N-(N-(3-Amino-3-carboxypropyl)-3-amino-3-carboxypropyl)azetidine-2-carboxylic acid (BioDeep_00001880693)

   


代谢物信息卡片


N-(N-(3-Amino-3-carboxypropyl)-3-amino-3-carboxypropyl)azetidine-2-carboxylic acid

化学式: C12H21N3O6 (303.1430286)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN(C1C(=O)O)CCC(C(=O)O)NCCC(C(=O)O)N
InChI: InChI=1S/C12H21N3O6/c13-7(10(16)17)1-4-14-8(11(18)19)2-5-15-6-3-9(15)12(20)21/h7-9,14H,1-6,13H2,(H,16,17)(H,18,19)(H,20,21)

描述信息

同义名列表

1 个代谢物同义名

N-(N-(3-Amino-3-carboxypropyl)-3-amino-3-carboxypropyl)azetidine-2-carboxylic acid



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xi Wu, Yafeng Jia, Qian Ma, Tingting Wang, Jiena Xu, Hongli Chen, Mingxia Wang, Hui Song, Shuqing Cao. The transcription factor bZIP44 cooperates with MYB10 and MYB72 to regulate the response of Arabidopsis thaliana to iron deficiency stress. The New phytologist. 2024 Jun; 242(6):2586-2603. doi: 10.1111/nph.19706. [PMID: 38523234]
  • Ilya V Seregin, Anna D Kozhevnikova. Nicotianamine: A Key Player in Metal Homeostasis and Hyperaccumulation in Plants. International journal of molecular sciences. 2023 Jun; 24(13):. doi: 10.3390/ijms241310822. [PMID: 37446000]
  • Hiroyuki Seebach, Gabriel Radow, Michael Brunek, Frank Schulz, Markus Piotrowski, Ute Krämer. Arabidopsis Nicotianamine Synthases (NAS) comprise a common core-NAS domain fused to a variable auto-inhibitory C-terminus. The Journal of biological chemistry. 2023 Apr; ?(?):104732. doi: 10.1016/j.jbc.2023.104732. [PMID: 37086785]
  • Wentao Sun, Xiaojin J Zhou, Chen Chen, Xin Zhang, Xiaolong Tian, Ke Xiao, Chenxu Liu, Rumei Chen, Shaojiang Chen. Maize Interveinal Chlorosis 1 links the Yang Cycle and Fe homeostasis through Nicotianamine biosynthesis. Plant physiology. 2022 03; 188(4):2131-2145. doi: 10.1093/plphys/kiac009. [PMID: 35099564]
  • Jesse T Beasley, Julien P Bonneau, Laura T Moreno-Moyano, Damien L Callahan, Kate S Howell, Elad Tako, Julian Taylor, Raymond P Glahn, Rudi Appels, Alexander A T Johnson. Multi-year field evaluation of nicotianamine biofortified bread wheat. The Plant journal : for cell and molecular biology. 2022 03; 109(5):1168-1182. doi: 10.1111/tpj.15623. [PMID: 34902177]
  • S Gopika, Cyril Augustine. Theoretical studies on the coordination chemistry of phytosiderophores with special reference to Fe-nicotianamine complexes in graminaceous plants. Journal of molecular modeling. 2022 Feb; 28(3):71. doi: 10.1007/s00894-022-05065-3. [PMID: 35226207]
  • Xin Zhang, Ke Xiao, Suzhen Li, Jie Li, Jiaxing Huang, Rumei Chen, Sen Pang, Xiaojin Zhou. Genome-wide analysis of the NAAT, DMAS, TOM, and ENA gene families in maize suggests their roles in mediating iron homeostasis. BMC plant biology. 2022 Jan; 22(1):37. doi: 10.1186/s12870-021-03422-7. [PMID: 35039017]
  • Ghaya Alchoubassi, Katarzyna Kińska, Katarzyna Bierla, Ryszard Lobinski, Joanna Szpunar. Speciation of essential nutrient trace elements in coconut water. Food chemistry. 2021 Mar; 339(?):127680. doi: 10.1016/j.foodchem.2020.127680. [PMID: 32860999]
  • Yoshiko Murata, Masami Yoshida, Naho Sakamoto, Shiho Morimoto, Takehiro Watanabe, Kosuke Namba. Iron uptake mediated by the plant-derived chelator nicotianamine in the small intestine. The Journal of biological chemistry. 2021 Jan; 296(?):100195. doi: 10.1074/jbc.ra120.015861. [PMID: 33334885]
  • James F Collins. Iron chelates hitch a ride on PAT1. The Journal of biological chemistry. 2021 Jan; 296(?):100418. doi: 10.1016/j.jbc.2021.100418. [PMID: 33837730]
