteristics and Risk Factors of Persistent Neuropathic Pain in Recovered COVID-19 Patients.
Pain medicine (Malden, Mass.).
2022 04; 23(4):774-781. doi:
10.1093/pm/pnab341. [PMID: 34931670] - M Mohammed Atiyah, H Shnawa Jasim, H Mohammed Atiyah. Phytochemical Screening and Antibacterial Activities of Aqueous and Alcoholic Extracts of Averrhoa bilimbi Leaf against Bacteria Isolated from Oral Cavity.
Archives of Razi Institute.
2022 Apr; 77(2):923-928. doi:
10.22092/ari.2022.357207.1996. [PMID: 36284968] - Michael L Behal, Jonny L Nguyen, Xilong Li, David J Feola, Javier A Neyra, Alexander H Flannery. Azithromycin and Major Adverse Kidney Events in Critically Ill Patients With Sepsis-Associated Acute Kidney Injury.
Shock (Augusta, Ga.).
2022 04; 57(4):479-485. doi:
10.1097/shk.0000000000001883. [PMID: 34731096] - Ibrahim Franklyn Kamara, Ajay M V Kumar, Anna Maruta, Bobson Derrick Fofanah, Charles Kuria Njuguna, Steven Shongwe, Francis Moses, Sia Morenike Tengbe, Joseph Sam Kanu, Sulaiman Lakoh, Alie H D Mansaray, Kalaiselvi Selvaraj, Mohammed Khogali, Rony Zachariah. Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020-2021: Practice Does Not Follow Policy.
International journal of environmental research and public health.
2022 03; 19(7):. doi:
10.3390/ijerph19074005. [PMID: 35409687] - Mike Marvin Ruth, Jelmer Raaijmakers, Erik van den Hombergh, Rob Aarnoutse, Elin M Svensson, Budi O Susanto, Ulrika S H Simonsson, Heiman Wertheim, Wouter Hoefsloot, Jakko van Ingen. Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2022 Mar; 28(3):448.e1-448.e7. doi:
10.1016/j.cmi.2021.07.015. [PMID: 34332109] - Saeed Khoshnood, Maryam Shirani, Amine Dalir, Melika Moradi, Mohammad Hossein Haddadi, Nourkhoda Sadeghifard, Faezeh Sabet Birjandi, Ilya Yashmi, Mohsen Heidary. Antiviral effects of azithromycin: A narrative review.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Mar; 147(?):112682. doi:
10.1016/j.biopha.2022.112682. [PMID: 35131658] - Amy Crawford-Faucher. Antibiotics for the Treatment of COVID-19.
American family physician.
2022 03; 105(3):237-238. doi:
NULL. [PMID: 35289561] - Brit Long, Michael Gottlieb. Azithromycin for Treatment of COVID-19.
American family physician.
2022 03; 105(3):Online. doi:
NULL. [PMID: 35289584] - Pietro Ferrara, Luciana Albano. Azithromycin Has Been Flying Off the Shelves: The Italian Lesson Learnt from Improper Use of Antibiotics against COVID-19.
Medicina (Kaunas, Lithuania).
2022 Mar; 58(3):. doi:
10.3390/medicina58030363. [PMID: 35334539] - Marco Schiavone, Alessio Gasperetti, Elisa Gherbesi, Luca Bergamaschi, Roberto Arosio, Gianfranco Mitacchione, Maurizio Viecca, Giovanni B Forleo. Arrhythmogenic Risk and Mechanisms of QT-Prolonging Drugs to Treat COVID-19.
Cardiac electrophysiology clinics.
2022 03; 14(1):95-104. doi:
10.1016/j.ccep.2021.10.009. [PMID: 35221089] - Maicon Falavigna, Karlyse Claudino Belli, Alexandre Naime Barbosa, Alexandre Prehn Zavascki, Ana Catharina de Seixas Santos Nastri, Christiane Machado Santana, Cinara Stein, Débora Dalmas Gräf, Flavio Adsuara Cadegiani, Hélio Penna Guimarães, José Tadeu Monteiro, Juliana Carvalho Ferreira, Luciano Cesar Pontes de Azevedo, Marcelo Mihailenko Chaves Magri, Marcone Lima Sobreira, Maria Beatriz Gandra de Souza Dias, Maura Salaroli de Oliveira, Mirian de Freitas Dal Ben Corradi, Regis Rosa, Ricardo Souza Heinzelmann, Rosemeri Maurici da Silva, Rubens Belfort Junior, Sergio Cimerman, Verônica Colpani, Viviane Cordeiro Veiga, Carlos Roberto Ribeiro de Carvalho. Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT).
