Dehydroergosterol (BioDeep_00001883210)

   

natural product


Metabolite Card


Dehydroergosterol

Formula: C28H42O (394.3235)
Chinese Names:
Spectrum Hits: Top Source () 0%

Molecular Structure

SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(CC=C3C2=CC=C4C3(CCC(C4)O)C)C
InChI: InChI=1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1

Description

A phytosterol consiting of ergostane having double bonds at the 5,6-, 7,8- 9,11- and 22,23-positions as well as a 3beta-hydroxy group.

Synonyms

1 synonym names

Dehydroergosterol



Cross Reference

5 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

53 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

Sub-cellular location Genes


Literature Reference

  • Svetlana V Senik, Nadezhda V Psurtseva, Alexey L Shavarda, Ekaterina R Kotlova. Role of lipids in the thermal plasticity of basidial fungus Favolaschia manipularis. Canadian journal of microbiology. 2019 Dec; 65(12):870-879. doi: 10.1139/cjm-2019-0284. [PMID: 31398296]
  • Kunisato Kuroi, Masatomo Imaizumi, Takashi Miura, Takakazu Nakabayashi. Examination of the association states of dehydroergosterol towards understanding the association structures of sterols in a membrane. Biochemical and biophysical research communications. 2019 07; 515(1):228-233. doi: 10.1016/j.bbrc.2019.05.109. [PMID: 31146916]
  • Theodore L Steck, Yvonne Lange. Transverse distribution of plasma membrane bilayer cholesterol: Picking sides. Traffic (Copenhagen, Denmark). 2018 10; 19(10):750-760. doi: 10.1111/tra.12586. [PMID: 29896788]
  • Zane Berzina, Lukasz M Solanko, Ahmed S Mehadi, Maria Louise V Jensen, Frederik W Lund, Maciej Modzel, Maria Szomek, Katarzyna A Solanko, Alice Dupont, Gitte Krogh Nielsen, Christian W Heegaard, Christer S Ejsing, Daniel Wüstner. Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts. Chemistry and physics of lipids. 2018 07; 213(?):48-61. doi: 10.1016/j.chemphyslip.2018.03.006. [PMID: 29580834]
  • David B Iaea, Shu Mao, Frederik W Lund, Frederick R Maxfield. Role of STARD4 in sterol transport between the endocytic recycling compartment and the plasma membrane. Molecular biology of the cell. 2017 Apr; 28(8):1111-1122. doi: 10.1091/mbc.e16-07-0499. [PMID: 28209730]
  • Mohsen Pourmousa, Tomasz Róg, Risto Mikkeli, Llpo Vattulainen, Lukasz M Solanko, Daniel Wüstner, Nanna Holmgaard List, Jacob Kongsted, Mikko Karttunen. Dehydroergosterol as an analogue for cholesterol: why it mimics cholesterol so well-or does it?. The journal of physical chemistry. B. 2014 Jul; 118(26):7345-57. doi: 10.1021/jp406883k. [PMID: 24893063]
  • João R Robalo, António M T Martins do Canto, A J Palace Carvalho, J P Prates Ramalho, Luís M S Loura. Behavior of fluorescent cholesterol analogues dehydroergosterol and cholestatrienol in lipid bilayers: a molecular dynamics study. The journal of physical chemistry. B. 2013 May; 117(19):5806-19. doi: 10.1021/jp312026u. [PMID: 23597397]
  • Frederick R Maxfield, Daniel Wüstner. Analysis of cholesterol trafficking with fluorescent probes. Methods in cell biology. 2012; 108(?):367-93. doi: 10.1016/b978-0-12-386487-1.00017-1. [PMID: 22325611]
  • Tim P Levine. Lipid traffic: Osh4p makes an unexpected exchange. The Journal of cell biology. 2011 Dec; 195(6):927-9. doi: 10.1083/jcb.201111074. [PMID: 22162132]
