5-Formylcytosine (BioDeep_00001878019)
代谢物信息卡片
5-Formylcytosine
化学式: C5H5N3O2 (139.03817500000002)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NC(=O)NC(=C1C=O)N
InChI: InChI=1S/C5H5N3O2/c6-4-3(2-9)1-7-5(10)8-4/h1-2H,(H3,6,7,8,10)
描述信息
A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a formyl group.
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yulin Zheng, Yunlei Zhou, Xiaoting Cui, Hengming Yan, Lulu Cao, Lanlan Gao, Huanshun Yin. Investigation of the effect of antibiotics on 5-formylcytosine content in mazie seedling tissues based on photoelectrochemical biosensor.
Journal of hazardous materials.
2022 08; 436(?):129146. doi:
10.1016/j.jhazmat.2022.129146. [PMID: 35594676] - Zhenning Yu, Si-Yang Liu, Yanfei Zhang, Yunda Li, Yuzhi Xu, Danping Chen, Zong Dai, Xiaoyong Zou. Pearl Necklacelike Strategy Enables Quantification of Global 5-Hydroxymethylcytosine and 5-Formylcytosine by Inductively Coupled Plasma-Atomic Emission Spectrometry.
Analytical chemistry.
2021 06; 93(22):7787-7791. doi:
10.1021/acs.analchem.1c01548. [PMID: 34037387] - Marcos Viejo, Igor Yakovlev, Carl Gunnar Fossdal. Immunochemical Detection of Modified Species of Cytosine in Plant Tissues.
Methods in molecular biology (Clifton, N.J.).
2021; 2198(?):209-216. doi:
10.1007/978-1-0716-0876-0_17. [PMID: 32822034] - Igor A Yakovlev, Daniel Gackowski, Abdulkadir Abakir, Marcos Viejo, Alexey Ruzov, Ryszard Olinski, Marta Starczak, Carl Gunnar Fossdal, Konstantin V Krutovsky. Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome.
Scientific reports.
2019 12; 9(1):19314. doi:
10.1038/s41598-019-55826-z. [PMID: 31848418] - Danping Chen, Yang Wang, Mingming Mo, Junjie Zhang, Yanfei Zhang, Yuzhi Xu, Si-Yang Liu, Jun Chen, Yingjun Ma, Li Zhang, Zong Dai, Chun Cai, Xiaoyong Zou. Polymerization retardation isothermal amplification (PRIA): a strategy enables sensitively quantify genome-wide 5-methylcytosine oxides rapidly on handy instruments with nanoscale sample input.
Nucleic acids research.
2019 11; 47(19):e119. doi:
10.1093/nar/gkz704. [PMID: 31418020] - Chenxu Zhu, Yun Gao, Jinying Peng, Fuchou Tang, Chengqi Yi. Single-Cell 5fC Sequencing.
Methods in molecular biology (Clifton, N.J.).
2019; 1979(?):251-267. doi:
10.1007/978-1-4939-9240-9_16. [PMID: 31028643] - Shaofei Ji, Iwen Fu, Spandana Naldiga, Hongzhao Shao, Ashis K Basu, Suse Broyde, Natalia Y Tretyakova. 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells.
Nucleic acids research.
2018 07; 46(13):6455-6469. doi:
10.1093/nar/gky444. [PMID: 29905846] - Chenxu Zhu, Yun Gao, Hongshan Guo, Bo Xia, Jinghui Song, Xinglong Wu, Hu Zeng, Kehkooi Kee, Fuchou Tang, Chengqi Yi. Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution.
Cell stem cell.
2017 05; 20(5):720-731.e5. doi:
10.1016/j.stem.2017.02.013. [PMID: 28343982] - Martyna Modrzejewska, Maciej Gawronski, Magdalena Skonieczna, Ewelina Zarakowska, Marta Starczak, Marek Foksinski, Joanna Rzeszowska-Wolny, Daniel Gackowski, Ryszard Olinski. Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA.
Free radical biology & medicine.
2016 12; 101(?):378-383. doi:
10.1016/j.freeradbiomed.2016.10.535. [PMID: 27833031] - Shangxian Ma, Huiping Sun, Yan Li, Honglan Qi, Jianbin Zheng. Discrimination between 5-Hydroxymethylcytosine and 5-Methylcytosine in DNA via Selective Electrogenerated Chemiluminescence (ECL) Labeling.
Analytical chemistry.
2016 10; 88(20):9934-9940. doi:
10.1021/acs.analchem.6b01265. [PMID: 27620533] - Bo Xia, Dali Han, Xingyu Lu, Zhaozhu Sun, Ankun Zhou, Qiangzong Yin, Hu Zeng, Menghao Liu, Xiang Jiang, Wei Xie, Chuan He, Chengqi Yi. Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
Nature methods.
2015 Nov; 12(11):1047-50. doi:
10.1038/nmeth.3569. [PMID: 26344045] - Ruichuan Yin, Jiezhen Mo, Meiling Lu, Hailin Wang. Detection of human urinary 5-hydroxymethylcytosine by stable isotope dilution HPLC-MS/MS analysis.
Analytical chemistry.
2015 Feb; 87(3):1846-52. doi:
10.1021/ac5038895. [PMID: 25551771] - Daniel Gackowski, Ewelina Zarakowska, Marta Starczak, Martyna Modrzejewska, Ryszard Olinski. Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships.
PloS one.
2015; 10(12):e0144859. doi:
10.1371/journal.pone.0144859. [PMID: 26660343] - Zhizhong Gong, Jian-Kang Zhu. Active DNA demethylation by oxidation and repair.
Cell research.
2011 Dec; 21(12):1649-51. doi:
10.1038/cr.2011.140. [PMID: 21862972]