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.
2022 Mar; 26(2):102347. doi:
10.1016/j.bjid.2022.102347. [PMID: 35341739] - Yongli Zhang, Luna Ge, Guanhua Song, Ruojia Zhang, Shufeng Li, Haojun Shi, Hongchang Zhang, Yi Li, Jihong Pan, Lin Wang, Jinxiang Han. Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
British journal of pharmacology.
2022 03; 179(6):1201-1219. doi:
10.1111/bph.15714. [PMID: 34664264] - Hao Luo, Wentao Chen, Zhida Mai, Jianjiang Yang, Xiaomian Lin, Lihong Zeng, Yuying Pan, Qinghui Xie, Qingqing Xu, Xiaoxiao Li, Yiwen Liao, Zhanqin Feng, Jiangli Ou, Xiaolin Qin, Heping Zheng. Development and application of Cas13a-based diagnostic assay for Neisseria gonorrhoeae detection and azithromycin resistance identification.
The Journal of antimicrobial chemotherapy.
2022 02; 77(3):656-664. doi:
10.1093/jac/dkab447. [PMID: 34894246] - Sinem Civriz Bozdağ, Güldane Cengiz Seval, İpek Yönal Hindilerden, Fehmi Hindilerden, Neslihan Andıç, Mustafa Baydar, Lale Aydın Kaynar, Selami Koçak Toprak, Hasan Sami Göksoy, Berrin Balık Aydın, Ufuk Demirci, Ferda Can, Vildan Özkocaman, Eren Gündüz, Zeynep Tuğba Güven, Zübeyde Nur Özkurt, Sinan Demircioğlu, Meral Beksaç, İdris İnce, Umut Yılmaz, Hilal Eroğlu Küçükdiler, Elgün Abishov, Boran Yavuz, Ünal Ataş, Yaşa Gül Mutlu, Volkan Baş, Fahir Özkalemkaş, Hava Üsküdar Teke, Vildan Gürsoy, Serhat Çelik, Rafiye Çiftçiler, Münci Yağcı, Pervin Topçuoğlu, Özcan Çeneli, Hamza Abbasov, Cem Selim, Muhlis Cem Ar, Orhan Kemal Yücel, Sevil Sadri, Canan Albayrak, Ahmet Muzaffer Demir, Nil Güler, Muzaffer Keklik, Hatice Terzi, Ali Doğan, Zeynep Arzu Yegin, Meltem Kurt Yüksel, Soğol Sadri, İrfan Yavaşoğlu, Hüseyin Saffet Beköz, Tekin Aksu, Senem Maral, Veysel Erol, Leylagül Kaynar, Osman İlhan, Ali Zahit Bolaman, Ömür Gökmen Sevindik, Arzu Akyay, Muhit Özcan, Günhan Gürman, Şule Ünal, Yasemin Yavuz, Reyhan Diz Küçükkaya, Güner Hayri Özsan. Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies.
Turkish journal of haematology : official journal of Turkish Society of Haematology.
2022 02; 39(1):43-54. doi:
10.4274/tjh.galenos.2021.2021.0287. [PMID: 34521187] - Moutaz El Kadri, Omar Al Falasi, Rizwan Ahmed, Ahlam Al Awadhi, Zainab Altaha, Amany Hillis, Basheer Panikkaveetil, Sara Abdalla, Honey Ansel Benette, Adhba Almubarak, Mohammed Saifuddin, Yousef Alattar, Abderrahim Oulhaj, Salem AlKaabi. Changes in QTc interval after hydroxychloroquine therapy in patients with COVID-19 infection: a large, retrospective, multicentre cohort study.
BMJ open.
2022 02; 12(2):e051579. doi:
10.1136/bmjopen-2021-051579. [PMID: 35140148] - Kadri Adel, Mosbah Amor, Redissi Alaeddine, Noumi Emira, Alreshidi Mousa, Aouadi Kaïss, Ghannay Siwar, Siddiqui Arif Jamal, Adnan Mohd, Vincenzo De Feo, Snoussi Mejdi. Comparative Computational Analysis of Dirithromycin and Azithromycin in Search for a Potent Drug against COVID-19 caused by SARS-CoV-2: Evidence from molecular docking and dynamic simulation.
