Pitavastatin (BioDeep_00001883183)
Main id: BioDeep_00000018477
代谢物信息卡片
(3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
化学式: C25H23FNO4- (420.161103)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F
InChI: InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/p-1/b12-11+/t18-,19-/m1/s1
描述信息
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents
D004791 - Enzyme Inhibitors > D019161 - Hydroxymethylglutaryl-CoA Reductase Inhibitors
D009676 - Noxae > D000963 - Antimetabolites
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:71260
- ChEBI: CHEBI:32020
- KEGG: C13334
- PubChem: 24848419
- CAS: 147511-69-1
- PubChem: 586078
- PDB-CCD: PV9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Michael T Lu, Heather Ribaudo, Borek Foldyna, Markella V Zanni, Thomas Mayrhofer, Julia Karady, Jana Taron, Kathleen V Fitch, Sara McCallum, Tricia H Burdo, Kayla Paradis, Sandeep S Hedgire, Nandini M Meyersohn, Christopher DeFilippi, Carlos D Malvestutto, Audra Sturniolo, Marissa Diggs, Sue Siminski, Gerald S Bloomfield, Beverly Alston-Smith, Patrice Desvigne-Nickens, Edgar T Overton, Judith S Currier, Judith A Aberg, Carl J Fichtenbaum, Udo Hoffmann, Pamela S Douglas, Steven K Grinspoon. Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial.
JAMA cardiology.
2024 Apr; 9(4):323-334. doi:
10.1001/jamacardio.2023.5661. [PMID: 38381407] - M John Chapman, Alexina Orsoni, Natalie A Mellett, Anh Nguyen, Paul Robillard, Jonathan E Shaw, Philippe Giral, Patrice Thérond, Debi Swertfeger, W Sean Davidson, Peter J Meikle. Pitavastatin treatment remodels the HDL subclass lipidome and proteome in hypertriglyceridemia.
Journal of lipid research.
2024 02; 65(2):100494. doi:
10.1016/j.jlr.2023.100494. [PMID: 38160756] - Kiwamu Kamiya, Makoto Takei, Toshiyuki Nagai, Toru Miyoshi, Hiroshi Ito, Yoshihiro Fukumoto, Hitoshi Obara, Tatsuyuki Kakuma, Ichiro Sakuma, Hiroyuki Daida, Satoshi Iimuro, Hiroaki Shimokawa, Takeshi Kimura, Ryozo Nagai, Toshihisa Anzai. Association between Non-Lipid Residual Risk Factors and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Pitavastatin: An Observation from the REAL-CAD Study.
Journal of atherosclerosis and thrombosis.
2024 Jan; 31(1):61-80. doi:
10.5551/jat.64304. [PMID: 37574272] - Hina Arsh, Asif Ali, Raja Ram Khenhrani, Fnu Simran, Umbish Dino, Sweta Tamang, Fnu Manoj, Shuaita Bai, Monika Bai, Gianeshwareealias Rachna Panjwani, Deepak Kumar, Deepa Rani, Fnu Partab, Jahanzeb Malik. Efficacy and Safety of Pitavastatin in Patients with Impaired Glucose Tolerance: An Updated Review.
Current problems in cardiology.
2023 Jul; 48(11):101981. doi:
10.1016/j.cpcardiol.2023.101981. [PMID: 37473935] - Jiaying Wang, Jinliang Chen, Lu Wang, Dandan Yang, Rong Shao, Honggang Lou, Zourong Ruan, Bo Jiang. Evaluating the bioequivalence of two pitavastatin calcium formulations based on IVIVC modeling and clinical study.
Clinical and translational science.
2023 01; 16(1):85-91. doi:
10.1111/cts.13426. [PMID: 36178248] - Ming-Ting Chou, Anthony McGirr, Gwo-Ping Jong, Ting-Hsing Chao, I-Te Lee, Chun-Yao Huang, Ching-Pei Chen, Chang-Hsun Hsieh, Chieh-Hsiang Lu, Wayne Huey-Herng Sheu. Effect of 1PC111, a Fixed-dose Combination of Pitavastatin and Ezetimibe, Versus Pitavastatin or Ezetimibe Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia or Mixed Dyslipidemia: A Randomized, Double-blind, Multicenter, Phase III Study.
Clinical therapeutics.
2022 10; 44(10):1272-1281. doi:
10.1016/j.clinthera.2022.08.006. [PMID: 36030106] - Paul Grocki, Mark Woollam, Luqi Wang, Shengzhi Liu, Maitri Kalra, Amanda P Siegel, Bai-Yan Li, Hiroki Yokota, Mangilal Agarwal. Chemometric Analysis of Urinary Volatile Organic Compounds to Monitor the Efficacy of Pitavastatin Treatments on Mammary Tumor Progression over Time.
Molecules (Basel, Switzerland).
2022 Jul; 27(13):. doi:
10.3390/molecules27134277. [PMID: 35807522] - Joo Young Na, Eunsol Yang, Jae-Hoon Kim, In Sun Kwon, Eun-Heui Jin, Kyung-Sang Yu, Jinsook Kim, SeungHwan Lee, Jang Hee Hong. Comparative Pharmacokinetics Between a Fixed-Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects.
Clinical pharmacology in drug development.
2022 05; 11(5):615-622. doi:
10.1002/cpdd.1054. [PMID: 34997835] - Takuya Matsumoto, Shinichiro Yoshino, Tadashi Furuyama, Koichi Morisaki, Kaku Nakano, Jun-Ichiro Koga, Yoshihiko Maehara, Kimihiro Komori, Masaki Mori, Kensuke Egashira. Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial.
Journal of atherosclerosis and thrombosis.