  • Maud de Saint-Jean, Vanessa Delfosse, Dominique Douguet, Gaëtan Chicanne, Bernard Payrastre, William Bourguet, Bruno Antonny, Guillaume Drin. Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. The Journal of cell biology. 2011 Dec; 195(6):965-78. doi: 10.1083/jcb.201104062. [PMID: 22162133]
  • Bruno Mesmin, Nina H Pipalia, Frederik W Lund, Trudy F Ramlall, Anna Sokolov, David Eliezer, Frederick R Maxfield. STARD4 abundance regulates sterol transport and sensing. Molecular biology of the cell. 2011 Nov; 22(21):4004-15. doi: 10.1091/mbc.e11-04-0372. [PMID: 21900492]
  • Alexander G Georgiev, David P Sullivan, Michael C Kersting, Jeremy S Dittman, Christopher T Beh, Anant K Menon. Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM. Traffic (Copenhagen, Denmark). 2011 Oct; 12(10):1341-55. doi: 10.1111/j.1600-0854.2011.01234.x. [PMID: 21689253]
  • Leslie A McCauliff, Zhi Xu, Judith Storch. Sterol transfer between cyclodextrin and membranes: similar but not identical mechanism to NPC2-mediated cholesterol transfer. Biochemistry. 2011 Aug; 50(34):7341-7349. doi: 10.1021/bi200574f. [PMID: 21740003]
  • Brad Chazotte. Labeling membranes with fluorescent cholesterols. Cold Spring Harbor protocols. 2011 May; 2011(5):pdb.prot5624. doi: 10.1101/pdb.prot5624. [PMID: 21536756]
  • Daniel Wüstner, Lukasz Solanko, Elena Sokol, Olav Garvik, Zaiguo Li, Robert Bittman, Thomas Korte, Andreas Herrmann. Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol. Chemistry and physics of lipids. 2011 Mar; 164(3):221-35. doi: 10.1016/j.chemphyslip.2011.01.004. [PMID: 21291873]
  • Peter Kohut, Daniel Wüstner, Lucia Hronska, Karl Kuchler, Ivan Hapala, Martin Valachovic. The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: dehydroergosterol fluorescence study. Biochemical and biophysical research communications. 2011 Jan; 404(1):233-8. doi: 10.1016/j.bbrc.2010.11.099. [PMID: 21110944]
  • Daniel Wüstner, Jonathan R Brewer, Luis Bagatolli, Daniel Sage. Potential of ultraviolet wide-field imaging and multiphoton microscopy for analysis of dehydroergosterol in cellular membranes. Microscopy research and technique. 2011 Jan; 74(1):92-108. doi: 10.1002/jemt.20878. [PMID: 21181715]
  • Frederick A Heberle, Jing Wu, Shih Lin Goh, Robin S Petruzielo, Gerald W Feigenson. Comparison of three ternary lipid bilayer mixtures: FRET and ESR reveal nanodomains. Biophysical journal. 2010 Nov; 99(10):3309-18. doi: 10.1016/j.bpj.2010.09.064. [PMID: 21081079]
  • Olav Garvik, Peter Benediktson, Adam Cohen Simonsen, John Hjort Ipsen, Daniel Wüstner. The fluorescent cholesterol analog dehydroergosterol induces liquid-ordered domains in model membranes. Chemistry and physics of lipids. 2009 Jun; 159(2):114-8. doi: 10.1016/j.chemphyslip.2009.03.002. [PMID: 19477318]
  • Liming Qiu, Anthony Lewis, John Como, Mark W Vaughn, Juyang Huang, Pentti Somerharju, Jorma Virtanen, Kwan Hon Cheng. Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers. Biophysical journal. 2009 May; 96(10):4299-307. doi: 10.1016/j.bpj.2009.02.036. [PMID: 19450500]
  • Avery L McIntosh, Barbara P Atshaves, Huan Huang, Adalberto M Gallegos, Ann B Kier, Friedhelm Schroeder. Fluorescence techniques using dehydroergosterol to study cholesterol trafficking. Lipids. 2008 Dec; 43(12):1185-208. doi: 10.1007/s11745-008-3194-1. [PMID: 18536950]
