Cefpimizole (BioDeep_00001877994)
代谢物信息卡片
化学式: C28H26N6O10S2 (670.1151776)
中文名称: 头孢咪唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)C4=C(NC=N4)C(=O)O)C(=O)O)C[N+]5=CC=C(C=C5)CCS(=O)(=O)[O-]
InChI: InChI=1S/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- T Toyoguchi, Y Nakagawa. [Nephrotoxicity and drug interaction of vancomycin (2)].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1996 May; 107(5):225-35. doi:
10.1254/fpj.107.225. [PMID: 8690304] - E Ueta, K Yoneda, T Yamamoto, T Osaki. Upregulatory effects of cefpimizole natrium on human leukocytes.
International journal of immunopharmacology.
1992 Jul; 14(5):877-85. doi:
10.1016/0192-0561(92)90087-2. [PMID: 1324894] - E Novak, D B Lakings, L M Paxton. Tolerance and disposition of cefpimizole in normal human volunteers after intramuscular administration.
Antimicrobial agents and chemotherapy.
1987 Nov; 31(11):1706-10. doi:
10.1128/aac.31.11.1706. [PMID: 3435119] - J M Friis, D B Lakings. High-performance liquid chromatographic method for the determination of cefpimizole in tissue.
Journal of chromatography.
1986 Oct; 382(?):399-404. doi:
10.1016/s0378-4347(00)83551-3. [PMID: 3782412] - D B Lakings, E Novak, J M Friis, C M Lunan, L M Paxton. Pharmacokinetics and dose proportionality of cefpimizole in normal humans after intramuscular administration.
Antimicrobial agents and chemotherapy.
1986 Feb; 29(2):271-7. doi:
10.1128/aac.29.2.271. [PMID: 3717932] - Y Obana, T Nishino, T Tanino. The therapeutic efficacy of AC-1370 against experimental infections in mice.
The Journal of antimicrobial chemotherapy.
1985 Dec; 16(6):727-34. doi:
10.1093/jac/16.6.727. [PMID: 4093344] - N Cho, K Fukunaga, K Kunii. [Pharmacokinetics and clinical studies on cefpimizole in the field of obstetrics and gynecology].
The Japanese journal of antibiotics.
1985 Apr; 38(4):926-39. doi:
NULL. [PMID: 4032730] - T Yamamoto, J Yasuda, M Tomioka, M Kanao, H Okada. [Fundamental and clinical studies on cefpimizole in the field of obstetrics and gynecology].
The Japanese journal of antibiotics.
1985 Apr; 38(4):987-94. doi:
NULL. [PMID: 4032735] - T Horii, K Kitamura, M Ikeda, M Shiota, K Teshima, K Noda. [Fundamental and clinical studies on cefpimizole in the field of obstetrics and gynecology].
The Japanese journal of antibiotics.
1985 Apr; 38(4):995-1000. doi:
NULL. [PMID: 4032736] - I Gorai, T Uemura, H Mizuguchi. [Fundamental and clinical studies of cefpimizole in the field of obstetric and gynecologic infections].
The Japanese journal of antibiotics.
1985 Apr; 38(4):954-65. doi:
NULL. [PMID: 4032732] - K Ito, K Matsunami, M Hayasaki, K Noda, Y Baba, H Kondo. [Fundamental and clinical studies of cefpimizole in obstetrics and gynecology].
The Japanese journal of antibiotics.
1985 Apr; 38(4):972-81. doi:
NULL. [PMID: 4032734] - D B Lakings, J M Friis, R J Brown, H R Allen. Pharmacokinetics of cefpimizole in normal humans after single- and multiple-dose intravenous infusions.
Antimicrobial agents and chemotherapy.
1984 Dec; 26(6):802-6. doi:
10.1128/aac.26.6.802. [PMID: 6524897] - M Takeuchi, M Iwata, M Kiguchi, M Kaga, K Shimpo, T Tanabe. [Chronic toxicity study of AC-1370 sodium, an antibiotics, intravenously administered in rats].
The Journal of toxicological sciences.
1984 Nov; 9(4):363-88. doi:
10.2131/jts.9.363. [PMID: 6527393] - S Hashimoto, H Ishii, T Fujimoto, S Tsubuku, Y Takasaki. Acute and subacute toxicity studies of AC-1370 sodium in mice and rats.
Toxicology letters.
1984 Nov; 23(2):135-40. doi:
10.1016/0378-4274(84)90117-6. [PMID: 6506087] - D B Lakings, J M Wozniak. High-performance liquid chromatographic methods for the determination of cefpimizole in plasma and urine.
Journal of chromatography.
1984 Jun; 308(?):261-71. doi:
10.1016/s0021-9673(01)87552-x. [PMID: 6430941]