2022 May; 29(5):731-746. doi:
10.5551/jat.58941. [PMID: 33907060] - Daiji Nagayama, Atsuhito Saiki, Yasuhiro Watanabe, Takashi Yamaguchi, Masahiro Ohira, Naoko Sato, Mizuho Kanayama, Masao Moroi, Yoh Miyashita, Kohji Shirai, Ichiro Tatsuno. Prevention of Cardiovascular Events with Pitavastatin is Associated with Increased Serum Lipoprotein Lipase Mass Level: Subgroup Analysis of the TOHO-LIP.
Journal of atherosclerosis and thrombosis.
2022 Apr; 29(4):451-463. doi:
10.5551/jat.62141. [PMID: 33642441] - Atsushi Kimura, Kenya Kamimura, Marina Ohkoshi-Yamada, Yoko Shinagawa-Kobayashi, Ryo Goto, Takashi Owaki, Chiyumi Oda, Osamu Shibata, Shinichi Morita, Norihiro Sakai, Hiroyuki Abe, Takeshi Yokoo, Akira Sakamaki, Hiroteru Kamimura, Shuji Terai. Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model.
Biochemical and biophysical research communications.
2022 03; 596(?):76-82. doi:
10.1016/j.bbrc.2022.01.086. [PMID: 35121372] - Francesco Fici, Gokhan Faikoglu, Bahar Arican Tarim, Nicolas Roberto Robles, Kostas Tsioufis, Guido Grassi, Barış Gungor. Pitavastatin: Coronary Atherosclerotic Plaques Changes and Cardiovascular Prevention.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.
2022 Mar; 29(2):137-144. doi:
10.1007/s40292-021-00496-0. [PMID: 35064911] - Jacqueline B McCrea, Azher Hussain, Bennett Ma, Graigory C Garrett, Raymond Evers, John E Laabs, S Aubrey Stoch, Marian Iwamoto. Assessment of Pharmacokinetic Interaction Between Gefapixant (MK-7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin.
Clinical pharmacology in drug development.
2022 03; 11(3):406-412. doi:
10.1002/cpdd.1047. [PMID: 34821075] - Daisaku Masuda, Shizuya Yamashita. Serum HDL-Cholesterol Level Does Not Influence Cardiovascular Event Rate under Sufficient Lowering of LDL-Cholesterol by Pitavatatin in Patients with Stable Coronary Artery Disease.
Journal of atherosclerosis and thrombosis.
2022 Jan; 29(1):8-10. doi:
10.5551/jat.ed165. [PMID: 33762513] - Ziqiang Li, Shuang Tian, Zengguang Wu, Xueyan Xu, Lei Lei, Yanfen Li, Baohe Wang, Yuhong Huang. Pharmacokinetic herb-disease-drug interactions: Effect of ginkgo biloba extract on the pharmacokinetics of pitavastatin, a substrate of Oatp1b2, in rats with non-alcoholic fatty liver disease.
Journal of ethnopharmacology.
2021 Nov; 280(?):114469. doi:
10.1016/j.jep.2021.114469. [PMID: 34329714] - Amirhossein Sahebkar, Nasim Kiaie, Armita Mahdavi Gorabi, Massimo R Mannarino, Vanessa Bianconi, Tannaz Jamialahmadi, Matteo Pirro, Maciej Banach. A comprehensive review on the lipid and pleiotropic effects of pitavastatin.
Progress in lipid research.
2021 11; 84(?):101127. doi:
10.1016/j.plipres.2021.101127. [PMID: 34509516] - Atsuhito Saiki, Yasuhiro Watanabe, Takashi Yamaguchi, Masahiro Ohira, Daiji Nagayama, Naoko Sato, Mizuho Kanayama, Mao Takahashi, Kazuhiro Shimizu, Masao Moroi, Yoh Miyashita, Kohji Shirai, Ichiro Tatsuno. CAVI-Lowering Effect of Pitavastatin May Be Involved in the Prevention of Cardiovascular Disease: Subgroup Analysis of the TOHO-LIP.
Journal of atherosclerosis and thrombosis.
2021 Oct; 28(10):1083-1094. doi:
10.5551/jat.60343. [PMID: 33342941] - Shinya Takahashi, Shu Kasama, Takuji Toyama, Shota Suzuki, Yukie Ito, Tomoaki Nakata, Masato Kasahara, Masahiko Kurabayashi. Assessment of therapeutic effects of statin on cardiac sympathetic nerve activity after reperfusion therapy in patients with first ST-segment elevation myocardial infarction and normal low-density lipoprotein cholesterol.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2021 Aug; 28(4):1449-1457. doi:
10.1007/s12350-019-01857-y. [PMID: 31440976] - Sheng Feng, Qingyan Bo, Hugh A Coleman, Jean Eric Charoin, Mingfen Zhu, Jim Xiao, Yuyan Jin. Further Evaluation of Coproporphyrins as Clinical Endogenous Markers for OATP1B.
Journal of clinical pharmacology.
2021 08; 61(8):1027-1034. doi:
10.1002/jcph.1817. [PMID: 33460165] - Christine M Bowman, Buyun Chen, Jonathan Cheong, Liling Liu, Yuan Chen, Jialin Mao. Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via Physiologically Based Pharmacokinetic Modeling.
Drug metabolism and disposition: the biological fate of chemicals.
2021 07; 49(7):530-539. doi:
10.1124/dmd.120.000315. [PMID: 33958385] - Katherine D Lynch, Michelle L Montonye, Dan-Dan Tian, Tarana Arman, Victoria O Oyanna, Baron J Bechtold, Tyler N Graf, Nicholas H Oberlies, Mary F Paine, John D Clarke. Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Phytotherapy research : PTR.
2021 Jun; 35(6):3286-3297. doi:
10.1002/ptr.7049. [PMID: 33587330] - Mahmoud H Teaima, Khaled M Abdel-Haleem, Rewan Osama, Mohamed A El-Nabarawi, Osama S Elnahas. A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study.
Drug design, development and therapy.
2021; 15(?):4229-4242. doi:
10.2147/dddt.s332729. [PMID: 34675486] - Daiji Nagayama, Atsuhito Saiki, Kohji Shirai. The Anti-Cancer Effect of Pitavastatin May Be a Drug-Specific Effect: Subgroup Analysis of the TOHO-LIP Study.