  • Avery L McIntosh, Barbara P Atshaves, Adalberto M Gallegos, Stephen M Storey, Joseph H Reibenspies, Ann B Kier, Edgar Meyer, Friedhelm Schroeder. Structure of dehydroergosterol monohydrate and interaction with sterol carrier protein-2. Lipids. 2008 Dec; 43(12):1165-84. doi: 10.1007/s11745-008-3267-1. [PMID: 19020914]
  • Daniel Wüstner, Nils J Faergeman. Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells. Histochemistry and cell biology. 2008 Nov; 130(5):891-908. doi: 10.1007/s00418-008-0488-6. [PMID: 18787836]
  • Michelle Olsher, Parkson Lee-Gau Chong. Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants. Analytical biochemistry. 2008 Nov; 382(1):1-8. doi: 10.1016/j.ab.2008.07.021. [PMID: 18694720]
  • Nicole Hartwig Petersen, Nils J Faergeman, Nils J Faegeman, Liqing Yu, Daniel Wüstner. Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells. Journal of lipid research. 2008 Sep; 49(9):2023-37. doi: 10.1194/jlr.m800145-jlr200. [PMID: 18523240]
  • Daniel Wüstner. Free-cholesterol loading does not trigger phase separation of the fluorescent sterol dehydroergosterol in the plasma membrane of macrophages. Chemistry and physics of lipids. 2008 Aug; 154(2):129-36. doi: 10.1016/j.chemphyslip.2008.04.009. [PMID: 18534190]
  • Daniel Wüstner, Nils J Faergeman. Chromatic aberration correction and deconvolution for UV sensitive imaging of fluorescent sterols in cytoplasmic lipid droplets. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2008 Aug; 73(8):727-44. doi: 10.1002/cyto.a.20593. [PMID: 18561197]
  • Giacomo Diaz, Barbara Batetta, Francesca Sanna, Sabrina Uda, Camilla Reali, Fabrizio Angius, Marta Melis, Angela Maria Falchi. Lipid droplet changes in proliferating and quiescent 3T3 fibroblasts. Histochemistry and cell biology. 2008 May; 129(5):611-21. doi: 10.1007/s00418-008-0402-2. [PMID: 18297300]
  • Luís M B B Estronca, Maria João Moreno, Winchil L C Vaz. Kinetics and thermodynamics of the association of dehydroergosterol with lipid bilayer membranes. Biophysical journal. 2007 Dec; 93(12):4244-53. doi: 10.1529/biophysj.107.112847. [PMID: 17766353]
  • Daniel Wüstner. Fluorescent sterols as tools in membrane biophysics and cell biology. Chemistry and physics of lipids. 2007 Mar; 146(1):1-25. doi: 10.1016/j.chemphyslip.2006.12.004. [PMID: 17241621]
  • Nina H Pipalia, Mingming Hao, Sushmita Mukherjee, Frederick R Maxfield. Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. Traffic (Copenhagen, Denmark). 2007 Feb; 8(2):130-41. doi: 10.1111/j.1600-0854.2006.00513.x. [PMID: 17156101]
  • Parkson Lee-Gau Chong, Michelle Olsher. Fluorometric assay for detection of sterol oxidation in liposomal membranes. Methods in molecular biology (Clifton, N.J.). 2007; 400(?):145-58. doi: 10.1007/978-1-59745-519-0_10. [PMID: 17951732]
  • Daniel Wüstner. Plasma membrane sterol distribution resembles the surface topography of living cells. Molecular biology of the cell. 2007 Jan; 18(1):211-28. doi: 10.1091/mbc.e06-05-0445. [PMID: 17065557]
  • Avery L McIntosh, Barbara P Atshaves, Huan Huang, Adalberto M Gallegos, Ann B Kier, Friedhelm Schroeder, Hai Xu, Weimin Zhang, Suojin Wang, Jyh-Charn Liu. Multiphoton laser-scanning microscopy and spatial analysis of dehydroergosterol distributions on plasma membrane of living cells. Methods in molecular biology (Clifton, N.J.). 2007; 398(?):85-105. doi: 10.1007/978-1-59745-513-8_8. [PMID: 18214376]