Cellular and molecular biology (Noisy-le-Grand, France).
2022 Feb; 67(5):371-386. doi:
10.14715/cmb/2021.67.5.50. [PMID: 35818230] - Luis Ayerbe, Carlos Risco-Risco, Ivo Forgnone, Maria Pérez-Piñar, Salma Ayis. Azithromycin in patients with COVID-19: a systematic review and meta-analysis.
The Journal of antimicrobial chemotherapy.
2022 02; 77(2):303-309. doi:
10.1093/jac/dkab404. [PMID: 34791330] - Antonio Vitiello, Francesco Ferrara. A short focus, azithromycin in the treatment of respiratory viral infection COVID-19: efficacy or inefficacy?.
Immunologic research.
2022 02; 70(1):129-133. doi:
10.1007/s12026-021-09244-x. [PMID: 34739696] - Yingying Peng, Zhe Chen, Yanjiao Li, Qiu Lu, Huanmin Li, Yaowei Han, Dan Sun, Xinmin Li. Combined therapy of Xiaoer Feire Kechuan oral liquid and azithromycin for mycoplasma Pneumoniae pneumonia in children: A systematic review & meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Feb; 96(?):153899. doi:
10.1016/j.phymed.2021.153899. [PMID: 35026500] - Xiaojia Zhu, Yuwei Wang, Yujie Xiao, Qianwen Gao, Li Gao, Wenhui Zhang, Xiaofeng Xin, Kesu Chen, Ujala Srivastava, Vamsi Krishna Murthy Ginjupalli, Michael Cupelli, Pietro Enea Lazzerini, Pier Leopoldo Capecchi, Long Chen, Mohamed Boutjdir. Arrhythmogenic mechanisms of interleukin-6 combination with hydroxychloroquine and azithromycin in inflammatory diseases.
Scientific reports.
2022 01; 12(1):1075. doi:
10.1038/s41598-022-04852-5. [PMID: 35058480] - Anu Kantele, Tinja Lääveri. Extended-spectrum beta-lactamase-producing strains among diarrhoeagenic Escherichia coli-prospective traveller study with literature review.
Journal of travel medicine.
2022 Jan; 29(1):. doi:
10.1093/jtm/taab042. [PMID: 33834207] - Huawei Zhao, Jia Zhou, Haimei Lu, Anran Xi, Mengxian Luo, Keer Wang, Hongjie Lv, Huijuan Wang, Ping Wang, Jing Miao, Zhenghao Xu. Azithromycin pretreatment exacerbates atopic dermatitis in trimellitic anhydride-induced model mice accompanied by correlated changes in the gut microbiota and serum cytokines.
International immunopharmacology.
2022 Jan; 102(?):108388. doi:
10.1016/j.intimp.2021.108388. [PMID: 34819259] - Qingchun Zhao, Junbo Yang, Yongmei Sheng, Min Zhuang, Min Qi. Study on the Therapeutic Effect of Azithromycin Combined with Glucocorticoid on Pulmonary Function and Inflammatory Response in Children with Pneumonia.
Journal of healthcare engineering.
2022; 2022(?):5288148. doi:
10.1155/2022/5288148. [PMID: 35388320] - Shaoli Lin, Shiyun Wang, Juan Zhang, Min Zhuang, Zhen Meng, Jianhua Liu. Efficacy of Jiedu Pingsou Decoction Combined with Azithromycin in the Treatment of Children with Mycoplasma Pneumonia and Its Effects on Inflammatory Factors and Immune Function.
Journal of healthcare engineering.
2022; 2022(?):9102727. doi:
10.1155/2022/9102727. [PMID: 35368961] - Qian Tang, Shuangqing Li, Chengjie Fang, Haining Yu. Evaluating the reparative effects and the mechanism of action of docosahexaenoic acid on azithromycin-induced lipid metabolism dysfunction.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Jan; 159(?):112699. doi:
10.1016/j.fct.2021.112699. [PMID: 34838675] - Maxime Cochin, Franck Touret, Jean-Sélim Driouich, Gregory Moureau, Paul-Rémi Petit, Caroline Laprie, Caroline Solas, Xavier de Lamballerie, Antoine Nougairède. Hydroxychloroquine and azithromycin used alone or combined are not effective against SARS-CoV-2 ex vivo and in a hamster model.
Antiviral research.