Vascular health and risk management.
2021; 17(?):169-173. doi:
10.2147/vhrm.s306540. [PMID: 33953560] - Yasufumi Katanasaka, Sae Hirano, Yoichi Sunagawa, Yusuke Miyazaki, Hikaru Sato, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Koji Hasegawa, Tatsuya Morimoto. Clinically Administered Doses of Pitavastatin and Rosuvastatin.
International heart journal.
2021; 62(6):1379-1386. doi:
10.1536/ihj.21-231. [PMID: 34853228] - Xiaomin Liang, Yeojin Park, Natalie DeForest, Jia Hao, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill Smith, Yurong Lai. In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation.
Drug metabolism and disposition: the biological fate of chemicals.
2020 12; 48(12):1283-1292. doi:
10.1124/dmd.120.000163. [PMID: 33037043] - In-Kyung Jeong, Sung-Rae Kim. Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study).
Endocrinology and metabolism (Seoul, Korea).
2020 12; 35(4):882-891. doi:
10.3803/enm.2020.723. [PMID: 33261312] - Hiroyuki Arashi, Junichi Yamaguchi, Erisa Kawada-Watanabe, Hisao Otsuki, Haruki Sekiguchi, Hiroshi Ogawa, Nobuhisa Hagiwara. The Effects of Lipid-Lowering Therapy on Serum Eicosapentaenoic Acid to Arachidonic Acid Ratio: An HIJ-PROPER Sub-Analysis.
Journal of cardiovascular pharmacology and therapeutics.
2020 11; 25(6):548-555. doi:
10.1177/1074248420931621. [PMID: 32567339] - Yan Xu, Yanqing Wu. Atorvastatin associated with gamma glutamyl transpeptidase elevation in a hyperlipidemia patient: A case report and literature review.
Medicine.
2020 Oct; 99(40):e22572. doi:
10.1097/md.0000000000022572. [PMID: 33019469] - Hisao Otsuki, Hiroyuki Arashi, Junichi Yamaguchi, Erisa Kawada-Watanabe, Hiroshi Ogawa, Nobuhisa Hagiwara. Effect of Ezetimibe + Pitavastatin on Cardiovascular Outcomes in Patients with ST-Segment Elevation Myocardial Infarction (from the HIJ-PROPER Study).
The American journal of cardiology.
2020 10; 132(?):15-21. doi:
10.1016/j.amjcard.2020.06.069. [PMID: 32773226] - Sang-Hyun Ihm, Woo-Baek Chung, Jong-Min Lee, Byung-Hee Hwang, Ki-Dong Yoo, Sung-Ho Her, Woo-Hyuk Song, In-Ho Chae, Tae-Ho Park, Ju-Han Kim, Dong Woon Jeon, Byung-Ryul Cho, Seung-Ho Kang, Sang-Don Park, Jin-Bae Lee, Jeong-Taek Woo, Byung-Wan Lee, Kyung-Ah Han, Kyung-Heon Won, Hyo-Soo Kim, Jae-Myung Yu, Choon Hee Chung, Hae-Jin Kim, Ho-Chan Cho, Ki-Bae Seung. Efficacy and Tolerability of Pitavastatin Versus Pitavastatin/Fenofibrate in High-risk Korean Patients with Mixed Dyslipidemia: A Multicenter, Randomized, Double-blinded, Parallel, Therapeutic Confirmatory Clinical Trial.
Clinical therapeutics.
2020 10; 42(10):2021-2035.e3. doi:
10.1016/j.clinthera.2020.08.002. [PMID: 32891418] - Rui-Xia Xu, Yan Zhang, Yue Zhang, Ya-Ru Wu, Xiao-Lin Li, Yuan-Lin Guo, Geng Liu, Qian Dong, Jian-Jun Li. Effects of Pitavastatin on Lipoprotein Subfractions and Oxidized Low-density Lipoprotein in Patients with Atherosclerosis.
Current medical science.
2020 Oct; 40(5):879-884. doi:
10.1007/s11596-020-2263-4. [PMID: 33123903] - Hae-Young Lee, Ki-Hoon Han, Woo-Baek Chung, Sung-Ho Her, Tae-Ho Park, Seung-Woon Rha, So-Yeon Choi, Kyung-Tae Jung, Jong-Seon Park, Pum-Joon Kim, Jong-Min Lee, Myung-Ho Jeong, Eun-Seok Shin, Hyeon-Cheol Gwon, Kyoo-Rok Han, Jei-Keon Chae, Woo-Shik Kim, Dong-Ju Choi, Bum-Kee Hong, Si-Wan Choi, Namsik Chung. Safety and Efficacy of Pitavastatin in Patients With Impaired Fasting Glucose and Hyperlipidemia: A Randomized, Open-labeled, Multicentered, Phase IV Study.
Clinical therapeutics.
2020 10; 42(10):2036-2048. doi:
10.1016/j.clinthera.2020.07.013. [PMID: 32921501] - Masatoki Yoshida, Kazufumi Nakamura, Toru Miyoshi, Masashi Yoshida, Megumi Kondo, Kaoru Akazawa, Tomonari Kimura, Hiroaki Ohtsuka, Yuko Ohno, Daiji Miura, Hiroshi Ito. Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet.
Cardiovascular diabetology.
2020 09; 19(1):149. doi:
10.1186/s12933-020-01132-2. [PMID: 32979918] - Edgar T Overton, Amy Kantor, Kathleen V Fitch, Paul Muntner, Khuanchai Supparatpinyo, Mosepele Mosepele, Lerato Mohapi, Sandra Wagner Cardoso, Sandesh Patil, Marcus V G de Lacerda, Grace McComsey, Judith A Aberg, Pamela S Douglas, Steven K Grinspoon, Heather Ribaudo, Christina M Wyatt. An Evaluation of Baseline Kidney Function in the REPRIEVE Trial of Pitavastatin in Human Immunodeficiency Virus.