  • Clémentine Laffont, Pascal Arnoux. The ancient roots of nicotianamine: diversity, role, regulation and evolution of nicotianamine-like metallophores. Metallomics : integrated biometal science. 2020 10; 12(10):1480-1493. doi: 10.1039/d0mt00150c. [PMID: 33084706]
  • Yuta Kawakami, Navreet K Bhullar. Potential Implications of Interactions between Fe and S on Cereal Fe Biofortification. International journal of molecular sciences. 2020 Apr; 21(8):. doi: 10.3390/ijms21082827. [PMID: 32325653]
  • Huimin Zhang, Yang Li, Mengna Pu, Peng Xu, Gang Liang, Diqiu Yu. Oryza sativa POSITIVE REGULATOR OF IRON DEFICIENCY RESPONSE 2 (OsPRI2) and OsPRI3 are involved in the maintenance of Fe homeostasis. Plant, cell & environment. 2020 01; 43(1):261-274. doi: 10.1111/pce.13655. [PMID: 31674679]
  • Ruohan Xie, Jianqi Zhao, Lingli Lu, Jun Ge, Patrick H Brown, Shuai Wei, Runze Wang, Yabei Qiao, Samuel M Webb, Shengke Tian. Efficient phloem remobilization of Zn protects apple trees during the early stages of Zn deficiency. Plant, cell & environment. 2019 12; 42(12):3167-3181. doi: 10.1111/pce.13621. [PMID: 31325325]
  • Houqing Zeng, Xin Zhang, Ming Ding, Xiajun Zhang, Yiyong Zhu. Transcriptome profiles of soybean leaves and roots in response to zinc deficiency. Physiologia plantarum. 2019 Nov; 167(3):330-351. doi: 10.1111/ppl.12894. [PMID: 30536844]
  • Raviraj Banakar, Ana Alvarez Fernandez, Changfu Zhu, Javier Abadia, Teresa Capell, Paul Christou. The ratio of phytosiderophores nicotianamine to deoxymugenic acid controls metal homeostasis in rice. Planta. 2019 Oct; 250(4):1339-1354. doi: 10.1007/s00425-019-03230-2. [PMID: 31278466]
  • Shaopei Gao, Yunhua Xiao, Fan Xu, Xiaokai Gao, Shouyun Cao, Fengxia Zhang, Guodong Wang, Dale Sanders, Chengcai Chu. Cytokinin-dependent regulatory module underlies the maintenance of zinc nutrition in rice. The New phytologist. 2019 10; 224(1):202-215. doi: 10.1111/nph.15962. [PMID: 31131881]
  • Jesse T Beasley, Julien P Bonneau, Jose T Sánchez-Palacios, Laura T Moreno-Moyano, Damien L Callahan, Elad Tako, Raymond P Glahn, Enzo Lombi, Alexander A T Johnson. Metabolic engineering of bread wheat improves grain iron concentration and bioavailability. Plant biotechnology journal. 2019 08; 17(8):1514-1526. doi: 10.1111/pbi.13074. [PMID: 30623558]
  • Jesse T Beasley, Jonathan J Hart, Elad Tako, Raymond P Glahn, Alexander A T Johnson. Investigation of Nicotianamine and 2' Deoxymugineic Acid as Enhancers of Iron Bioavailability in Caco-2 Cells. Nutrients. 2019 Jun; 11(7):. doi: 10.3390/nu11071502. [PMID: 31262064]
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  • Xinxin Zhang, Di Zhang, Wei Sun, Tianzuo Wang. The Adaptive Mechanism of Plants to Iron Deficiency via Iron Uptake, Transport, and Homeostasis. International journal of molecular sciences. 2019 May; 20(10):. doi: 10.3390/ijms20102424. [PMID: 31100819]
  • Brigitta Müller, Krisztina Kovács, Hong-Diep Pham, Yusuf Kavak, Jiři Pechoušek, Libor Machala, Radek Zbořil, Kálmán Szenthe, Javier Abadía, Ferenc Fodor, Zoltán Klencsár, Ádám Solti. Chloroplasts preferentially take up ferric-citrate over iron-nicotianamine complexes in Brassica napus. Planta. 2019 Mar; 249(3):751-763. doi: 10.1007/s00425-018-3037-0. [PMID: 30382344]
  • Alessio Aprile, Erika Sabella, Marzia Vergine, Alessandra Genga, Maria Siciliano, Eliana Nutricati, Patrizia Rampino, Mariarosaria De Pascali, Andrea Luvisi, Antonio Miceli, Carmine Negro, Luigi De Bellis. Activation of a gene network in durum wheat roots exposed to cadmium. BMC plant biology. 2018 Oct; 18(1):238. doi: 10.1186/s12870-018-1473-4. [PMID: 30326849]