  • Adalberto M Gallegos, Stephen M Storey, Ann B Kier, Friedhelm Schroeder, Judith M Ball. Structure and cholesterol dynamics of caveolae/raft and nonraft plasma membrane domains. Biochemistry. 2006 Oct; 45(39):12100-16. doi: 10.1021/bi0602720. [PMID: 17002310]
  • Mark P Burns, Urule Igbavboa, Lili Wang, W Gibson Wood, Karen Duff. Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice. Neuromolecular medicine. 2006; 8(3):319-28. doi: 10.1385/nmm:8:3:319. [PMID: 16775383]
  • D Wüstner. Improved visualization and quantitative analysis of fluorescent membrane sterol in polarized hepatic cells. Journal of microscopy. 2005 Oct; 220(Pt 1):47-64. doi: 10.1111/j.1365-2818.2005.01516.x. [PMID: 16269063]
  • Manasa V Gudheti, Sum P Lee, Dganit Danino, Steven P Wrenn. Combined interaction of phospholipase C and apolipoprotein A-I with small unilamellar lecithin-cholesterol vesicles: influence of apolipoprotein A-I concentration and vesicle composition. Biochemistry. 2005 May; 44(19):7294-304. doi: 10.1021/bi047317m. [PMID: 15882068]
  • Jan Lochman, Tomas Kasparovsky, Jiri Damborsky, Hanan Osman, Antoine Marais, Radka Chaloupkova, Michel Ponchet, Jean-Pierre Blein, Vladimir Mikes. Construction of cryptogein mutants, a proteinaceous elicitor from Phytophthora, with altered abilities to induce a defense reaction in tobacco cells. Biochemistry. 2005 May; 44(17):6565-72. doi: 10.1021/bi0502285. [PMID: 15850390]
  • Daniel Wüstner, Mousumi Mondal, Ira Tabas, Frederick R Maxfield. Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic (Copenhagen, Denmark). 2005 May; 6(5):396-412. doi: 10.1111/j.1600-0854.2005.00285.x. [PMID: 15813750]
  • Weimin Zhang, Avery L McIntosh, Hai Xu, Di Wu, Todd Gruninger, Barbara Atshaves, J C Steve Liu, Friedhelm Schroeder. Structural analysis of sterol distributions in the plasma membrane of living cells. Biochemistry. 2005 Mar; 44(8):2864-84. doi: 10.1021/bi048172m. [PMID: 15723530]
  • Michelle Olsher, Su-In Yoon, Parkson Lee-Gau Chong. Role of sterol superlattice in free radical-induced sterol oxidation in lipid membranes. Biochemistry. 2005 Feb; 44(6):2080-7. doi: 10.1021/bi047710s. [PMID: 15697233]
  • Chao-Sheng Cheng, Dharmaraj Samuel, Yaw-Jen Liu, Je-Chyi Shyu, Szu-Ming Lai, Ku-Feng Lin, Ping-Chiang Lyu. Binding mechanism of nonspecific lipid transfer proteins and their role in plant defense. Biochemistry. 2004 Nov; 43(43):13628-36. doi: 10.1021/bi048873j. [PMID: 15504025]
  • Adalberto M Gallegos, Avery L McIntosh, Barbara P Atshaves, Friedhelm Schroeder. Structure and cholesterol domain dynamics of an enriched caveolae/raft isolate. The Biochemical journal. 2004 Sep; 382(Pt 2):451-61. doi: 10.1042/bj20031562. [PMID: 15149285]
  • Mingming Hao, Sushmita Mukherjee, Yu Sun, Frederick R Maxfield. Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. The Journal of biological chemistry. 2004 Apr; 279(14):14171-8. doi: 10.1074/jbc.m309793200. [PMID: 14734557]
  • Mei Mei Wang, Michelle Olsher, István P Sugár, Parkson Lee-Gau Chong. Cholesterol superlattice modulates the activity of cholesterol oxidase in lipid membranes. Biochemistry. 2004 Mar; 43(8):2159-66. doi: 10.1021/bi035982+. [PMID: 14979712]
  • Daniel Wüstner, Mousumi Mondal, Amy Huang, Frederick R Maxfield. Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells. Journal of lipid research. 2004 Mar; 45(3):427-37. doi: 10.1194/jlr.m300440-jlr200. [PMID: 14679167]