The Journal of infectious diseases.
2020 07; 222(Suppl 1):S41-S51. doi:
10.1093/infdis/jiaa222. [PMID: 32645164] - David C Boettiger, Anthony T Newall, Pairoj Chattranukulchai, Romanee Chaiwarith, Suwimon Khusuwan, Anchalee Avihingsanon, Andrew Phillips, Eran Bendavid, Matthew G Law, James G Kahn, Jeremy Ross, Sergio Bautista-Arredondo, Sasisopin Kiertiburanakul. Statins for atherosclerotic cardiovascular disease prevention in people living with HIV in Thailand: a cost-effectiveness analysis.
Journal of the International AIDS Society.
2020 06; 23 Suppl 1(?):e25494. doi:
10.1002/jia2.25494. [PMID: 32562359] - Naeun Lee, Nirmala Tilija Pun, Won-Jun Jang, Jung Woo Bae, Chul-Ho Jeong. Pitavastatin induces apoptosis in oral squamous cell carcinoma through activation of FOXO3a.
Journal of cellular and molecular medicine.
2020 06; 24(12):7055-7066. doi:
10.1111/jcmm.15389. [PMID: 32406610] - Takayoshi Nakaoka, Yuta Uetake, Ken-Ichi Kaneko, Takashi Niwa, Hidenori Ochiai, Satsuki Irie, Yoshie Suezaki, Natsumi Otsuka, Emi Hayashinaka, Yasuhiro Wada, Yilong Cui, Kazuya Maeda, Hiroyuki Kusuhara, Yuichi Sugiyama, Takamitsu Hosoya, Yasuyoshi Watanabe. Practical Synthesis of [18F]Pitavastatin and Evaluation of Hepatobiliary Transport Activity in Rats by Positron Emission Tomography.
Molecular pharmaceutics.
2020 06; 17(6):1884-1898. doi:
10.1021/acs.molpharmaceut.9b01284. [PMID: 32271581] - Mayui Nakazawa, Hiroyuki Arashi, Junichi Yamaguchi, Hiroshi Ogawa, Nobuhisa Hagiwara. Lower levels of high-density lipoprotein cholesterol are associated with increased cardiovascular events in patients with acute coronary syndrome.
Atherosclerosis.
2020 06; 303(?):21-28. doi:
10.1016/j.atherosclerosis.2020.05.005. [PMID: 32474302] - Yongin Cho, Hyangkyu Lee, Hyun Ki Park, Eun Yeong Choe, Hye Jin Wang, Ryeong-Hyeon Kim, Youjin Kim, Eun Seok Kang. Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo.
Journal of atherosclerosis and thrombosis.
2020 May; 27(5):429-440. doi:
10.5551/jat.50039. [PMID: 31527323] - Erisa Kawada-Watanabe, Junichi Yamaguchi, Haruki Sekiguchi, Hiroyuki Arashi, Hiroshi Ogawa, Nobuhisa Hagiwara. Targeting high-sensitivity C-reactive protein levels in acute coronary syndrome patients undergoing contemporary lipid-lowering therapy: a sub-analysis of the HIJ-PROPER trial.
Journal of cardiology.
2020 05; 75(5):500-506. doi:
10.1016/j.jjcc.2019.09.015. [PMID: 31699568] - Hiroaki Takeda, Yoshihiro Izumi, Shohei Tamura, Tomonari Koike, Yui Koike, Masashi Shiomi, Takeshi Bamba. Lipid Profiling of Serum and Lipoprotein Fractions in Response to Pitavastatin Using an Animal Model of Familial Hypercholesterolemia.
Journal of proteome research.
2020 03; 19(3):1100-1108. doi:
10.1021/acs.jproteome.9b00602. [PMID: 31965805] - Misari Patel, Charmy Kothari. Quantitative bio-analysis of pitavastatin and candesartan in rat plasma by HPLC-UV: Assessment of pharmacokinetic drug-drug interaction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Feb; 1138(?):121962. doi:
10.1016/j.jchromb.2019.121962. [PMID: 31915110] - Junying Wang, Juan Liu, Xiangrong Song, Chunmei Fu. Simultaneous Determination of Telmisartan and Pitavastatin Calcium in Intestinal Perfusate by HPLC: Application to Intestinal Absorption Interaction Study.
Pharmaceutical nanotechnology.
2020; 8(4):313-322. doi:
10.2174/2211738508666200607181727. [PMID: 32515316] - Krishnaprasad Baby, Swastika Maity, Chetan H Mehta, Akhil Suresh, Usha Y Nayak, Yogendra Nayak. Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19.
F1000Research.
2020; 9(?):1166. doi:
10.12688/f1000research.26359.1. [PMID: 33204411] - Christine M Bowman, Eugene Chen, Liuxi Chen, Yi-Chen Chen, Xiaorong Liang, Matthew Wright, Yuan Chen, Jialin Mao. Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma.
Drug metabolism and disposition: the biological fate of chemicals.
2020 01; 48(1):18-24. doi:
10.1124/dmd.119.088948. [PMID: 31699807] - Luqi Wang, Yue Wang, Andy Chen, Meghana Teli, Rika Kondo, Aydin Jalali, Yao Fan, Shengzhi Liu, Xinyu Zhao, Amanda Siegel, Kazumasa Minami, Mangilal Agarwal, Bai-Yan Li, Hiroki Yokota. Pitavastatin slows tumor progression and alters urine-derived volatile organic compounds through the mevalonate pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 12; 33(12):13710-13721. doi:
10.1096/fj.201901388r. [PMID: 31585508] - Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith, Yurong Lai. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
Drug metabolism and disposition: the biological fate of chemicals.