  • Maria Garnica, Eva Bacaicoa, Veronica Mora, Sara San Francisco, Roberto Baigorri, Angel Mari Zamarreño, Jose Maria Garcia-Mina. Shoot iron status and auxin are involved in iron deficiency-induced phytosiderophores release in wheat. BMC plant biology. 2018 Jun; 18(1):105. doi: 10.1186/s12870-018-1324-3. [PMID: 29866051]
  • Rakesh K Kumar, Heng-Hsuan Chu, Celina Abundis, Kenneth Vasques, David Chan Rodriguez, Ju-Chen Chia, Rong Huang, Olena K Vatamaniuk, Elsbeth L Walker. Iron-Nicotianamine Transporters Are Required for Proper Long Distance Iron Signaling. Plant physiology. 2017 Nov; 175(3):1254-1268. doi: 10.1104/pp.17.00821. [PMID: 28894019]
  • Takeshi Senoura, Emi Sakashita, Takanori Kobayashi, Michiko Takahashi, May Sann Aung, Hiroshi Masuda, Hiromi Nakanishi, Naoko K Nishizawa. The iron-chelate transporter OsYSL9 plays a role in iron distribution in developing rice grains. Plant molecular biology. 2017 Nov; 95(4-5):375-387. doi: 10.1007/s11103-017-0656-y. [PMID: 28871478]
  • Raviraj Banakar, Ana Alvarez Fernandez, Pablo Díaz-Benito, Javier Abadia, Teresa Capell, Paul Christou. Phytosiderophores determine thresholds for iron and zinc accumulation in biofortified rice endosperm while inhibiting the accumulation of cadmium. Journal of experimental botany. 2017 10; 68(17):4983-4995. doi: 10.1093/jxb/erx304. [PMID: 29048564]
  • Dong-Keun Lee, Pil Joong Chung, Jin Seo Jeong, Geupil Jang, Seung Woon Bang, Harin Jung, Youn Shic Kim, Sun-Hwa Ha, Yang Do Choi, Ju-Kon Kim. The rice OsNAC6 transcription factor orchestrates multiple molecular mechanisms involving root structural adaptions and nicotianamine biosynthesis for drought tolerance. Plant biotechnology journal. 2017 Jun; 15(6):754-764. doi: 10.1111/pbi.12673. [PMID: 27892643]
  • Chandan Kumar Gupta, Bhupinder Singh. Uninhibited biosynthesis and release of phytosiderophores in the presence of heavy metal (HM) favors HM remediation. Environmental science and pollution research international. 2017 Apr; 24(10):9407-9416. doi: 10.1007/s11356-017-8636-y. [PMID: 28233213]
  • Weilin Zhang, Chengqi Yan, Mei Li, Ling Yang, Bojun Ma, Hongyu Meng, Li Xie, Jianping Chen. Transcriptome Analysis Reveals the Response of Iron Homeostasis to Early Feeding by Small Brown Planthopper in Rice. Journal of agricultural and food chemistry. 2017 Feb; 65(6):1093-1101. doi: 10.1021/acs.jafc.6b04674. [PMID: 28112511]
  • Jelena Pavlovic, Jelena Samardzic, Ljiljana Kostic, Kristian H Laursen, Maja Natic, Gordana Timotijevic, Jan K Schjoerring, Miroslav Nikolic. Silicon enhances leaf remobilization of iron in cucumber under limited iron conditions. Annals of botany. 2016 08; 118(2):271-80. doi: 10.1093/aob/mcw105. [PMID: 27371693]
  • Ghassan Ghssein, Catherine Brutesco, Laurent Ouerdane, Clémentine Fojcik, Amélie Izaute, Shuanglong Wang, Christine Hajjar, Ryszard Lobinski, David Lemaire, Pierre Richaud, Romé Voulhoux, Akbar Espaillat, Felipe Cava, David Pignol, Elise Borezée-Durant, Pascal Arnoux. Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus. Science (New York, N.Y.). 2016 May; 352(6289):1105-9. doi: 10.1126/science.aaf1018. [PMID: 27230378]
  • Tomoko Ariga, Yuki Imura, Michio Suzuki, Etsuro Yoshimura. Determination of ferric iron chelators by high-performance liquid chromatography using luminol chemiluminescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2016 Mar; 1014(?):75-82. doi: 10.1016/j.jchromb.2016.01.048. [PMID: 26874881]