  • Andrew J Guarino, Thomas N Tulenko, Steven P Wrenn. Cholesterol crystal nucleation from enzymatically modified low-density lipoproteins: combined effect of sphingomyelinase and cholesterol esterase. Biochemistry. 2004 Feb; 43(6):1685-93. doi: 10.1021/bi035747r. [PMID: 14769046]
  • Jiwei Wang, Megha, Erwin London. Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): implications for lipid raft structure and function. Biochemistry. 2004 Feb; 43(4):1010-8. doi: 10.1021/bi035696y. [PMID: 14744146]
  • Barbara P Atshaves, Adalberto M Gallegos, Avery L McIntosh, Ann B Kier, Friedhelm Schroeder. Sterol carrier protein-2 selectively alters lipid composition and cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell fibroblast plasma membranes. Biochemistry. 2003 Dec; 42(49):14583-98. doi: 10.1021/bi034966+. [PMID: 14661971]
  • Avery L McIntosh, Adalberto M Gallegos, Barbara P Atshaves, Stephen M Storey, Deepak Kannoju, Friedhelm Schroeder. Fluorescence and multiphoton imaging resolve unique structural forms of sterol in membranes of living cells. The Journal of biological chemistry. 2003 Feb; 278(8):6384-403. doi: 10.1074/jbc.m205472200. [PMID: 12456684]
  • Karin John, Janek Kubelt, Peter Müller, Daniel Wüstner, Andreas Herrmann. Rapid transbilayer movement of the fluorescent sterol dehydroergosterol in lipid membranes. Biophysical journal. 2002 Sep; 83(3):1525-34. doi: 10.1016/s0006-3495(02)73922-2. [PMID: 12202377]
  • Jesper E Mogensen, Reinhard Wimmer, Jørgen N Larsen, Michael D Spangfort, Daniel E Otzen. The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. The Journal of biological chemistry. 2002 Jun; 277(26):23684-92. doi: 10.1074/jbc.m202065200. [PMID: 11953433]
  • Mingming Hao, Sharron X Lin, Ola J Karylowski, Daniel Wüstner, Timothy E McGraw, Frederick R Maxfield. Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. The Journal of biological chemistry. 2002 Jan; 277(1):609-17. doi: 10.1074/jbc.m108861200. [PMID: 11682487]
  • R Rukmini, S S Rawat, S C Biswas, A Chattopadhyay. Cholesterol organization in membranes at low concentrations: effects of curvature stress and membrane thickness. Biophysical journal. 2001 Oct; 81(4):2122-34. doi: 10.1016/s0006-3495(01)75860-2. [PMID: 11566783]
  • S P Wrenn, M Gudheti, A N Veleva, E W Kaler, S P Lee. Characterization of model bile using fluorescence energy transfer from dehydroergosterol to dansylated lecithin. Journal of lipid research. 2001 Jun; 42(6):923-34. doi: 10.1016/s0022-2275(20)31616-3. [PMID: 11369800]
  • L M Loura, M A Castanho, A Fedorov, M Prieto. A photophysical study of the polyene antibiotic filipin. Self-aggregation and filipin--ergosterol interaction. Biochimica et biophysica acta. 2001 Feb; 1510(1-2):125-35. doi: 10.1016/s0005-2736(00)00341-2. [PMID: 11342153]
  • H Osman, V Mikes, M L Milat, M Ponchet, D Marion, T Prangé, B F Maume, S Vauthrin, J P Blein. Fatty acids bind to the fungal elicitor cryptogein and compete with sterols. FEBS letters. 2001 Jan; 489(1):55-8. doi: 10.1016/s0014-5793(01)02078-6. [PMID: 11231013]
  • N A Avdulov, S V Chochina, U Igbavboa, W G Wood. Cholesterol efflux to high-density lipoproteins and apolipoprotein A-I phosphatidylcholine complexes is inhibited by ethanol: role of apolipoprotein structure and cooperative interaction of phosphatidylcholine and cholesterol. Biochemistry. 2000 Aug; 39(34):10599-606. doi: 10.1021/bi0008534. [PMID: 10956052]