2019 12; 47(12):1433-1442. doi:
10.1124/dmd.119.088922. [PMID: 31582395] - Christina Trueck, Chih-Hsuan Hsin, Oliver Scherf-Clavel, Elke Schaeffeler, Rebekka Lenssen, Malaz Gazzaz, Marleen Gersie, Max Taubert, Maria Quasdorff, Matthias Schwab, Martina Kinzig, Fritz Sörgel, Marc S Stoffel, Uwe Fuhr. A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.
Clinical pharmacology and therapeutics.
2019 12; 106(6):1398-1407. doi:
10.1002/cpt.1564. [PMID: 31247117] - Jae H Chang, Yi-Chen Chen, Jonathan Cheong, Robert S Jones, Jodie Pang. Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats.
Drug metabolism and disposition: the biological fate of chemicals.
2019 11; 47(11):1307-1313. doi:
10.1124/dmd.119.088278. [PMID: 31492695] - Hiroyuki Kimura, Yusuke Yagi, Mutsumi Mikamo, Kazuya Maeda, Shinya Kagawa, Kenji Arimitsu, Tatsuya Higashi, Ryuichi Nishii, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hiroyuki Kusuhara, Hideo Saji. Evaluation of transporter-mediated hepatobiliary transport of newly developed 18F-labeled pitavastatin derivative, PTV-F1, in rats by PET imaging.
Drug metabolism and pharmacokinetics.
2019 Oct; 34(5):317-324. doi:
10.1016/j.dmpk.2019.05.006. [PMID: 31331824] - Oliver Scherf-Clavel, Martina Kinzig, Marc S Stoffel, Uwe Fuhr, Fritz Sörgel. Quantification of adefovir and pitavastatin in human plasma and urine by LC-MS/MS: A useful tool for drug-drug interaction studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Sep; 1125(?):121718. doi:
10.1016/j.jchromb.2019.121718. [PMID: 31330406] - Hiroyuki Arashi, Junichi Yamaguchi, Erisa Kawada-Watanabe, Ryo Koyanagi, Haruki Sekiguchi, Fumiaki Mori, Shoji Haruta, Yasuhiro Ishii, Satoshi Murasaki, Kazuhito Suzuki, Takao Yamauchi, Hiroshi Ogawa, Nobuhisa Hagiwara. Polyunsaturated Fatty Acid Impact on Clinical Outcomes in Acute Coronary Syndrome Patients With Dyslipidemia: Subanalysis of HIJ-PROPER.
Journal of the American Heart Association.
2019 08; 8(16):e012953. doi:
10.1161/jaha.119.012953. [PMID: 31390907] - Liv Weichien Chen, Chin-Sheng Lin, Min-Chien Tsai, Shao-Fu Shih, Zhu Wei Lim, Sy-Jou Chen, Pi-Fen Tsui, Ling-Jun Ho, Jenn-Haung Lai, Jun-Ting Liou. Pitavastatin Exerts Potent Anti-Inflammatory and Immunomodulatory Effects via the Suppression of AP-1 Signal Transduction in Human T Cells.
International journal of molecular sciences.
2019 Jul; 20(14):. doi:
10.3390/ijms20143534. [PMID: 31330988] - Yusuke Yagi, Hiroyuki Kimura, Haruka Okuda, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hideo Saji. Evaluation of [18F]pitavastatin as a positron emission tomography tracer for in vivo organic transporter polypeptide function.
Nuclear medicine and biology.
2019 Jul; 74-75(?):25-31. doi:
10.1016/j.nucmedbio.2019.08.001. [PMID: 31450072] - Swati Kaushik, Ameesha Tomar, Susrutha Puthanmadhom Narayanan, Tapas Chandra Nag, Dharamvir Singh Arya, Jagriti Bhatia. Pitavastatin attenuates cisplatin-induced renal injury by targeting MAPK and apoptotic pathways.
The Journal of pharmacy and pharmacology.
2019 Jul; 71(7):1072-1081. doi:
10.1111/jphp.13090. [PMID: 30957246] - Jae H Chang, Xiaolin Zhang, Kirsten Messick, Yi-Chen Chen, Eugene Chen, Jonathan Cheong, Justin Ly. Unremarkable impact of Oatp inhibition on the liver concentration of fluvastatin, lovastatin and pitavastatin in wild-type and Oatp1a/1b knockout mouse.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 May; 49(5):602-610. doi:
10.1080/00498254.2018.1478167. [PMID: 29768081] - Rafael Carmena, D John Betteridge. Diabetogenic Action of Statins: Mechanisms.
Current atherosclerosis reports.
2019 04; 21(6):23. doi:
10.1007/s11883-019-0780-z. [PMID: 31037345] - Christine M Bowman, Hideaki Okochi, Leslie Z Benet. The Presence of a Transporter-Induced Protein Binding Shift: A New Explanation for Protein-Facilitated Uptake and Improvement for In Vitro-In Vivo Extrapolation.
Drug metabolism and disposition: the biological fate of chemicals.
2019 04; 47(4):358-363. doi:
10.1124/dmd.118.085779. [PMID: 30674616] - James C Y Chan, Shawn P F Tan, Zee Upton, Eric C Y Chan. Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing.
ALTEX.
2019; 36(4):597-612. doi:
10.14573/altex.1812051. [PMID: 31079160] - Jung Wook Lim, Han Saem Jeong, Soon Jun Hong, Hyo Jeong Kim, Young Chan Kim, Bong Gyun Kang, Su Min Jeon, Jae Young Cho, Seung Hoon Lee, Hyung Joon Joo, Jae Hyoung Park, Cheol Woong Yu. Effects of lowest-dose vs. highest-dose pitavastatin on coronary neointimal hyperplasia at 12-month follow-up in type 2 diabetic patients with non-ST elevation acute coronary syndrome: an optical coherence tomography analysis.
Heart and vessels.
2019 Jan; 34(1):62-73. doi:
10.1007/s00380-018-1227-0. [PMID: 30047013] - Ramsha Iqbal, Md Sayeed Akhtar, Md Quamrul Hassan, Zeeba Jairajpuri, Mohd Akhtar, Abul Kalam Najmi. Pitavastatin ameliorates myocardial damage by preventing inflammation and collagen deposition via reduced free radical generation in isoproterenol-induced cardiomyopathy.