  • Tadakatsu Yoneyama, Satoru Ishikawa, Shu Fujimaki. Route and Regulation of Zinc, Cadmium, and Iron Transport in Rice Plants (Oryza sativa L.) during Vegetative Growth and Grain Filling: Metal Transporters, Metal Speciation, Grain Cd Reduction and Zn and Fe Biofortification. International journal of molecular sciences. 2015 Aug; 16(8):19111-29. doi: 10.3390/ijms160819111. [PMID: 26287170]
  • Kenji Hazama, Shinji Nagata, Tamaki Fujimori, Shuichi Yanagisawa, Tadakatsu Yoneyama. Concentrations of metals and potential metal-binding compounds and speciation of Cd, Zn and Cu in phloem and xylem saps from castor bean plants (Ricinus communis) treated with four levels of cadmium. Physiologia plantarum. 2015 Jun; 154(2):243-55. doi: 10.1111/ppl.12309. [PMID: 25403762]
  • Jean-Yves Cornu, Ulrich Deinlein, Stephan Höreth, Manuel Braun, Holger Schmidt, Michael Weber, Daniel P Persson, Søren Husted, Jan K Schjoerring, Stephan Clemens. Contrasting effects of nicotianamine synthase knockdown on zinc and nickel tolerance and accumulation in the zinc/cadmium hyperaccumulator Arabidopsis halleri. The New phytologist. 2015 Apr; 206(2):738-50. doi: 10.1111/nph.13237. [PMID: 25545296]
  • Saori Takahashi, Taku Yoshiya, Kumiko Yoshizawa-Kumagaye, Toshihiro Sugiyama. Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean. Biomedical research (Tokyo, Japan). 2015; 36(3):219-24. doi: 10.2220/biomedres.36.219. [PMID: 26106051]
  • Munkhtsetseg Tsednee, Shun-Chung Yang, Der-Chuen Lee, Kuo-Chen Yeh. Root-secreted nicotianamine from Arabidopsis halleri facilitates zinc hypertolerance by regulating zinc bioavailability. Plant physiology. 2014 Oct; 166(2):839-52. doi: 10.1104/pp.114.241224. [PMID: 25118254]
  • Stephan Clemens. Zn and Fe biofortification: the right chemical environment for human bioavailability. Plant science : an international journal of experimental plant biology. 2014 Aug; 225(?):52-7. doi: 10.1016/j.plantsci.2014.05.014. [PMID: 25017159]
  • Emmanuel Koen, Angélique Besson-Bard, Céline Duc, Jérémy Astier, Antoine Gravot, Pierre Richaud, Olivier Lamotte, Jossia Boucherez, Frédéric Gaymard, David Wendehenne. Arabidopsis thaliana nicotianamine synthase 4 is required for proper response to iron deficiency and to cadmium exposure. Plant science : an international journal of experimental plant biology. 2013 Aug; 209(?):1-11. doi: 10.1016/j.plantsci.2013.04.006. [PMID: 23759098]
  • Stephan Clemens, Ulrich Deinlein, Hassan Ahmadi, Stephan Höreth, Shimpei Uraguchi. Nicotianamine is a major player in plant Zn homeostasis. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2013 Aug; 26(4):623-32. doi: 10.1007/s10534-013-9643-1. [PMID: 23775667]
  • Matsuda Sanae, Aoyagi Yasuo. Green asparagus (Asparagus officinalis) prevented hypertension by an inhibitory effect on angiotensin-converting enzyme activity in the kidney of spontaneously hypertensive rats. Journal of agricultural and food chemistry. 2013 Jun; 61(23):5520-5. doi: 10.1021/jf3041066. [PMID: 23647085]
  • Roberto Terzano, Tanja Mimmo, Bart Vekemans, Laszlo Vincze, Gerald Falkenberg, Nicola Tomasi, Magali Schnell Ramos, Roberto Pinton, Stefano Cesco. Iron (Fe) speciation in xylem sap by XANES at a high brilliant synchrotron X-ray source: opportunities and limitations. Analytical and bioanalytical chemistry. 2013 Jun; 405(16):5411-9. doi: 10.1007/s00216-013-6959-1. [PMID: 23609785]
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