amoscanate (BioDeep_00001877984)
代谢物信息卡片
化学式: C13H9N3O2S (271.0415454)
中文名称: 4-硝基-4-异硫氰基二苯胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1NC2=CC=C(C=C2)[N+](=O)[O-])N=C=S
InChI: InChI=1S/C13H9N3O2S/c17-16(18)13-7-5-12(6-8-13)15-11-3-1-10(2-4-11)14-9-19/h1-8,15H
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Conrad Johanson, Edward Stopa, Paul McMillan, Daniel Roth, Juergen Funk, Georg Krinke. The distributional nexus of choroid plexus to cerebrospinal fluid, ependyma and brain: toxicologic/pathologic phenomena, periventricular destabilization, and lesion spread.
Toxicologic pathology.
2011 Jan; 39(1):186-212. doi:
10.1177/0192623310394214. [PMID: 21189316] - T R Juneja, Arindam Talukdar, R L Gupta. Mutagenicity of sulfoscanate: a comparative study.
Mutation research.
2002 Jul; 518(2):155-61. doi:
10.1016/s1383-5718(02)00104-3. [PMID: 12113767] - A W Cheever, J G Macedonia, S Deb, E A Cheever, J E Mosimann. Persistence of eggs and hepatic fibrosis after treatment of Schistosoma mansoni-infected mice.
The American journal of tropical medicine and hygiene.
1992 Jun; 46(6):752-8. doi:
10.4269/ajtmh.1992.46.752. [PMID: 1320344] - A W Cheever, S Deb. Persistence of hepatic fibrosis and tissue eggs following treatment of Schistosoma japonicum infected mice.
The American journal of tropical medicine and hygiene.
1989 Jun; 40(6):620-8. doi:
10.4269/ajtmh.1989.40.620. [PMID: 2500856] - W M Kofi-Tsekpo, C W Karekezi. Detectability and measurability of amoscanate in plasma by TLC and HPLC.
Drugs under experimental and clinical research.
1988; 14(1):31-7. doi:
NULL. [PMID: 3391104] - J P Court, M Martin-Short, G M Lees. A comparison of the response of Dipetalonema viteae and Brugia pahangi adult worms to antifilarial agents in vitro.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ).
1986 Dec; 37(4):375-80. doi:
NULL. [PMID: 3563317] - T A Shapiro, J B Were, P Talalay, E Bueding, L Rocco, K Danso, R Massof, R Green, E D Mellits, P S Lietman. Clinical evaluation of amoscanate in healthy male volunteers.
The American journal of tropical medicine and hygiene.
1986 Sep; 35(5):945-53. doi:
10.4269/ajtmh.1986.35.945. [PMID: 3766854] - A A Sabah, C Fletcher, G Webbe, M J Doenhoff. Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
Experimental parasitology.
1985 Dec; 60(3):348-54. doi:
10.1016/0014-4894(85)90041-4. [PMID: 3935473] - B E Barton, D A Levy. The immune response to a schistosomacide, amoscanate. I. Serum antibody responses.
Journal of immunopharmacology.
1985; 7(3):343-71. doi:
10.3109/08923978509026481. [PMID: 2414366] - B E Barton, D A Levy. The immune response to a schistosomacide, amoscanate. II. Cell-mediated immune responses.
Journal of immunopharmacology.
1985; 7(3):373-83. doi:
10.3109/08923978509026482. [PMID: 4056413] - A Tawatsin, S Sirisinha, S Vajrasthira, D Bunnag, T Harinasuta. Evaluation of selected anthelmintic compounds for activity against Opisthorchis viverrini.
Tropenmedizin und Parasitologie.
1984 Jun; 35(2):85-90. doi:
NULL. [PMID: 6464190] - K A Crawford, H L Asch, J I Bruce, E Bueding, E R Smith. Efficacy of amoscanate against experimental schistosomal infections in monkeys.
The American journal of tropical medicine and hygiene.
1983 Sep; 32(5):1055-64. doi:
10.4269/ajtmh.1983.32.1055. [PMID: 6625061] - A B Vaidya, H G Sen, N A Mankodi, T Paul, U K Sheth. Phase 1 tolerability and searching dose studies with 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), a new anthelmintic.
British journal of clinical pharmacology.
1977 Aug; 4(4):463-7. doi:
10.1111/j.1365-2125.1977.tb00763.x. [PMID: 901739] - B J Vakil, N J Dalal, P N Shah. Clinical evaluation of a new anthelmintic - C. 9333 Go./CGP 4540 in human hookworm infection.
Transactions of the Royal Society of Tropical Medicine and Hygiene.
1977; 71(3):247-50. doi:
10.1016/0035-9203(77)90017-7. [PMID: 329490] - E Bueding, R Batzinger, G Petterson. Antischistosomal and some toxicological properties of a nitrodiphenylaminoisothiocyanate (C 9333-Go/CGP 4540).
Experientia.
1976 May; 32(5):604-6. doi:
10.1007/bf01990188. [PMID: 1278309]