2022 01; 197(?):105212. doi:
10.1016/j.antiviral.2021.105212. [PMID: 34838583] - Ahmed E Abou Warda, Mahmoud Tammam, Rabab A El-Gazar, Rania M Sarhan, Sayed Gaber. Hydroxychloroquine and Azithromycin Combination in the Management of COVID-19 Infection: Safety and Effectiveness Challenges.
Current drug safety.
2022; 17(2):143-151. doi:
10.2174/1574886316666210727152609. [PMID: 34315385] - Noreen Nasir, Salma Tajuddin, Sarah Khaskheli, Naveera Khan, Hammad Niamatullah, Nosheen Nasir. Clinical outcomes of immunomodulatory therapies in the management of COVID-19: A tertiary-care experience from Pakistan.
PloS one.
2022; 17(1):e0262608. doi:
10.1371/journal.pone.0262608. [PMID: 35085312] - Wooyoung Hong, Yu-Kyung Park, Bong-Ok Kim, Sung Kyu Park, Jiin Shin, Soon-Pyo Jang, Hea-Woon Park, Wonjong Yang, Joonyoung Jang, Soon-Woo Jang, Tae-Ho Hwang. Use of combined treatment of 3rd-generation cephalosporin, azithromycin and antiviral agents on moderate SARs-CoV-2 patients in South Korea: A retrospective cohort study.
PloS one.
2022; 17(5):e0267645. doi:
10.1371/journal.pone.0267645. [PMID: 35507600] - Jiuyang Xu, Bin Cao. Lessons learnt from hydroxychloroquine/azithromycin in treatment of COVID-19.
The European respiratory journal.
2022 01; 59(1):. doi:
10.1183/13993003.02002-2021. [PMID: 34326192] - Elif Sargin Altunok, Celal Satici, Veysel Dinc, Sadettin Kamat, Mustafa Alkan, Mustafa Asim Demirkol, Ilkim Deniz Toprak, Muhammed Emin Kostek, Semih Yazla, Sinem Nihal Esatoglu. Comparison of demographic and clinical characteristics of hospitalized COVID-19 patients with severe/critical illness in the first wave versus the second wave.
Journal of medical virology.
2022 01; 94(1):291-297. doi:
10.1002/jmv.27319. [PMID: 34491575] - Andrea L Schaffer, David Henry, Helga Zoega, Julian H Elliott, Sallie-Anne Pearson. Changes in dispensing of medicines proposed for re-purposing in the first year of the COVID-19 pandemic in Australia.
PloS one.
2022; 17(6):e0269482. doi:
10.1371/journal.pone.0269482. [PMID: 35704621] - Ahmed M Kamel, Mona S A Monem, Nour A Sharaf, Nada Magdy, Samar F Farid. Efficacy and safety of azithromycin in Covid-19 patients: A systematic review and meta-analysis of randomized clinical trials.
Reviews in medical virology.
2022 01; 32(1):e2258. doi:
10.1002/rmv.2258. [PMID: 34077600] - Muhammad M AbdelGhaffar, Dalia Omran, Ahmed Elgebaly, Eshak I Bahbah, Shimaa Afify, Mohamed AlSoda, Mohamed El-Shiekh, Enass S ElSayed, Soha S Shaaban, Samah AbdelHafez, Khaled Elkelany, Ayman A Eltayar, Omnia S Ali, Lamiaa Kamal, Ahmed M Heiba, Ahmad El Askary, Hend Ibrahim Shousha. Prediction of mortality in hospitalized Egyptian patients with Coronavirus disease-2019: A multicenter retrospective study.
PloS one.
2022; 17(1):e0262348. doi:
10.1371/journal.pone.0262348. [PMID: 35015782] - Gregory A Ballash, Anca Baesu, Seungjun Lee, Molly C Mills, Dixie F Mollenkopf, S Mažeika P Sullivan, Jiyoung Lee, Stephen Bayen, Thomas E Wittum. Fish as sentinels of antimicrobial resistant bacteria, epidemic carbapenemase genes, and antibiotics in surface water.
PloS one.
2022; 17(9):e0272806. doi:
10.1371/journal.pone.0272806. [PMID: 36054112] - Enrico Baldi, Roberto Rordorf, Lucrezia Masiello, Sabato D'Amore, Stefano Ghio, Elena Maria Seminari, Federica Melazzini, Elia Fraolini, Stefano Perlini, Guido Tavazzi, Alessandro Vicentini. QTc prolongation and mortality in SARS-2-CoV-infected patients treated with azithromycin and hydroxychloroquine.