  • J K Schoer, A M Gallegos, A L McIntosh, O Starodub, A B Kier, J T Billheimer, F Schroeder. Lysosomal membrane cholesterol dynamics. Biochemistry. 2000 Jul; 39(26):7662-77. doi: 10.1021/bi992686h. [PMID: 10869172]
  • A Frolov, A Petrescu, B P Atshaves, P T So, E Gratton, G Serrero, F Schroeder. High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach. The Journal of biological chemistry. 2000 Apr; 275(17):12769-80. doi: 10.1074/jbc.275.17.12769. [PMID: 10777574]
  • A M Gallegos, J K Schoer, O Starodub, A B Kier, J T Billheimer, F Schroeder. A potential role for sterol carrier protein-2 in cholesterol transfer to mitochondria. Chemistry and physics of lipids. 2000 Mar; 105(1):9-29. doi: 10.1016/s0009-3084(99)00128-0. [PMID: 10727111]
  • K H Cheng, J Virtanen, P Somerharju. Fluorescence studies of dehydroergosterol in phosphatidylethanolamine/phosphatidylcholine bilayers. Biophysical journal. 1999 Dec; 77(6):3108-19. doi: 10.1016/s0006-3495(99)77141-9. [PMID: 10585932]
  • S P Wrenn, E W Kaler, S P Lee. A fluorescence energy transfer study of lecithin-cholesterol vesicles in the presence of phospholipase C. Journal of lipid research. 1999 Aug; 40(8):1483-94. doi: 10.1016/s0022-2275(20)33391-5. [PMID: 10428985]
  • S Vauthrin, V Mikes, M L Milat, M Ponchet, B Maume, H Osman, J P Blein. Elicitins trap and transfer sterols from micelles, liposomes and plant plasma membranes. Biochimica et biophysica acta. 1999 Jul; 1419(2):335-42. doi: 10.1016/s0005-2736(99)00083-8. [PMID: 10407084]
  • S Mukherjee, X Zha, I Tabas, F R Maxfield. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophysical journal. 1998 Oct; 75(4):1915-25. doi: 10.1016/s0006-3495(98)77632-5. [PMID: 9746532]
  • V Mikes, M L Milat, M Ponchet, F Panabières, P Ricci, J P Blein. Elicitins, proteinaceous elicitors of plant defense, are a new class of sterol carrier proteins. Biochemical and biophysical research communications. 1998 Apr; 245(1):133-9. doi: 10.1006/bbrc.1998.8341. [PMID: 9535796]
  • V Mikes, M L Milat, M Ponchet, P Ricci, J P Blein. The fungal elicitor cryptogein is a sterol carrier protein. FEBS letters. 1997 Oct; 416(2):190-2. doi: 10.1016/s0014-5793(97)01193-9. [PMID: 9369212]
  • U Igbavboa, N A Avdulov, S V Chochina, W G Wood. Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E, or both proteins. Journal of neurochemistry. 1997 Oct; 69(4):1661-7. doi: 10.1046/j.1471-4159.1997.69041661.x. [PMID: 9326295]
  • P W Albro, P Bilski, J T Corbett, J L Schroeder, C F Chignell. Photochemical reactions and phototoxicity of sterols: novel self-perpetuating mechanisms for lipid photooxidation. Photochemistry and photobiology. 1997 Sep; 66(3):316-25. doi: 10.1111/j.1751-1097.1997.tb03154.x. [PMID: 9297976]
  • F Liu, I P Sugar, P L Chong. Cholesterol and ergosterol superlattices in three-component liquid crystalline lipid bilayers as revealed by dehydroergosterol fluorescence. Biophysical journal. 1997 May; 72(5):2243-54. doi: 10.1016/s0006-3495(97)78868-4. [PMID: 9129827]
  • K J van Erpecum, M C Carey. Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability. Biochimica et biophysica acta. 1997 Apr; 1345(3):269-82. doi: 10.1016/s0005-2760(97)00002-7. [PMID: 9150247]