Clinical and experimental hypertension (New York, N.Y. : 1993).
2019; 41(5):434-443. doi:
10.1080/10641963.2018.1501059. [PMID: 30192645] - Annett Kunze, Emmanuel Njumbe Ediage, Lieve Dillen, Mario Monshouwer, Jan Snoeys. Clinical Investigation of Coproporphyrins as Sensitive Biomarkers to Predict Mild to Strong OATP1B-Mediated Drug-Drug Interactions.
Clinical pharmacokinetics.
2018 12; 57(12):1559-1570. doi:
10.1007/s40262-018-0648-3. [PMID: 29663259] - Erisa Kawada-Watanabe, Junichi Yamaguchi, Keigo Kanbayashi, Haruki Sekiguchi, Hiroyuki Arashi, Hiroshi Ogawa, Nobuhisa Hagiwara. Predictive Value of Baseline High-Sensitivity C-Reactive Protein Level and Renal Function for Patients With Acute Coronary Syndrome Undergoing Aggressive Lipid-Lowering Therapy: A Subanalysis of HIJ-PROPER.
The American journal of cardiology.
2018 12; 122(11):1817-1823. doi:
10.1016/j.amjcard.2018.08.028. [PMID: 30270178] - Jianning Zhang, Yijia Shao, Yin Liu, Jun Tao. A Multi-Center, Open-Label, Two-Arm Parallel Group Non-inferiority Randomized Controlled Trial Evaluating the Effect of Pitavastatin, Compared to Atorvastatin, on Glucose Metabolism in Prediabetics with Hypertension and Dyslipidemia: Rationale and Design for the China Hemoglobin A1c Metabolism Protection Union Study (CAMPUS).
Cardiovascular drugs and therapy.
2018 12; 32(6):581-589. doi:
10.1007/s10557-018-6826-6. [PMID: 30187345] - Kaku Nakano, Tetsuya Matoba, Jun-Ichiro Koga, Yushi Kashihara, Masato Fukae, Ichiro Ieiri, Masanari Shiramoto, Shin Irie, Junji Kishimoto, Koji Todaka, Kensuke Egashira. Safety, Tolerability, and Pharmacokinetics of NK-104-NP.
International heart journal.
2018 Sep; 59(5):1015-1025. doi:
10.1536/ihj.17-555. [PMID: 30158384] - Gaizun Hu, Osamu Ito, Rong Rong, Akihiro Sakuyama, Takahiro Miura, Daisuke Ito, Yoshiko Ogawa, Masahiro Kohzuki. Pitavastatin Upregulates Nitric Oxide Synthases in the Kidney of Spontaneously Hypertensive Rats and Wistar-Kyoto Rats.
American journal of hypertension.
2018 09; 31(10):1139-1146. doi:
10.1093/ajh/hpy098. [PMID: 29955802] - Pallabi Mitra, Samantha Weinheimer, Meeghan Michalewicz, Mitchell E Taub. Prediction and Quantification of Hepatic Transporter-Mediated Uptake of Pitavastatin Utilizing a Combination of the Relative Activity Factor Approach and Mechanistic Modeling.
Drug metabolism and disposition: the biological fate of chemicals.
2018 07; 46(7):953-963. doi:
10.1124/dmd.118.080614. [PMID: 29666154] - Patrick Poulin, Sami Haddad. Extrapolation of the Hepatic Clearance of Drugs in the Absence of Albumin In Vitro to That in the Presence of Albumin In Vivo: Comparative Assessement of 2 Extrapolation Models Based on the Albumin-Mediated Hepatic Uptake Theory and Limitations and Mechanistic Insights.
Journal of pharmaceutical sciences.
2018 07; 107(7):1791-1797. doi:
10.1016/j.xphs.2018.03.012. [PMID: 29567347] - Junichi Yamaguchi, Erisa Kawada-Watanabe, Ryo Koyanagi, Hiroyuki Arashi, Haruki Sekiguchi, Koichi Nakao, Tetsuya Tobaru, Hiroyuki Tanaka, Toshiaki Oka, Yasuhiro Endo, Katsumi Saito, Tatsuro Uchida, Kunihiko Matsui, Hiroshi Ogawa, Nobuhisa Hagiwara. Baseline serum sitosterol level as predictor of adverse clinical events in acute coronary syndrome patients with dyslipidaemia: A sub-analysis of HIJ-PROPER.
Atherosclerosis.
2018 07; 274(?):139-145. doi:
10.1016/j.atherosclerosis.2018.04.036. [PMID: 29772482] - Ayşe Ufuk, Rachel E Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A David Rodrigues, Larry M Tremaine, Manthena V S Varma, J Brian Houston, Aleksandra Galetin. In Vitro-In Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey.
The Journal of pharmacology and experimental therapeutics.
2018 06; 365(3):688-699. doi:
10.1124/jpet.118.247767. [PMID: 29643253] - Xiaoyan Cui, Zhenqiang Fu, Menghan Wang, Xiaofei Nan, Boai Zhang. Pitavastatin treatment induces neuroprotection through the BDNF-TrkB signalling pathway in cultured cerebral neurons after oxygen-glucose deprivation.
Neurological research.
2018 May; 40(5):391-397. doi:
10.1080/01616412.2018.1447318. [PMID: 29544396] - Katsumi Miyauchi, Takeshi Kimura, Hiroaki Shimokawa, Hiroyuki Daida, Satoshi Iimuro, Hiroshi Iwata, Yukio Ozaki, Ichiro Sakuma, Yoshihisa Nakagawa, Kiyoshi Hibi, Takafumi Hiro, Yoshihiro Fukumoto, Seiji Hokimoto, Yasuo Ohashi, Hiroshi Ohtsu, Yasushi Saito, Masunori Matsuzaki, Ryozo Nagai. Rationale and Design of Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) Trial.