Journal of cardiovascular medicine (Hagerstown, Md.).
2022 01; 23(1):e21-e23. doi:
10.2459/jcm.0000000000001238. [PMID: 34341313] - María G Español, Renee V Gardner, Minelys M Alicea-Marrero, Gisela Marrero-Rivera, Tamara Bradford, Dana M LeBlanc, María C Velez. Multisystem Inflammatory Syndrome in a Pediatric Patient With Sickle Cell Disease and COVID-19: A Case Report.
Journal of pediatric hematology/oncology.
2022 Jan; 44(1):e134-e137. doi:
10.1097/mph.0000000000002191. [PMID: 34001792] - Nikolina Bogdanić, Loris Močibob, Toni Vidović, Ana Soldo, Josip Begovać. Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020.
PloS one.
2022; 17(2):e0263437. doi:
10.1371/journal.pone.0263437. [PMID: 35108332] - Zhijing Zhao, Mengyu Guo, Xiaona Xu, Yue Hu, Dongmei Liu, Chunxia Wang, Xinwei Liu, Yongwei Li. In Vitro Synergistic Inhibitory Activity of Natural Alkaloid Berberine Combined with Azithromycin against Alginate Production by Pseudomonas aeruginosa PAO1.
Oxidative medicine and cellular longevity.
2022; 2022(?):3858500. doi:
10.1155/2022/3858500. [PMID: 36124086] - Pradeesh Sivapalan, Charlotte Suppli Ulrik, Therese Sophie Lapperre, Rasmus Dahlin Bojesen, Josefin Eklöf, Andrea Browatzki, Jon Torgny Wilcke, Vibeke Gottlieb, Kjell Erik Julius Håkansson, Casper Tidemandsen, Oliver Tupper, Howraman Meteran, Christina Bergsøe, Eva Brøndum, Uffe Bødtger, Daniel Bech Rasmussen, Sidse Graff Jensen, Lars Pedersen, Alexander Jordan, Helene Priemé, Christian Søborg, Ida E Steffensen, Dorthe Høgsberg, Tobias Wirenfeldt Klausen, Martin Steen Frydland, Peter Lange, Asger Sverrild, Muhzda Ghanizada, Filip K Knop, Tor Biering-Sørensen, Jens D Lundgren, Jens-Ulrik Stæhr Jensen. Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial.
The European respiratory journal.
2022 01; 59(1):. doi:
10.1183/13993003.00752-2021. [PMID: 34083403] - Qingling Zhang, Yuqi Zong, Lizhen Yang, Kunran Wang, Yan Wang. Clinical Evaluation and Exploration of Mechanisms for Modified Xiebai Powder or Modified Xiebai Powder Combined with Western Medicine in the Treatment of Pneumonia.
Computational and mathematical methods in medicine.
2022; 2022(?):2287470. doi:
10.1155/2022/2287470. [PMID: 36276995] - Mina T Kelleni. NSAIDs/nitazoxanide/azithromycin repurposed for COVID-19: potential mitigation of the cytokine storm interleukin-6 amplifier via immunomodulatory effects.
Expert review of anti-infective therapy.
2022 01; 20(1):17-21. doi:
10.1080/14787210.2021.1939683. [PMID: 34088250] - Celine Boschi, Marion Le Bideau, Julien Andreani, Sarah Aherfi, Priscilla Jardot, Jeremy Delerce, Mathieu Gendrot, Bruno Pradines, Philippe Colson, Anthony Levasseur, Bernard La Scola. Heterogeneity in susceptibility to hydroxychloroquine of SARS-CoV-2 isolates.
Frontiers in bioscience (Landmark edition).
2021 12; 26(12):1493-1502. doi:
10.52586/5043. [PMID: 34994164] - Miguel de Lemos Neto, Rafael Costa Vieira Alexandre, Rafaela Oliveira Gallart Morra, Juliana Aparecida Souza da Paz, Shana Priscila Coutinho Barroso, Angela Castro Resende, Daniel J M de Medeiros-Lima, Pedro Celso Braga Alexandre. Use of glucocorticoids and azithromycin in the therapy of COVID-19.
Pharmacological reports : PR.