  • A Frolov, J K Woodford, E J Murphy, J T Billheimer, F Schroeder. Fibroblast membrane sterol kinetic domains: modulation by sterol carrier protein-2 and liver fatty acid binding protein. Journal of lipid research. 1996 Sep; 37(9):1862-74. doi: 10.1016/s0022-2275(20)37551-9. [PMID: 8895052]
  • A Frolov, J K Woodford, E J Murphy, J T Billheimer, F Schroeder. Spontaneous and protein-mediated sterol transfer between intracellular membranes. The Journal of biological chemistry. 1996 Jul; 271(27):16075-83. doi: 10.1074/jbc.271.27.16075. [PMID: 8663152]
  • H Saito, T Minamida, I Arimoto, T Handa, K Miyajima. Physical states of surface and core lipids in lipid emulsions and apolipoprotein binding to the emulsion surface. The Journal of biological chemistry. 1996 Jun; 271(26):15515-20. doi: 10.1074/jbc.271.26.15515. [PMID: 8663047]
  • U Igbavboa, N A Avdulov, F Schroeder, W G Wood. Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice. Journal of neurochemistry. 1996 Apr; 66(4):1717-25. doi: 10.1046/j.1471-4159.1996.66041717.x. [PMID: 8627330]
  • J Kavecansky, F Schroeder, C H Joiner. Deoxygenation-induced alterations in sickle cell membrane cholesterol exchange. The American journal of physiology. 1995 Nov; 269(5 Pt 1):C1105-11. doi: 10.1152/ajpcell.1995.269.5.c1105. [PMID: 7491897]
  • S M Colles, J K Woodford, D Moncecchi, S C Myers-Payne, L R McLean, J T Billheimer, F Schroeder. Cholesterol interaction with recombinant human sterol carrier protein-2. Lipids. 1995 Sep; 30(9):795-803. doi: 10.1007/bf02533954. [PMID: 8577222]
  • J K Woodford, S M Colles, S Myers-Payne, J T Billheimer, F Schroeder. Sterol carrier protein-2 stimulates intermembrane sterol transfer by direct membrane interaction. Chemistry and physics of lipids. 1995 May; 76(1):73-84. doi: 10.1016/0009-3084(95)02436-m. [PMID: 7788802]
  • F Schroeder, J K Woodford, J Kavecansky, W G Wood, C Joiner. Cholesterol domains in biological membranes. Molecular membrane biology. 1995 Jan; 12(1):113-9. doi: 10.3109/09687689509038505. [PMID: 7767369]
  • P L Chong. Evidence for regular distribution of sterols in liquid crystalline phosphatidylcholine bilayers. Proceedings of the National Academy of Sciences of the United States of America. 1994 Oct; 91(21):10069-73. doi: 10.1073/pnas.91.21.10069. [PMID: 7937839]
  • Q T Li, W H Sawyer. Effect of cholesteryl ester on the distribution of fluorescent cholesterol analogues in triacylglycerol-rich emulsions. Biochimica et biophysica acta. 1993 Feb; 1166(2-3):145-53. doi: 10.1016/0005-2760(93)90090-v. [PMID: 8443230]
  • P Butko, I Hapala, G Nemecz, F Schroeder. Sterol domains in phospholipid membranes: dehydroergosterol polarization measures molecular sterol transfer. Journal of biochemical and biophysical methods. 1992 Mar; 24(1-2):15-37. doi: 10.1016/0165-022x(92)90043-a. [PMID: 1560178]
  • T W Gadella, K W Wirtz. The low-affinity lipid binding site of the non-specific lipid transfer protein. Implications for its mode of action. Biochimica et biophysica acta. 1991 Nov; 1070(1):237-45. doi: 10.1016/0005-2736(91)90170-d. [PMID: 1661153]
  • F Schroeder, G Nemecz, W G Wood, C Joiner, G Morrot, M Ayraut-Jarrier, P F Devaux. Transmembrane distribution of sterol in the human erythrocyte. Biochimica et biophysica acta. 1991 Jul; 1066(2):183-92. doi: 10.1016/0005-2736(91)90185-b. [PMID: 1854783]