International heart journal.
2018 Mar; 59(2):315-320. doi:
10.1536/ihj.17-557. [PMID: 29503404] - Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka, Yuichi Sugiyama. The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model.
Drug metabolism and disposition: the biological fate of chemicals.
2018 03; 46(3):259-267. doi:
10.1124/dmd.117.077115. [PMID: 29298773] - Kiyoshi Hibi, Shinjo Sonoda, Masanori Kawasaki, Yutaka Otsuji, Toyoaki Murohara, Hideki Ishii, Katsuhiko Sato, Ryoji Koshida, Yukio Ozaki, Masataka Sata, Yoshihiro Morino, Tadashi Miyamoto, Tetsuya Amano, Satoshi Morita, Ken Kozuma, Kazuo Kimura, Hisayoshi Fujiwara. Effects of Ezetimibe-Statin Combination Therapy on Coronary Atherosclerosis in Acute Coronary Syndrome.
Circulation journal : official journal of the Japanese Circulation Society.
2018 02; 82(3):757-766. doi:
10.1253/circj.cj-17-0598. [PMID: 29212965] - Toru Miyoshi, Kunihisa Kohno, Hirohiko Asonuma, Satoru Sakuragi, Makoto Nakahama, Yusuke Kawai, Tadahisa Uesugi, Takefumi Oka, Mitsuru Munemasa, Natsuki Takahashi, Naoki Mukohara, Seiji Habara, Yasushi Koyama, Kazufumi Nakamura, Hiroshi Ito. Effect of Intensive and Standard Pitavastatin Treatment With or Without Eicosapentaenoic Acid on Progression of Coronary Artery Calcification Over 12 Months - Prospective Multicenter Study.
Circulation journal : official journal of the Japanese Circulation Society.
2018 01; 82(2):532-540. doi:
10.1253/circj.cj-17-0419. [PMID: 28867681] - Emma L Wilkinson, James E Sidaway, Michael J Cross. Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
Journal of cellular physiology.
2018 Jan; 233(1):186-200. doi:
10.1002/jcp.26064. [PMID: 28639275] - Takeshi Mitsuhashi, Ryoko Uemoto, Kazue Ishikawa, Sumiko Yoshida, Yasumasa Ikeda, Shusuke Yagi, Toshio Matsumoto, Masashi Akaike, Ken-Ichi Aihara. Endothelial Nitric Oxide Synthase-Independent Pleiotropic Effects of Pitavastatin Against Atherogenesis and Limb Ischemia in Mice.
Journal of atherosclerosis and thrombosis.
2018 Jan; 25(1):65-80. doi:
10.5551/jat.37747. [PMID: 28592707] - Tetsu Watanabe, Kaoru Ando, Hyuma Daidoji, Yoichiro Otaki, Shigeo Sugawara, Motoyuki Matsui, Eiichiro Ikeno, Osamu Hirono, Hiroshi Miyawaki, Yoshinori Yashiro, Satoshi Nishiyama, Takanori Arimoto, Hiroki Takahashi, Tetsuro Shishido, Takehiko Miyashita, Takuya Miyamoto, Isao Kubota. A randomized controlled trial of eicosapentaenoic acid in patients with coronary heart disease on statins.
Journal of cardiology.
2017 Dec; 70(6):537-544. doi:
10.1016/j.jjcc.2017.07.007. [PMID: 28863874] - Jiangrong Huang, Xiaoyu Yang, Xiaochun Peng, Wei Huang. Inhibiting prenylation augments chemotherapy efficacy in renal cell carcinoma through dual inhibition on mitochondrial respiration and glycolysis.
Biochemical and biophysical research communications.
2017 11; 493(2):921-927. doi:
10.1016/j.bbrc.2017.09.120. [PMID: 28943437] - Kayoko Kanamitsu, Hiroyuki Kusuhara, John D Schuetz, Kenji Takeuchi, Yuichi Sugiyama. Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.
Journal of pharmaceutical sciences.
2017 09; 106(9):2566-2575. doi:
10.1016/j.xphs.2017.04.040. [PMID: 28456721] - Nobuhisa Hagiwara, Erisa Kawada-Watanabe, Ryo Koyanagi, Hiroyuki Arashi, Junichi Yamaguchi, Koichi Nakao, Tetsuya Tobaru, Hiroyuki Tanaka, Toshiaki Oka, Yasuhiro Endoh, Katsumi Saito, Tatsuro Uchida, Kunihiko Matsui, Hiroshi Ogawa. Low-density lipoprotein cholesterol targeting with pitavastatin + ezetimibe for patients with acute coronary syndrome and dyslipidaemia: the HIJ-PROPER study, a prospective, open-label, randomized trial.
European heart journal.
2017 Aug; 38(29):2264-2276. doi:
10.1093/eurheartj/ehx162. [PMID: 28430910] - Elizabeth de Wolf, Marwan Ibrahim Abdullah, Stefanie M Jones, Karen Menezes, Darren M Moss, Falko P Drijfhout, Sarah R Hart, Clare Hoskins, Euan A Stronach, Alan Richardson. Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.
Scientific reports.
2017 07; 7(1):5410. doi:
10.1038/s41598-017-05595-4. [PMID: 28710496] - Young Joon Hong, Myung Ho Jeong, Jang Ho Bae, Seok Kyu Oh, Seung Woon Rha, Seung Ho Hur, Sung Yun Lee, Sang Wook Kim, Kwang Soo Cha, In Ho Chae, Tae Hoon Ahn, Kee Sik Kim. Efficacy and safety of pitavastatins in patients with acute myocardial infarction: Livalo in Acute Myocardial Infarction Study (LAMIS) II.
The Korean journal of internal medicine.