2021 Dec; 73(6):1513-1519. doi:
10.1007/s43440-021-00286-4. [PMID: 34085181] - Mariana Guimarães, Pascal Somville, Maria Vertzoni, Nikoletta Fotaki. Investigating the Critical Variables of Azithromycin Oral Absorption Using In Vitro Tests and PBPK Modeling.
Journal of pharmaceutical sciences.
2021 12; 110(12):3874-3888. doi:
10.1016/j.xphs.2021.09.013. [PMID: 34530004] - Nour K Younis, Rana O Zareef, Ghina Fakhri, Fadi Bitar, Ali H Eid, Mariam Arabi. COVID-19: potential therapeutics for pediatric patients.
Pharmacological reports : PR.
2021 Dec; 73(6):1520-1538. doi:
10.1007/s43440-021-00316-1. [PMID: 34458951] - Paul M Kinsella, Olivia C Smibert, John B Whitlam, Mark Steven, Ricard Masia, Ronak G Gandhi, Camille N Kotton, Natasha E Holmes. Successful use of azithromycin for Escherichia coli-associated renal allograft malakoplakia: a report of two cases.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2021 Dec; 40(12):2627-2631. doi:
10.1007/s10096-021-04270-x. [PMID: 33990891] - Gerald Chi, Sahar Memar Montazerin, Jane J Lee, Syed Hassan A Kazmi, Fahimehalsadat Shojaei, Clara Fitzgerald, C Michael Gibson. Effect of azithromycin and hydroxychloroquine in patients hospitalized with COVID-19: Network meta-analysis of randomized controlled trials.
Journal of medical virology.
2021 Dec; 93(12):6737-6749. doi:
10.1002/jmv.27259. [PMID: 34370328] - Jeremy W Jacobs, Alexa J Siddon. Concurrent COVID-19 and babesiosis in an older, splenectomized patient.
Blood.
2021 11; 138(21):2154. doi:
10.1182/blood.2021013947. [PMID: 34821934] - Pannaporn Thongsuk, Rongpong Plongla, Arsa Thammahong, Jaruwan Tiewsurin, Navaporn Worasilchai, Ariya Chindamporn, Chusana Suankratay. Vascular pythiosis caused by Pythium aphanidermatum: the first case report in Asia.
European journal of medical research.
2021 Nov; 26(1):132. doi:
10.1186/s40001-021-00603-w. [PMID: 34775999] - Li-Ping Han, Han-Yan Xiao, Li-Li Fang. A retrospective study of azithromycin and ceftizoxime for the management of children with Mycoplasma pneumoniae pneumonia.
Medicine.
2021 Nov; 100(44):e27564. doi:
10.1097/md.0000000000027564. [PMID: 34871221] - Hanna Gerlovin, Daniel C Posner, Yuk-Lam Ho, Christopher T Rentsch, Janet P Tate, Joseph T King, Katherine E Kurgansky, Ioana Danciu, Lauren Costa, Franciel A Linares, Ian D Goethert, Daniel A Jacobson, Matthew S Freiberg, Edmon Begoli, Sumitra Muralidhar, Rachel B Ramoni, Georgia Tourassi, J Michael Gaziano, Amy C Justice, David R Gagnon, Kelly Cho. Pharmacoepidemiology, Machine Learning, and COVID-19: An Intent-to-Treat Analysis of Hydroxychloroquine, With or Without Azithromycin, and COVID-19 Outcomes Among Hospitalized US Veterans.
American journal of epidemiology.
2021 11; 190(11):2405-2419. doi:
10.1093/aje/kwab183. [PMID: 34165150] - Xun Sun, Xiao-Ying Ling, Qiu-Yue Xu, Ming-Chen Jiang, Bin Yuan. [Network Meta-analysis of 14 oral Chinese patent medicines combined with Azithromycin in treatment of mycoplasma pneumonia in children].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2021 Nov; 46(22):5958-5976. doi:
10.19540/j.cnki.cjcmm.20210408.501. [PMID: 34951188] - Taher K Eleiwa, Ayman Elmaghrabi, Hend G Helal, Samar N Abdelrahman, Reem H ElSheikh, Abdelrahman M Elhusseiny. Phlyctenular Keratoconjunctivitis in a Patient With COVID-19 Infection.
Cornea.
2021 Nov; 40(11):1502-1504. doi:
10.1097/ico.0000000000002789. [PMID: 34320598] - Mei Yin. Effect of Qingfei Huatan Huoxue Decoction combined with azithromycin on pulmonary function and inflammatory factors in children with Mycoplasma pneumonia.