  • J R Jefferson, J P Slotte, G Nemecz, A Pastuszyn, T J Scallen, F Schroeder. Intracellular sterol distribution in transfected mouse L-cell fibroblasts expressing rat liver fatty acid-binding protein. The Journal of biological chemistry. 1991 Mar; 266(9):5486-96. doi: NULL. [PMID: 2005092]
  • F Schroeder, P Butko, I Hapala, T J Scallen. Intermembrane cholesterol transfer: role of sterol carrier proteins and phosphatidylserine. Lipids. 1990 Nov; 25(11):669-74. doi: 10.1007/bf02544032. [PMID: 2280670]
  • W G Wood, F Schroeder, L Hogy, A M Rao, G Nemecz. Asymmetric distribution of a fluorescent sterol in synaptic plasma membranes: effects of chronic ethanol consumption. Biochimica et biophysica acta. 1990 Jun; 1025(2):243-6. doi: 10.1016/0005-2736(90)90103-u. [PMID: 2364080]
  • P Butko, I Hapala, T J Scallen, F Schroeder. Acidic phospholipids strikingly potentiate sterol carrier protein 2 mediated intermembrane sterol transfer. Biochemistry. 1990 May; 29(17):4070-7. doi: 10.1021/bi00469a007. [PMID: 2361131]
  • Y L Kao, P L Chong, C H Huang. Time-resolved fluorometric and differential scanning calorimetric investigation of dehydroergosterol in 1-stearoyl-2-caprylphosphatidylcholine bilayers. Biochemistry. 1990 Feb; 29(5):1315-22. doi: 10.1021/bi00457a030. [PMID: 2322566]
  • F Schroeder, P Butko, G Nemecz, T J Scallen. Interaction of fluorescent delta 5,7,9(11),22-ergostatetraen-3 beta-ol with sterol carrier protein-2. The Journal of biological chemistry. 1990 Jan; 265(1):151-7. doi: 10.1016/s0021-9258(19)40208-1. [PMID: 2294101]
  • L K Bar, P L Chong, Y Barenholz, T E Thompson. Spontaneous transfer between phospholipid bilayers of dehydroergosterol, a fluorescent cholesterol analog. Biochimica et biophysica acta. 1989 Jul; 983(1):109-12. doi: 10.1016/0005-2736(89)90386-6. [PMID: 2758045]
  • F Schroeder, G Nemecz. Interaction of sphingomyelins and phosphatidylcholines with fluorescent dehydroergosterol. Biochemistry. 1989 Jul; 28(14):5992-6000. doi: 10.1021/bi00440a041. [PMID: 2775747]
  • W D Sweet, F Schroeder. Polyunsaturated fatty acids alter sterol transbilayer domains in LM fibroblast plasma membrane. FEBS letters. 1988 Feb; 229(1):188-92. doi: 10.1016/0014-5793(88)80824-x. [PMID: 2831087]
  • G Smutzer. A fluorescent sterol probe study of human serum low-density lipoproteins. Biochimica et biophysica acta. 1988 Feb; 958(3):323-33. doi: 10.1016/0005-2760(88)90217-2. [PMID: 3342245]
  • F Schroeder, Y Barenholz, E Gratton, T E Thompson. A fluorescence study of dehydroergosterol in phosphatidylcholine bilayer vesicles. Biochemistry. 1987 May; 26(9):2441-8. doi: 10.1021/bi00383a007. [PMID: 3607026]
  • P L Chong, T E Thompson. Depolarization of dehydroergosterol in phospholipid bilayers. Biochimica et biophysica acta. 1986 Dec; 863(1):53-62. doi: 10.1016/0005-2736(86)90386-x. [PMID: 3778912]
  • A B Kier, W D Sweet, M S Cowlen, F Schroeder. Regulation of transbilayer distribution of a fluorescent sterol in tumor cell plasma membranes. Biochimica et biophysica acta. 1986 Oct; 861(2):287-301. doi: NULL. [PMID: 3756161]
  • R T Fischer, M S Cowlen, M E Dempsey, F Schroeder. Fluorescence of delta 5,7,9(11),22-ergostatetraen-3 beta-ol in micelles, sterol carrier protein complexes, and plasma membranes. Biochemistry. 1985 Jun; 24(13):3322-31. doi: 10.1021/bi00334a037. [PMID: 4027244]