2017 Jul; 32(4):656-667. doi:
10.3904/kjim.2016.016. [PMID: 28618772] - Judith A Aberg, Craig A Sponseller, Douglas J Ward, Vladimir A Kryzhanovski, Stuart E Campbell, Melanie A Thompson. Pitavastatin versus pravastatin in adults with HIV-1 infection and dyslipidaemia (INTREPID): 12 week and 52 week results of a phase 4, multicentre, randomised, double-blind, superiority trial.
The lancet. HIV.
2017 07; 4(7):e284-e294. doi:
10.1016/s2352-3018(17)30075-9. [PMID: 28416195] - Rhishikesh Thakare, Hongying Gao, Rachel E Kosa, Yi-An Bi, Manthena V S Varma, Matthew A Cerny, Raman Sharma, Max Kuhn, Bingshou Huang, Yiping Liu, Aijia Yu, Gregory S Walker, Mark Niosi, Larry Tremaine, Yazen Alnouti, A David Rodrigues. Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
Drug metabolism and disposition: the biological fate of chemicals.
2017 07; 45(7):721-733. doi:
10.1124/dmd.117.075275. [PMID: 28396527] - Angela Pirillo, Alberico L Catapano. Pitavastatin and HDL: Effects on plasma levels and function(s).
Atherosclerosis. Supplements.
2017 Jul; 27(?):e1-e9. doi:
10.1016/j.atherosclerosissup.2017.05.001. [PMID: 28716185] - Jie-Hua Shi, Qi Wang, Dong-Qi Pan, Ting-Ting Liu, Min Jiang. Characterization of interactions of simvastatin, pravastatin, fluvastatin, and pitavastatin with bovine serum albumin: multiple spectroscopic and molecular docking.
Journal of biomolecular structure & dynamics.
2017 May; 35(7):1529-1546. doi:
10.1080/07391102.2016.1188416. [PMID: 27484332] - Parag H Joshi, P Elliott Miller, Seth S Martin, Steven R Jones, Joseph M Massaro, Ralph B D'Agostino, Krishnaji R Kulkarni, Craig Sponseller, Peter P Toth. Greater remnant lipoprotein cholesterol reduction with pitavastatin compared with pravastatin in HIV-infected patients.
AIDS (London, England).
2017 04; 31(7):965-971. doi:
10.1097/qad.0000000000001423. [PMID: 28121706] - Sheridan M Hoy. Pitavastatin: A Review in Hypercholesterolemia.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2017 Apr; 17(2):157-168. doi:
10.1007/s40256-017-0213-8. [PMID: 28130659] - Şengül Beyaz, Kubilay Ükinç. [Pitavastatin and new diabetes development].
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2017 Apr; 45(Suppl 3):13-15. doi:
10.5543/tkda.2017.51635. [PMID: 28952473] - Nevrez Koylan. [Pitavastatin - tolerability and advers effect profile].
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2017 Apr; 45(Suppl 3):16-23. doi:
10.5543/tkda.2017.60246. [PMID: 28952474] - Vedat Sansoy. [The efficacy and safety of pitavastatin].
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2017 Apr; 45(Suppl 3):1-4. doi:
10.5543/tkda.2017.88459. [PMID: 28952470] - Tao Feng, Xiaoxing Huang, Qundi Liang, Yun Liang, Yong Yuan, Li Feng, Wenjun Wu, Xuehong Xiao, Ying Han. Effects of Pitavastatin on Lipid-rich Carotid Plaques Studied Using High-resolution Magnetic Resonance Imaging.
Clinical therapeutics.
2017 Mar; 39(3):620-629. doi:
10.1016/j.clinthera.2017.01.013. [PMID: 28185713] - Erisa Kawada-Watanabe, Hiroshi Ogawa, Ryo Koyanagi, Hiroyuki Arashi, Junichi Yamaguchi, Kunihiko Matsui, Nobuhisa Hagiwara. Rationale, design features, and baseline characteristics: The Heart Institute of Japan-PRoper level of lipid lOwering with Pitavastatin and Ezetimibe in acute coRonary syndrome (HIJ-PROPER).
Journal of cardiology.
2017 03; 69(3):536-541. doi:
10.1016/j.jjcc.2016.05.002. [PMID: 27349705] - Shruti Surendran, David Paul, Ratna Sushmita, Lavanya Krishna, Nirbhay Kumar Tiwari, Sanjeev Giri, Nanjappan Satheeshkumar. A validated LC-MS/MS method for the estimation of glimepiride and pitavastatin in rat plasma: Application to drug interaction studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Mar; 1046(?):218-225. doi:
10.1016/j.jchromb.2017.01.009. [PMID: 28159531] - Khondoker Alam, Taleah Farasyn, Alexandra Crowe, Kai Ding, Wei Yue. Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner.
PloS one.
2017; 12(11):e0186924. doi:
10.1371/journal.pone.0186924. [PMID: 29107984] - A J McFarland, A K Davey, S Anoopkumar-Dukie. Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells.
Mediators of inflammation.
2017; 2017(?):2582745. doi:
10.1155/2017/2582745. [PMID: 28546657] - Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Sae Hirano-Sunagawa, Masafumi Funamoto, Eriko Morimoto, Maki Komiyama, Akira Shimatsu, Noriko Satoh-Asahara, Hajime Yamakage, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto. Effect of statins on atherogenic serum amyloid A and α1-antitrypsin low-density lipoprotein complexes.
International journal of cardiology.
2016 Dec; 225(?):332-336. doi:
10.1016/j.ijcard.2016.09.116. [PMID: 27756037] - Xi Chen, Bei Xu, Jian Yang, Juan Liu, Dailong Fang, Yongjun Gu, Zhifei Jian, Minghai Tang, Chunmei Fu, Zhi Zhang, Chunling Jiang, Xiangrong Song. Simultaneous determination of telmisartan and pitavastatin in rat plasma by UPLC-MS/MS: Application to pharmacokinetic interaction study.
Journal of pharmaceutical and biomedical analysis.
2016 Nov; 131(?):373-379. doi:
10.1016/j.jpba.2016.09.006. [PMID: 27643859]