Pakistan journal of pharmaceutical sciences.
2021 Nov; 34(6(Supplementary)):2317-2323. doi:
. [PMID: 35039269] - Usha Yendrapalli, Hassoun Ali, Jacqueline L Green, Jonathan Edwards. Effects of cardiac toxicity of combination therapy with hydroxychloroquine and azithromycin in COVID-19 patients.
Journal of infection and public health.
2021 Nov; 14(11):1668-1670. doi:
10.1016/j.jiph.2021.09.013. [PMID: 34627063] - Cristhieni Rodrigues, Rodrigo S Freitas-Santos, José Eduardo Levi, Andreza A Senerchia, Ana Tarina A Lopes, Sergio R Santos, Rinaldo F Siciliano, Lígia C Pierrotti. Hydroxychloroquine plus azithromycin early treatment of mild COVID-19 in an outpatient setting: a randomized, double-blinded, placebo-controlled clinical trial evaluating viral clearance.
International journal of antimicrobial agents.
2021 Nov; 58(5):106428. doi:
10.1016/j.ijantimicag.2021.106428. [PMID: 34454044] - Jinli Wang, Jinyue Zhu, Jinwu Meng, Tianxin Qiu, Wenjia Wang, Rui Wang, Jiaguo Liu. Baicalin inhibits biofilm formation by influencing primary adhesion and aggregation phases in Staphylococcus saprophyticus.
Veterinary microbiology.
2021 Nov; 262(?):109242. doi:
10.1016/j.vetmic.2021.109242. [PMID: 34562786] - Liu Ting, W U Li-Ying, Yang Xiao-Mei, Chen Yao, D U Xue-Jiao, Luo Xue-Dan, Zhou Jin, Sui Yi, Zhu Wen-Ting. Curative effect of kangfuyan capsule combined with antibiotic treatment on pelvic inflammatory disease.
Pakistan journal of pharmaceutical sciences.
2021 Nov; 34(6(Special)):2479-2485. doi:
NULL. [PMID: 35039263] - John N Varkey, William H Frishman. Arrhythmogenesis and COVID-19.
Cardiology in review.
2021 Nov; 29(6):289-291. doi:
10.1097/crd.0000000000000407. [PMID: 34261901] - Roberto Alfonso Accinelli, Grisel Jesús Ynga-Meléndez, Juan Alonso León-Abarca, Lidia Marianella López, Juan Carlos Madrid-Cisneros, Juan Diego Mendoza-Saldaña. Hydroxychloroquine / azithromycin in COVID-19: The association between time to treatment and case fatality rate.
Travel medicine and infectious disease.
2021 Nov; 44(?):102163. doi:
10.1016/j.tmaid.2021.102163. [PMID: 34534686] - Lorenzo Guglielmetti, Daniela Aschieri, Irina Kontsevaya, Francesco Calabrese, Alessandra Donisi, Alberto Faggi, Patrizia Ferrante, Elisa Fronti, Laura Gerna, Maria Cristina Leoni, Franco Paolillo, Giovanna Ratti, Alessandro Ruggieri, Daria Sacchini, Marta Scotti, Caterina Valdatta, Marco Stabile, Gloria Taliani, Mauro Codeluppi. Treatment for COVID-19-a cohort study from Northern Italy.
Scientific reports.
2021 10; 11(1):20964. doi:
10.1038/s41598-021-00243-4. [PMID: 34697322] - Blanca Garmendia-Prieto, Pamela Carrillo-García, Javier Gómez-Pavón. QT interval prolongation in geriatric patients treated for SARS-COV-2 infection: OCTA-COVID study.
Medicina clinica.
2021 10; 157(8):e302-e303. doi:
10.1016/j.medcli.2021.03.026. [PMID: 34059357] - Gwendolyn E Wood, Nicole L Jensen, Sabina Astete, Jørgen S Jensen, George E Kenny, Christine M Khosropour, Catherine W Gillespie, Lisa E Manhart, Patricia A Totten. Azithromycin and Doxycycline Resistance Profiles of U.S. Mycoplasma genitalium Strains and Their Association with Treatment Outcomes.
Journal of clinical microbiology.
2021 10; 59(11):e0081921. doi:
10.1128/jcm.00819-21. [PMID: 34406799]